Comparative flavivirus-host protein interaction mapping reveals mechanisms of dengue and Zika virus pathogenesis PS Shah, N Link, GM Jang, PP Sharp, T Zhu, DL Swaney, JR Johnson, ... Cell 175 (7), 1931-1945. e18, 2018 | 283 | 2018 |
Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling RS Ashton, A Conway, C Pangarkar, J Bergen, KI Lim, P Shah, M Bissell, ... Nature neuroscience 15 (10), 1399-1406, 2012 | 261 | 2012 |
The dengue virus NS5 protein intrudes in the cellular spliceosome and modulates splicing FA De Maio, G Risso, NG Iglesias, P Shah, B Pozzi, LG Gebhard, ... PLoS pathogens 12 (8), e1005841, 2016 | 200 | 2016 |
A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay HR Ramage, GR Kumar, E Verschueren, JR Johnson, J Von Dollen, ... Molecular cell 57 (2), 329-340, 2015 | 146 | 2015 |
Control of stochastic gene expression by host factors at the HIV promoter JC Burnett, K Miller-Jensen, PS Shah, AP Arkin, DV Schaffer PLoS pathogens 5 (1), e1000260, 2009 | 140 | 2009 |
Targeting viral proteostasis limits influenza virus, HIV, and dengue virus infection NS Heaton, N Moshkina, R Fenouil, TJ Gardner, S Aguirre, PS Shah, ... Immunity 44 (1), 46-58, 2016 | 132 | 2016 |
Mutations in ANKLE2, a ZIKA virus target, disrupt an asymmetric cell division pathway in Drosophila neuroblasts to cause microcephaly N Link, H Chung, A Jolly, M Withers, B Tepe, BR Arenkiel, PS Shah, ... Developmental cell 51 (6), 713-729. e6, 2019 | 83 | 2019 |
Multiple routes to oncogenesis are promoted by the human papillomavirus–host protein network M Eckhardt, W Zhang, AM Gross, J Von Dollen, JR Johnson, ... Cancer discovery 8 (11), 1474-1489, 2018 | 80 | 2018 |
The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein KA Fontaine, KE Leon, MM Khalid, S Tomar, D Jimenez-Morales, ... MBio 9 (6), 10.1128/mbio. 02126-18, 2018 | 66* | 2018 |
Identification of antiviral roles for the exon–junction complex and nonsense-mediated decay in flaviviral infection M Li, JR Johnson, B Truong, G Kim, N Weinbren, M Dittmar, PS Shah, ... Nature microbiology 4 (6), 985-995, 2019 | 65 | 2019 |
HIV evades RNA interference directed at TAR by an indirect compensatory mechanism JN Leonard, PS Shah, JC Burnett, DV Schaffer Cell host & microbe 4 (5), 484-494, 2008 | 59 | 2008 |
Contributions of the international plant science community to the fight against human infectious diseases–part 1: epidemic and pandemic diseases M Lobato Gomez, X Huang, D Alvarez, W He, C Baysal, C Zhu, ... Plant biotechnology journal 19 (10), 1901-1920, 2021 | 46 | 2021 |
Compositions and methods for treating Dengue virus infection M Ott, AS Kondratowicz, NJ Krogan, PS Shah, KA Fontaine US Patent 10,004,751, 2018 | 46* | 2018 |
Comparative mapping of host–pathogen protein–protein interactions PS Shah, JA Wojcechowskyj, M Eckhardt, NJ Krogan Current opinion in microbiology 27, 62-68, 2015 | 39 | 2015 |
Genetic selection for context-dependent stochastic phenotypes: Sp1 and TATA mutations increase phenotypic noise in HIV-1 gene expression K Miller-Jensen, R Skupsky, PS Shah, AP Arkin, DV Schaffer PLoS computational biology 9 (7), e1003135, 2013 | 39 | 2013 |
HIV develops indirect cross-resistance to combinatorial RNAi targeting two distinct and spatially distant sites PS Shah, NP Pham, DV Schaffer Molecular Therapy 20 (4), 840-848, 2012 | 32 | 2012 |
Contributions of the international plant science community to the fight against infectious diseases in humans—part 2: Affordable drugs in edible plants for endemic and re … W He, C Baysal, M Lobato Gómez, X Huang, D Alvarez, C Zhu, ... Plant biotechnology journal 19 (10), 1921-1936, 2021 | 31 | 2021 |
SARS-CoV-2 spike binding to ACE2 is stronger and longer ranged due to glycan interaction Y Huang, BS Harris, SA Minami, S Jung, PS Shah, S Nandi, KA McDonald, ... Biophysical journal 121 (1), 79-90, 2022 | 29 | 2022 |
Computational models of HIV-1 resistance to gene therapy elucidate therapy design principles S Aviran, PS Shah, DV Schaffer, AP Arkin PLoS computational biology 6 (8), e1000883, 2010 | 26 | 2010 |
Nuclear dengue virus NS5 antagonizes expression of PAF1-dependent immune response genes MJ Petit, MW Kenaston, OH Pham, AA Nagainis, AT Fishburn, PS Shah PLoS pathogens 17 (11), e1010100, 2021 | 24 | 2021 |