关注
Sharrol Bachas
Sharrol Bachas
未知所在单位机构
在 evolutionaryscale.ai 的电子邮件经过验证
标题
引用次数
引用次数
年份
Unlocking de novo antibody design with generative artificial intelligence
A Shanehsazzadeh, S Bachas, M McPartlon, G Kasun, JM Sutton, ...
bioRxiv, 2023.01. 08.523187, 2023
462023
Antibody optimization enabled by artificial intelligence predictions of binding affinity and naturalness
S Bachas, G Rakocevic, D Spencer, AV Sastry, R Haile, JM Sutton, ...
BioRxiv, 2022.08. 16.504181, 2022
462022
Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR
S Bachas, C Eginton, D Gunio, H Wade
Proceedings of the National Academy of Sciences 108 (27), 11046-11051, 2011
452011
Allosteric coupling via distant disorder-to-order transitions
C Eginton, WJ Cressman, S Bachas, H Wade, D Beckett
Journal of molecular biology 427 (8), 1695-1704, 2015
352015
Convergent use of heptacoordination for cation selectivity by RNA and protein metalloregulators
ST Bachas, AR Ferré-D'Amaré
Cell chemical biology 25 (8), 962-973. e5, 2018
262018
Unlocking de novo antibody design with generative artificial intelligence. bioRxiv
A Shanehsazzadeh, S Bachas, M McPartlon, G Kasun, JM Sutton, ...
Posted online January, 2023
132023
Solution binding and structural analyses reveal potential multidrug resistance functions for SAV2435 and CTR107 and other GyrI-like proteins
A Moreno, JR Froehlig, S Bachas, D Gunio, T Alexander, A Vanya, ...
Biochemistry 55 (34), 4850-4863, 2016
112016
In vitro validated antibody design against multiple therapeutic antigens using generative inverse folding
A Shanehsazzadeh, J Alverio, G Kasun, S Levine, JA Khan, C Chung, ...
bioRxiv, 2023.12. 08.570889, 2023
62023
Unlocking de novo antibody design with generative artificial intelligence. bioRxiv (2023)
A Shanehsazzadeh, S Bachas, G Kasun, JM Sutton, AK Steiger, R Shuai, ...
URL https://www. biorxiv. org/content/early/2023/01/09/2023.01 8, 0
5
Charge is Major Determinant of Activation of the Ligand‐Responsive Multidrug Resistance Gene Regulator, BmrR
S Bachas, B Kohrs, H Wade
ChemMedChem 11 (10), 1038-1041, 2016
42016
Unconventional coupling between ligand recognition and allosteric control in the multidrug resistance gene regulator, BmrR
S Bachas, B Kohrs, H Wade
ChemMedChem 12 (6), 426-430, 2017
32017
AIntibody: an experimentally validated in silico antibody discovery design challenge
MF Erasmus, L Spector, F Ferrara, R DiNiro, TJ Pohl, K Perea-Schmittle, ...
Nature Biotechnology, 1-6, 2024
12024
ENGINEERED GYRI-LIKE MUTEIN APTAMERS, AND RELATED METHODS
H Cho, ST Bachas
US Patent App. 18/733,814, 2024
2024
Engineered gyri-like mutein aptamers, and related methods
HD Cho, ST Bachas
US Patent 12,104,201, 2024
2024
Back Cover: Unconventional Coupling between Ligand Recognition and Allosteric Control in the Multidrug Resistance Gene Regulator, BmrR (ChemMedChem 6/2017)
S Bachas, B Kohrs, H Wade
ChemMedChem 12 (6), 475-475, 2017
2017
Induced fit in the specific recognition of transition metal ions by a gene-regulatory RNA
ST Bachas, AR Ferre-D'Amare
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, A37-A37, 2017
2017
Cover Picture: Charge is Major Determinant of Activation of the Ligand‐Responsive Multidrug Resistance Gene Regulator, BmrR (ChemMedChem 10/2016)
S Bachas, B Kohrs, H Wade
ChemMedChem 11 (10), 1022-1022, 2016
2016
Multidrug recognition and Multidrug transcription activation by the gene regulator, BmrR
ST Bachas
Johns Hopkins University, 2014
2014
Allosteric Coupling via Communication of Distal Disorder-To-Order Transitions
D Beckett, C Eginton, S Bachas, H Wade
Biophysical Journal 106 (2), 438a, 2014
2014
系统目前无法执行此操作,请稍后再试。
文章 1–19