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Jinyun Dong
Jinyun Dong
中国科学院杭州医学研究所
在 sjtu.edu.cn 的电子邮件经过验证
标题
引用次数
引用次数
年份
PROTAC: an effective targeted protein degradation strategy for cancer therapy
SM Qi, J Dong, ZY Xu, XD Cheng, WD Zhang, JJ Qin
Frontiers in Pharmacology 12, 692574, 2021
1842021
Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update
J Dong, Z Qin, WD Zhang, G Cheng, AG Yehuda, CR Ashby Jr, ZS Chen, ...
Drug Resistance Updates 49, 100681, 2020
1742020
Recent advances in the development of indazole‐based anticancer agents
J Dong, Q Zhang, Z Wang, G Huang, S Li
ChemMedChem 13 (15), 1490-1507, 2018
1142018
Recent update on development of small-molecule STAT3 inhibitors for cancer therapy: from phosphorylation inhibition to protein degradation
J Dong, XD Cheng, WD Zhang, JJ Qin
Journal of Medicinal Chemistry 64 (13), 8884-8915, 2021
1042021
Biphenyl derivatives incorporating urea unit as novel VEGFR-2 inhibitors: design, synthesis and biological evaluation
C Wang, H Gao, J Dong, Y Zhang, P Su, Y Shi, J Zhang
Bioorganic & Medicinal Chemistry 22 (1), 277-284, 2014
562014
Protein degradation technology: a strategic paradigm shift in drug discovery
H Li, J Dong, M Cai, Z Xu, XD Cheng, JJ Qin
Journal of Hematology & Oncology 14, 1-23, 2021
512021
Flavonoids and naphthoflavonoids: wider roles in the modulation of cytochrome P450 family 1 enzymes
J Dong, Q Zhang, Q Cui, G Huang, X Pan, S Li
ChemMedChem 11 (19), 2102-2118, 2016
482016
Discovery of novel VEGFR-2 inhibitors. Part II: Biphenyl urea incorporated with salicylaldoxime
H Gao, P Su, Y Shi, X Shen, Y Zhang, J Dong, J Zhang
European Journal of Medicinal Chemistry 90, 232-240, 2015
462015
Development of novel ferulic acid derivatives as potent histone deacetylase inhibitors
F Wang, W Lu, T Zhang, J Dong, H Gao, P Li, S Wang, J Zhang
Bioorganic & medicinal chemistry 21 (22), 6973-6980, 2013
412013
Synthesis and biological evaluation of sulfur-containing shikonin oxime derivatives as potential antineoplastic agents
G Huang, HR Zhao, QQ Meng, QJ Zhang, JY Dong, B Zhu, SS Li
European Journal of Medicinal Chemistry 143, 166-181, 2018
392018
Antimicrobial peptide reverses ABCB1-mediated chemotherapeutic drug resistance
X Luo, QX Teng, JY Dong, DH Yang, M Wang, W Dessie, JJ Qin, ZN Lei, ...
Frontiers in Pharmacology 11, 1208, 2020
302020
Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors
J Dong, Z Wang, J Cui, Q Meng, S Li
European journal of medicinal chemistry 187, 111938, 2020
292020
Design, synthesis and biological evaluation of biphenyl urea derivatives as novel VEGFR-2 inhibitors
C Wang, J Dong, Y Zhang, F Wang, H Gao, P Li, S Wang, J Zhang
MedChemComm 4 (11), 1434-1438, 2013
272013
Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors
J Dong, G Huang, Q Cui, Q Meng, S Li, J Cui
European Journal of Medicinal Chemistry 209, 112895, 2021
252021
Expanding the structural diversity of Bcr-Abl inhibitors: Dibenzoylpiperazin incorporated with 1H-indazol-3-amine
Y Shan, J Dong, X Pan, L Zhang, J Zhang, Y Dong, M Wang
European Journal of Medicinal Chemistry 104, 139-147, 2015
252015
The chemistry and biological effects of thioflavones
J Dong, Q Zhang, Q Meng, Z Wang, S Li, J Cui
Mini reviews in medicinal chemistry 18 (20), 1714-1732, 2018
242018
Development of benzochalcone derivatives as selective CYP1B1 inhibitors and anticancer agents
J Dong, G Huang, Q Zhang, Z Wang, J Cui, Y Wu, Q Meng, S Li
MedChemComm 10 (9), 1606-1614, 2019
232019
Design, synthesis, and biological evaluation of cytochrome P450 1B1 targeted molecular imaging probes for colorectal tumor detection
Q Meng, Z Wang, J Cui, Q Cui, J Dong, Q Zhang, S Li
Journal of Medicinal Chemistry 61 (23), 10901-10909, 2018
212018
Cytotoxicity of synthesized 1, 4-naphthoquinone oxime derivatives on selected human cancer cell lines
Q Zhang, J Dong, J Cui, G Huang, Q Meng, S Li
Chemical and Pharmaceutical Bulletin 66 (6), 612-619, 2018
202018
Polyphyllin B suppresses gastric tumor growth by modulating iron metabolism and inducing ferroptosis
C Hu, D Zu, J Xu, H Xu, L Yuan, J Chen, Q Wei, Y Zhang, J Han, T Lu, ...
International Journal of Biological Sciences 19 (4), 1063, 2023
192023
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