| Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism KN Adams, K Takaki, LE Connolly, H Wiedenhoft, K Winglee, O Humbert, ... Cell 145 (1), 39-53, 2011 | 609 | 2011 |
| Mycobacterium marinum Infection of Adult Zebrafish Causes Caseating Granulomatous Tuberculosis and Is Moderated by Adaptive Immunity LE Swaim, LE Connolly, HE Volkman, O Humbert, DE Born, ... Infection and immunity 74 (11), 6108-6117, 2006 | 406 | 2006 |
| Superinfecting mycobacteria home to established tuberculous granulomas CL Cosma, O Humbert, L Ramakrishnan Nature immunology 5 (8), 828-835, 2004 | 220 | 2004 |
| In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production C Atkinson, O Humbert, JW Lampe, S Berman The Journal of nutrition 134 (3), 596-599, 2004 | 195 | 2004 |
| Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection K Chan, T Knaak, L Satkamp, O Humbert, S Falkow, L Ramakrishnan Proceedings of the National Academy of Sciences 99 (6), 3920-3925, 2002 | 157 | 2002 |
| Targeted homology-directed repair in blood stem and progenitor cells with CRISPR nanoformulations R Shahbazi, G Sghia-Hughes, JL Reid, S Kubek, KG Haworth, O Humbert, ... Nature materials 18 (10), 1124-1132, 2019 | 141 | 2019 |
| Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates O Humbert, S Radtke, C Samuelson, RR Carrillo, AM Perez, SS Reddy, ... Science translational medicine 11 (503), eaaw3768, 2019 | 107 | 2019 |
| Current views on tumor mutational burden in patients with non-small cell lung cancer treated by immune checkpoint inhibitors L Berland, S Heeke, O Humbert, A Macocco, E Long-Mira, S Lassalle, ... Journal of thoracic disease 11 (Suppl 1), S71, 2019 | 83 | 2019 |
| Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks R Kuhar, KS Gwiazda, O Humbert, T Mandt, J Pangallo, M Brault, I Khan, ... Nucleic acids research 42 (1), e4-e4, 2014 | 76 | 2014 |
| Targeted gene therapies: tools, applications, optimization O Humbert, L Davis, N Maizels Critical reviews in biochemistry and molecular biology 47 (3), 264-281, 2012 | 70 | 2012 |
| Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates CW Peterson, J Wang, KK Norman, ZK Norgaard, O Humbert, CK Tse, ... Blood, The Journal of the American Society of Hematology 127 (20), 2416-2426, 2016 | 68 | 2016 |
| Engineering resistance to CD33-targeted immunotherapy in normal hematopoiesis by CRISPR/Cas9-deletion of CD33 exon 2 O Humbert, GS Laszlo, S Sichel, C Ironside, KG Haworth, OM Bates, ... Leukemia 33 (3), 762-808, 2019 | 64 | 2019 |
| Characterization of Helicobacter pylori factors that control transformation frequency and integration length during inter‐strain DNA recombination O Humbert, MS Dorer, NR Salama Molecular microbiology 79 (2), 387-401, 2011 | 63 | 2011 |
| Trafficking of Superinfecting Mycobacterium Organisms into Established Granulomas Occurs in Mammals and Is Independent of the Erp and ESX-1 Mycobacterial … CL Cosma, O Humbert, DR Sherman, L Ramakrishnan The Journal of infectious diseases 198 (12), 1851-1855, 2008 | 62 | 2008 |
| The Helicobacter pylori HpyAXII restriction–modification system limits exogenous DNA uptake by targeting GTAC sites but shows asymmetric … O Humbert, NR Salama Nucleic acids research 36 (21), 6893-6906, 2008 | 56 | 2008 |
| TALEN-mediated gene editing of HBG in human hematopoietic stem cells leads to therapeutic fetal hemoglobin induction CT Lux, S Pattabhi, M Berger, C Nourigat, DA Flowers, O Negre, ... Molecular Therapy-Methods & Clinical Development 12, 175-183, 2019 | 54 | 2019 |
| A nonhuman primate transplantation model to evaluate hematopoietic stem cell gene editing strategies for β-hemoglobinopathies O Humbert, CW Peterson, ZK Norgaard, S Radtke, HP Kiem Molecular Therapy Methods & Clinical Development 8, 75-86, 2018 | 44 | 2018 |
| Development of third-generation cocal envelope producer cell lines for robust lentiviral gene transfer into hematopoietic stem cells and T-cells O Humbert, DW Gisch, ME Wohlfahrt, AB Adams, PD Greenberg, ... Molecular Therapy 24 (7), 1237-1246, 2016 | 44 | 2016 |
| Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ... Nature biotechnology 40 (7), 1103-1113, 2022 | 39 | 2022 |
| Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations C Samuelson, S Radtke, H Zhu, M Llewellyn, E Fields, S Cook, ... Molecular Therapy-Methods & Clinical Development 23, 507-523, 2021 | 29 | 2021 |
