| iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy D Brücher, N Kirchhammer, SN Smith, J Schumacher, N Schumacher, ... Molecular Therapy-Methods & Clinical Development 20, 572-586, 2021 | 27 | 2021 |
| The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody SN Smith, R Schubert, B Simic, D Brücher, M Schmid, N Kirk, PC Freitag, ... Proceedings of the National Academy of Sciences 118 (21), e2017925118, 2021 | 22 | 2021 |
| Unravelling receptor and RGD motif dependence of retargeted adenoviral vectors using advanced tumor model systems M Chernyavska, M Schmid, PC Freitag, V Palacio-Castañeda, A Piruska, ... Scientific reports 9 (1), 18568, 2019 | 21 | 2019 |
| Programmable DARPin-based receptors for the detection of thrombotic markers T Strittmatter, Y Wang, A Bertschi, L Scheller, PC Freitag, PG Ray, ... Nature chemical biology 18 (10), 1125-1134, 2022 | 13 | 2022 |
| Modular adapters utilizing binders of different molecular types expand cell-targeting options for adenovirus gene delivery PC Freitag, F Brandl, D Brücher, F Weiss, B Dreier, A Plückthun Bioconjugate Chemistry 33 (9), 1595-1601, 2022 | 9 | 2022 |
| Targeted adenovirus-mediated transduction of human T cells in vitro and in vivo PC Freitag, M Kaulfuss, L Flühler, J Mietz, F Weiss, D Brücher, J Kolibius, ... Molecular Therapy Methods & Clinical Development 29, 120-132, 2023 | 8 | 2023 |
| Targeted shock-and-kill HIV-1 gene therapy approach combining CRISPR activation, suicide gene tBid and retargeted adenovirus delivery S Klinnert, CD Schenkel, PC Freitag, HF Günthard, A Plückthun, ... Gene Therapy 31 (3), 74-84, 2024 | 6 | 2024 |
| FAP-retargeted Ad5 enables in vivo gene delivery to stromal cells in the tumor microenvironment KP Hartmann, M van Gogh, PC Freitag, F Kast, G Nagy-Davidescu, ... Molecular Therapy 31 (10), 2914-2928, 2023 | 5 | 2023 |
| DARPin-fused T cell engager for adenovirus-mediated cancer therapy PC Freitag, J Kolibius, R Wieboldt, R Weber, KP Hartmann, M van Gogh, ... Molecular Therapy Oncology, 2024 | | 2024 |
| Dendritic cell targeting in lymph nodes with engineered modular adapters improves HAdV5 and HC-HAdV5 tumor vaccination by co-secretion of IL-2v and IL-21 F Weiss, J Kolibius, PC Freitag, F Gantenbein, A Kipar, A Plueckthun bioRxiv, 2024.04. 27.591433, 2024 | | 2024 |
| Adapter Development for Targeted Adenoviral-Mediated Engineering of Human T Cells in Vitro and In Vivo PC Freitag University of Zurich, 2023 | | 2023 |
| Targeting HIV-1 with CRISPR/Cas9 delivered by retargeted adenoviruses effectively suppresses viral replication S Klinnert, PC Freitag, A Plueckthun, KJ Metzner bioRxiv, 2023.12. 18.572146, 2023 | | 2023 |
| Engineering adenoviral vectors for a targeted delivery of therapeutic payloads KP Hartmann, M Van Gogh, G Nagy-Davidescu, PC Freitag, A Plueckthun HUMAN GENE THERAPY 33 (23-24), A56-A57, 2022 | | 2022 |
| Zellspezifische Produktion von multiplen Therapeutika im Körper D Brücher, PC Freitag, A Plückthun BIOspektrum 28 (2), 155-158, 2022 | | 2022 |
Andreas PluckthunBiochemisches Institut, Universität Zürich在 bioc.uzh.ch 的电子邮件经过验证
Andreas PluckthunBiochemisches Institut, Universität Zürich在 bioc.uzh.ch 的电子邮件经过验证
Wouter P.R. VerdurmenAssistant Professor, Radboud University Medical Center在 radboudumc.nl 的电子邮件经过验证