Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex MA McDowell, M Heimes, F Fiorentino, S Mehmood, Á Farkas, ... Molecular Cell 80 (1), 72-86. e7, 2020 | 87 | 2020 |
Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide F Fiorentino, JB Sauer, X Qiu, RA Corey, CK Cassidy, B Mynors-Wallis, ... Nature Chemical Biology 17 (2), 187-195, 2021 | 52 | 2021 |
Emerging Therapeutic Potential of SIRT6 Modulators F Fiorentino, A Mai, D Rotili Journal of Medicinal Chemistry 64 (14), 9732-9758, 2021 | 50 | 2021 |
Assembly and regulation of the chlorhexidine-specific efflux pump AceI JR Bolla, AC Howes, F Fiorentino, CV Robinson Proceedings of the National Academy of Sciences 117 (29), 17011-17018, 2020 | 45 | 2020 |
The Two-Faced Role of SIRT6 in Cancer F Fiorentino, V Carafa, G Favale, L Altucci, A Mai, D Rotili Cancers 13 (5), 1156, 2021 | 44 | 2021 |
Sirtuin modulators: past, present, and future perspectives F Fiorentino, N Mautone, M Menna, F D'Acunzo, A Mai, D Rotili Future Medicinal Chemistry 14 (12), 915-939, 2022 | 36 | 2022 |
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey F Fiorentino, M Menna, D Rotili, S Valente, A Mai Journal of Medicinal Chemistry 66 (3), 1654-1677, 2023 | 31 | 2023 |
Lysine acetyltransferase inhibitors: structure–activity relationships and potential therapeutic implications F Fiorentino, A Mai, D Rotili Future medicinal chemistry 10 (9), 1067-1091, 2018 | 29 | 2018 |
Lysine Acetyltransferase Inhibitors From Natural Sources F Fiorentino, A Mai, D Rotili Frontiers in Pharmacology 11, 1243, 2020 | 26 | 2020 |
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 F Fiorentino, C Castiello, A Mai, D Rotili Journal of Medicinal Chemistry 65 (14), 9580-9606, 2022 | 25 | 2022 |
The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters F Fiorentino, JR Bolla, S Mehmood, CV Robinson Structure 27 (4), 651-659. e3, 2019 | 24 | 2019 |
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription M Minisini, E Di Giorgio, E Kerschbamer, E Dalla, M Faggiani, E Franforte, ... Nucleic acids research 50 (5), 2566-2586, 2022 | 16 | 2022 |
Rationalizing the Optimization of Detergents for Membrane Protein Purification LH Urner, F Junge, F Fiorentino, TJ El‐Baba, D Shutin, G Nölte, R Haag, ... Chemistry–A European Journal 29 (30), e202300159, 2023 | 15 | 2023 |
Mass spectrometry informs the structure and dynamics of membrane proteins involved in lipid and drug transport JR Bolla, F Fiorentino, CV Robinson Current Opinion in Structural Biology 70, 53-60, 2021 | 15 | 2021 |
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models M Menna, F Fiorentino, B Marrocco, A Lucidi, S Tomassi, D Cilli, ... European Journal of Medicinal Chemistry 237, 114410, 2022 | 14 | 2022 |
Biochemical Functions and Clinical Characterizations of the Sirtuins in Diabetes-Induced Retinal Pathologies S Taurone, C De Ponte, D Rotili, E De Santis, A Mai, F Fiorentino, ... International Journal of Molecular Sciences 23 (7), 4048, 2022 | 13 | 2022 |
NaViA: a program for the visual analysis of complex mass spectra D Quetschlich, TK Esser, TD Newport, F Fiorentino, D Shutin, S Chen, ... Bioinformatics 37 (24), 4876-4878, 2021 | 13 | 2021 |
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection E Fabbrizi, F Fiorentino, V Carafa, L Altucci, A Mai, D Rotili Cells 12 (6), 852, 2023 | 12 | 2023 |
Anionic Dendritic Polyglycerol for Protein Purification and Delipidation LH Urner, E Mohammadifar, K Ludwig, D Shutin, F Fiorentino, I Liko, ... ACS Applied Polymer Materials 3 (11), 5903-5911, 2021 | 12 | 2021 |
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions F Fiorentino, D Rotili, A Mai, JR Bolla, CV Robinson Chemical Communications 57 (82), 10747-10750, 2021 | 9 | 2021 |