PROTAC: an effective targeted protein degradation strategy for cancer therapy SM Qi, J Dong, ZY Xu, XD Cheng, WD Zhang, JJ Qin Frontiers in Pharmacology 12, 692574, 2021 | 184 | 2021 |
Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update J Dong, Z Qin, WD Zhang, G Cheng, AG Yehuda, CR Ashby Jr, ZS Chen, ... Drug Resistance Updates 49, 100681, 2020 | 174 | 2020 |
Recent advances in the development of indazole‐based anticancer agents J Dong, Q Zhang, Z Wang, G Huang, S Li ChemMedChem 13 (15), 1490-1507, 2018 | 114 | 2018 |
Recent update on development of small-molecule STAT3 inhibitors for cancer therapy: from phosphorylation inhibition to protein degradation J Dong, XD Cheng, WD Zhang, JJ Qin Journal of Medicinal Chemistry 64 (13), 8884-8915, 2021 | 104 | 2021 |
Biphenyl derivatives incorporating urea unit as novel VEGFR-2 inhibitors: design, synthesis and biological evaluation C Wang, H Gao, J Dong, Y Zhang, P Su, Y Shi, J Zhang Bioorganic & Medicinal Chemistry 22 (1), 277-284, 2014 | 56 | 2014 |
Protein degradation technology: a strategic paradigm shift in drug discovery H Li, J Dong, M Cai, Z Xu, XD Cheng, JJ Qin Journal of Hematology & Oncology 14, 1-23, 2021 | 51 | 2021 |
Flavonoids and naphthoflavonoids: wider roles in the modulation of cytochrome P450 family 1 enzymes J Dong, Q Zhang, Q Cui, G Huang, X Pan, S Li ChemMedChem 11 (19), 2102-2118, 2016 | 48 | 2016 |
Discovery of novel VEGFR-2 inhibitors. Part II: Biphenyl urea incorporated with salicylaldoxime H Gao, P Su, Y Shi, X Shen, Y Zhang, J Dong, J Zhang European Journal of Medicinal Chemistry 90, 232-240, 2015 | 46 | 2015 |
Development of novel ferulic acid derivatives as potent histone deacetylase inhibitors F Wang, W Lu, T Zhang, J Dong, H Gao, P Li, S Wang, J Zhang Bioorganic & medicinal chemistry 21 (22), 6973-6980, 2013 | 41 | 2013 |
Synthesis and biological evaluation of sulfur-containing shikonin oxime derivatives as potential antineoplastic agents G Huang, HR Zhao, QQ Meng, QJ Zhang, JY Dong, B Zhu, SS Li European Journal of Medicinal Chemistry 143, 166-181, 2018 | 39 | 2018 |
Antimicrobial peptide reverses ABCB1-mediated chemotherapeutic drug resistance X Luo, QX Teng, JY Dong, DH Yang, M Wang, W Dessie, JJ Qin, ZN Lei, ... Frontiers in Pharmacology 11, 1208, 2020 | 30 | 2020 |
Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors J Dong, Z Wang, J Cui, Q Meng, S Li European journal of medicinal chemistry 187, 111938, 2020 | 29 | 2020 |
Design, synthesis and biological evaluation of biphenyl urea derivatives as novel VEGFR-2 inhibitors C Wang, J Dong, Y Zhang, F Wang, H Gao, P Li, S Wang, J Zhang MedChemComm 4 (11), 1434-1438, 2013 | 27 | 2013 |
Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors J Dong, G Huang, Q Cui, Q Meng, S Li, J Cui European Journal of Medicinal Chemistry 209, 112895, 2021 | 25 | 2021 |
Expanding the structural diversity of Bcr-Abl inhibitors: Dibenzoylpiperazin incorporated with 1H-indazol-3-amine Y Shan, J Dong, X Pan, L Zhang, J Zhang, Y Dong, M Wang European Journal of Medicinal Chemistry 104, 139-147, 2015 | 25 | 2015 |
The chemistry and biological effects of thioflavones J Dong, Q Zhang, Q Meng, Z Wang, S Li, J Cui Mini reviews in medicinal chemistry 18 (20), 1714-1732, 2018 | 24 | 2018 |
Development of benzochalcone derivatives as selective CYP1B1 inhibitors and anticancer agents J Dong, G Huang, Q Zhang, Z Wang, J Cui, Y Wu, Q Meng, S Li MedChemComm 10 (9), 1606-1614, 2019 | 23 | 2019 |
Design, synthesis, and biological evaluation of cytochrome P450 1B1 targeted molecular imaging probes for colorectal tumor detection Q Meng, Z Wang, J Cui, Q Cui, J Dong, Q Zhang, S Li Journal of Medicinal Chemistry 61 (23), 10901-10909, 2018 | 21 | 2018 |
Cytotoxicity of synthesized 1, 4-naphthoquinone oxime derivatives on selected human cancer cell lines Q Zhang, J Dong, J Cui, G Huang, Q Meng, S Li Chemical and Pharmaceutical Bulletin 66 (6), 612-619, 2018 | 20 | 2018 |
Polyphyllin B suppresses gastric tumor growth by modulating iron metabolism and inducing ferroptosis C Hu, D Zu, J Xu, H Xu, L Yuan, J Chen, Q Wei, Y Zhang, J Han, T Lu, ... International Journal of Biological Sciences 19 (4), 1063, 2023 | 19 | 2023 |