| Structure and function of legumain in health and disease E Dall, H Brandstetter Biochimie 122, 126-150, 2016 | 285 | 2016 |
| Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation E Dall, H Brandstetter Proceedings of the National Academy of Sciences 110 (27), 10940-10945, 2013 | 215 | 2013 |
| Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer’s disease Z Zhang, O Obianyo, E Dall, Y Du, H Fu, X Liu, SS Kang, M Song, SP Yu, ... Nature communications 8 (1), 14740, 2017 | 122 | 2017 |
| Activation of legumain involves proteolytic and conformational events, resulting in a context-and substrate-dependent activity profile E Dall, H Brandstetter Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 103 | 2012 |
| Structure and mechanism of an aspartimide‐dependent peptide ligase in human legumain E Dall, JC Fegg, P Briza, H Brandstetter Angewandte Chemie International Edition 54 (10), 2917-2921, 2015 | 97 | 2015 |
| Crystal structure of plant legumain reveals a unique two-chain state with pH-dependent activity regulation FB Zauner, E Dall, C Regl, L Grassi, CG Huber, C Cabrele, H Brandstetter The Plant Cell 30 (3), 686-699, 2018 | 83 | 2018 |
| Distinct roles of catalytic cysteine and histidine in the protease and ligase mechanisms of human legumain as revealed by DFT-based QM/MM simulations B Elsässer, FB Zauner, J Messner, WT Soh, E Dall, H Brandstetter ACS catalysis 7 (9), 5585-5593, 2017 | 58 | 2017 |
| Structural analyses of Arabidopsis thaliana legumain γ reveal differential recognition and processing of proteolysis and ligation substrates FB Zauner, B Elsässer, E Dall, C Cabrele, H Brandstetter Journal of Biological Chemistry 293 (23), 8934-8946, 2018 | 53 | 2018 |
| Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity R Freier, E Dall, H Brandstetter Scientific reports 5 (1), 12707, 2015 | 44 | 2015 |
| Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition E Dall, FB Zauner, WT Soh, F Demir, SO Dahms, C Cabrele, PF Huesgen, ... Journal of Biological Chemistry 295 (37), 13047-13064, 2020 | 32 | 2020 |
| Structural and functional analysis of cystatin E reveals enzymologically relevant dimer and amyloid fibril states E Dall, JC Hollerweger, SO Dahms, H Cui, K Häussermann, ... Journal of Biological Chemistry 293 (34), 13151-13165, 2018 | 25 | 2018 |
| Laser‐facilitated epicutaneous immunotherapy with hypoallergenic beta‐glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of … E Korotchenko, V Schießl, S Scheiblhofer, M Schubert, E Dall, IA Joubert, ... Allergy 76 (1), 210-222, 2021 | 24 | 2021 |
| Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design E Barbosa da Silva, E Dall, P Briza, H Brandstetter, RS Ferreira Acta Crystallographica Section F: Structural Biology Communications 75 (6 …, 2019 | 20 | 2019 |
| ExteNDing proteome coverage with legumain as a highly specific digestion protease WT Soh, F Demir, E Dall, A Perrar, SO Dahms, M Kuppusamy, ... Analytical chemistry 92 (4), 2961-2971, 2020 | 19 | 2020 |
| The peptide ligase activity of human legumain depends on fold stabilization and balanced substrate affinities E Dall, V Stanojlovic, F Demir, P Briza, SO Dahms, PF Huesgen, ... ACS catalysis 11 (19), 11885-11896, 2021 | 16 | 2021 |
| Two distinct conformations in Bet v 2 determine its proteolytic resistance to cathepsin S WT Soh, P Briza, E Dall, C Asam, M Schubert, S Huber, L Aglas, B Bohle, ... International journal of molecular sciences 18 (10), 2156, 2017 | 9 | 2017 |
| Production of Functional Plant Legumain Proteases Using the Leishmania tarentolae Expression System E Dall, A Licht, H Brandstetter Plant Proteases and Plant Cell Death: Methods and Protocols, 35-51, 2022 | 6 | 2022 |
| Comparing proteolytic fingerprints of antigen-presenting cells during allergen processing H Hofer, T Weidinger, P Briza, C Asam, M Wolf, TE Twaroch, F Stolz, ... International journal of molecular sciences 18 (6), 1225, 2017 | 6 | 2017 |
| Legumain Activity Is Controlled by Extended Active Site Residues and Substrate Conformation T Elamin, H Brandstetter, E Dall International Journal of Molecular Sciences 23 (20), 12548, 2022 | 4 | 2022 |
| Phytocystatin 6 is a context‐dependent, tight‐binding inhibitor of Arabidopsis thaliana legumain isoform β NP Santos, WT Soh, F Demir, R Tenhaken, P Briza, PF Huesgen, ... The Plant Journal 116 (6), 1681-1695, 2023 | 3 | 2023 |
