Chroman-4-one-and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells T Seifert, M Malo, T Kokkola, K Engen, M Friden-Saxin, EAA Wallen, ... Journal of Medicinal Chemistry 57 (23), 9870-9888, 2014 | 110 | 2014 |
Behavioral analysis of dopaminergic activation in zebrafish and rats reveals similar phenotypes F Ek, M Malo, M Åberg Andersson, C Wedding, J Kronborg, P Svensson, ... ACS chemical neuroscience 7 (5), 633-646, 2016 | 58 | 2016 |
Identification of the binding site of chroman-4-one-based sirtuin 2-selective inhibitors using photoaffinity labeling in combination with tandem mass spectrometry T Seifert, M Malo, J Lengqvist, C Sihlbom, EM Jarho, K Luthman Journal of Medicinal Chemistry 59 (23), 10794-10799, 2016 | 42 | 2016 |
Selective Pharmacophore Models of Dopamine D1 and D2 Full Agonists Based on Extended Pharmacophore Features M Malo, L Brive, K Luthman, P Svensson ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 232-246, 2010 | 31 | 2010 |
Investigation of D1 Receptor–Agonist Interactions and D1/D2 Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling M Malo, L Brive, K Luthman, P Svensson ChemMedChem 7 (3), 483-494, 2012 | 20 | 2012 |
Investigation of D2 Receptor–Agonist Interactions Using a Combination of Pharmacophore and Receptor Homology Modeling M Malo, L Brive, K Luthman, P Svensson ChemMedChem 7 (3), 471-482, 2012 | 17 | 2012 |
Chroman-4-one and chromone based somatostatin β-turn mimetics M Friden-Saxin, T Seifert, M Malo, K da Silva Andersson, N Pemberton, ... European Journal of Medicinal Chemistry 114, 59-64, 2016 | 16 | 2016 |
Chiral dihydrobenzofuran acids show potent retinoid X receptor–nuclear receptor related 1 protein dimer activation H Sundén, A Schäfer, M Scheepstra, S Leysen, M Malo, JN Ma, ... Journal of medicinal chemistry 59 (3), 1232-1238, 2016 | 16 | 2016 |
MeONH2· HCl-Mediated α-Methylenation/Conjugate Addition of α-Sulfonyl o-Hydroxyacetophenones with Methyl Sulfoxides: Route to 3-Sulfonylchroman-4-ones MY Chang, KT Chen Synthesis 53 (01), 135-145, 2021 | 9 | 2021 |
A scaffold replacement approach towards new sirtuin 2 inhibitors T Seifert, M Malo, T Kokkola, EJL Steen, K Meinander, EAA Wallen, ... Bioorganic & Medicinal Chemistry 28 (2), 115231, 2020 | 8 | 2020 |
Development of 7TM receptor-ligand complex models using ligand-biased, semi-empirical helix-bundle repacking in torsion space: application to the agonist interaction of the … M Malo, R Persson, P Svensson, K Luthman, L Brive Journal of Computer-Aided Molecular Design 27, 277-291, 2013 | 4 | 2013 |
Synthesis of cis-Oriented Vicinal Diphenylethylenes through a Lewis Acid-Promoted Annulation of Oxotriphenylhexanoates M Kamlar, E Henriksson, I Cisarova, M Malo, H Sundén The Journal of Organic Chemistry 86 (13), 8660-8671, 2021 | 3 | 2021 |
Discovery of Procognitive Antipsychotics by Combining Muscarinic M1 Receptor Structure–Activity Relationship with Systems Response Profiles in Zebrafish Larvae K Hellman, J Ohlsson, M Malo, R Olsson, F Ek ACS Chemical Neuroscience 11 (2), 173-183, 2019 | 3 | 2019 |
Inside Cover: Investigation of D2 Receptor–Agonist Interactions Using a Combination of Pharmacophore and Receptor Homology Modeling / Investigation of D1 Receptor–Agonist … M Malo, L Brive, K Luthman, P Svensson ChemMedChem 7 (3), 338-338, 2012 | 1 | 2012 |
Photoaffinity labeling approach towards binding site identification of chroman-4-one based sirtuin 2 inhibitors T Seifert, M Malo, J Lengqvist, C Sihlbom, E Jarho, K Luthman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
Selectivity of dopamine D1 and D2 receptor agonists–A combined computational approach M Malo | | 2012 |
Inside Cover: Selective Pharmacophore Models of Dopamine D1 and D2 Full Agonists Based on Extended Pharmacophore Features (ChemMedChem 2/2010) M Malo, L Brive, K Luthman, P Svensson ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 166-166, 2010 | | 2010 |
Selectivity of dopamine D1 and D2 receptor agonists M MALO | | |