Withanone from Withania somnifera may inhibit novel coronavirus (COVID-19) entry by disrupting interactions between viral S-protein receptor binding domain and host ACE2 receptor A Balkrishna, S Pokhrel, J Singh, A Varshney | 90 | 2020 |
Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized … A Balkrishna, S Pokhrel, H Singh, M Joshi, VP Mulay, S Haldar, ... Drug design, development and therapy, 1111-1133, 2021 | 87 | 2021 |
Thermostabilization of Bacillus circulans xylanase via computational design of a flexible surface cavity JC Joo, S Pohkrel, SP Pack, YJ Yoo Journal of biotechnology 146 (1-2), 31-39, 2010 | 77 | 2010 |
Anti-acetylcholinesterase activities of mono-herbal extracts and exhibited synergistic effects of the phytoconstituents: A biochemical and computational study A Balkrishna, S Pokhrel, M Tomer, S Verma, A Kumar, P Nain, A Gupta, ... Molecules 24 (22), 4175, 2019 | 58 | 2019 |
Colchicine: Isolation, LC–MS QTof Screening, and Anticancer Activity Study of Gloriosa superba Seeds A Balkrishna, SK Das, S Pokhrel, A Joshi, Laxmi, S Verma, VK Sharma, ... Molecules 24 (15), 2772, 2019 | 39 | 2019 |
Shifting the optimum pH of Bacillus circulans xylanase towards acidic side by introducing arginine S Pokhrel, JC Joo, YJ Yoo Biotechnology and bioprocess engineering 18, 35-42, 2013 | 36 | 2013 |
Tinocordiside from Tinospora cordifolia (Giloy) may curb SARS-CoV-2 contagion by disrupting the electrostatic interactions between host ACE2 and viral S-protein receptor … A Balkrishna, S Pokhrel, A Varshney Combinatorial Chemistry & High Throughput Screening 24 (10), 1795-1802, 2021 | 32 | 2021 |
Mutation of non-conserved amino acids surrounding catalytic site to shift pH optimum of Bacillus circulans xylanase SH Kim, S Pokhrel, YJ Yoo Journal of Molecular Catalysis B: Enzymatic 55 (3-4), 130-136, 2008 | 32 | 2008 |
Rational design of a Bacillus circulans xylanase by introducing charged residue to shift the pH optimum S Pokhrel, JC Joo, YH Kim, YJ Yoo Process Biochemistry 47 (12), 2487-2493, 2012 | 29 | 2012 |
Utility of gamma-glutamyl transpeptidase and mean corpuscular volume in alcoholic liver disease N Baral, S Pokhrel, M Lamsal, BN Yadav, SP Sah Southeast Asian journal of tropical medicine and public health 36 (4), 1007, 2005 | 17 | 2005 |
Thermostable glucose isomerase from psychrotolerant Streptomyces species B Dhungel, M Subedi, KB Tiwari, UT Shrestha, S Pokhrel, VP Agrawal International Journal of Life Sciences 1, 6-10, 2007 | 16 | 2007 |
Tinospora cordifolia (Giloy) may curb COVID-19 contagion: tinocordiside disrupts the electrostatic interactions between ACE2 and RBD A Balkrishna, S POKHREL, A Varshney Authorea Preprints, 2020 | 7 | 2020 |
Enzymatic analysis of the effect of naturally occurring Leu138Pro mutation identified in SHV β-lactamase on hydrolysis of penicillin and ampicillin N Rayamajhi, JC Joo, SB Cha, S Pokherl, MK Shin, YJ Yoo, HS Yoo BMC microbiology 11, 1-7, 2011 | 7 | 2011 |
Age related changes in cholesterol level among the patients with subclinical hypothyroidism in eastern Nepal. S Pokhrel, N Baral, MG Sridhar, M Lamsal Nepal Medical College Journal: NMCJ 8 (3), 185-189, 2006 | 6 | 2006 |
Old-aged, adolescent and pregnant women in eastern Nepal are more prone to subclinical hypothyroidism: a hospital based retrospec ve study RL Mallick, SJ Walavalkar, S Pokhrel, RK Singh Intl J Pharm and Biol Arch 19 (1), 1-7, 2016 | 5 | 2016 |
Activity enhancement of a Bacillus circulans xylanase by introducing ion-pair interactions into an α-helix S Pokhrel, JC Joo, HS Lee, YJ Yoo Process Biochemistry 48 (10), 1495-1501, 2013 | 5 | 2013 |
Designing active site pKa values to shift optimum pH of Bacillus circulans xylanase S Pokhrel, YJ Yoo New Biotechnology 25, S126, 2009 | 5 | 2009 |
Divya-Arjuna-Kwath (Terminalia arjuna) and Divya-HridyAmrit-Vati ameliorate isoproterenol-induced hypertrophy in murine cardiomyocytes through modulation of oxidative stress A Balkrishna, Y Rustagi, M Tomer, S Pokhrel, K Bhattacharya, A Varshney Phytomedicine Plus 1 (4), 100074, 2021 | 4 | 2021 |
Phyto-compounds from a rather poisonous plant, Strychnos nuxvomica, show high potency against SARS-CoV-2 RNA-dependent RNA polymerase A Balkrishna, S Pokhrel, A Varshney Current Molecular Medicine 22 (10), 929-940, 2022 | 3 | 2022 |
Strong mosquitocidal Bacillus thuringiensis from Mt. Everest UT Shrestha, GS Shahukhal, KB Tiwari, S Pokhrel, A Singh, VP Agrawal Our Nature 5 (1), 67-69, 2007 | 3 | 2007 |