Ca2+ hot spots on the mitochondrial surface are generated by Ca2+ mobilization from stores, but not by activation of store-operated Ca2+ channels M Giacomello, I Drago, M Bortolozzi, M Scorzeto, A Gianelle, P Pizzo, ... Molecular cell 38 (2), 280-290, 2010 | 432 | 2010 |
Presenilin 2 modulates endoplasmic reticulum (ER)–mitochondria interactions and Ca2+ cross-talk E Zampese, C Fasolato, MJ Kipanyula, M Bortolozzi, T Pozzan, P Pizzo Proceedings of the National Academy of Sciences 108 (7), 2777-2782, 2011 | 307 | 2011 |
A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function M Spinazzi, S Cazzola, M Bortolozzi, A Baracca, E Loro, A Casarin, ... Human molecular genetics 17 (21), 3291-3302, 2008 | 139 | 2008 |
A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness R Ficarella, F Di Leva, M Bortolozzi, S Ortolano, F Donaudy, M Petrillo, ... Proceedings of the National Academy of Sciences 104 (5), 1516-1521, 2007 | 134 | 2007 |
The antidiabetic drug metformin blunts NETosis in vitro and reduces circulating NETosis biomarkers in vivo L Menegazzo, V Scattolini, R Cappellari, BM Bonora, M Albiero, ... Acta Diabetologica 55, 593-601, 2018 | 133 | 2018 |
PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling S Monterisi, MJ Lobo, C Livie, JC Castle, M Weinberger, G Baillie, ... elife 6, e21374, 2017 | 110 | 2017 |
ATP-mediated cell–cell signaling in the organ of Corti: the role of connexin channels P Majumder, G Crispino, L Rodriguez, CD Ciubotaru, F Anselmi, V Piazza, ... Purinergic signalling 6, 167-187, 2010 | 100 | 2010 |
Unitary permeability of gap junction channels to second messengers measured by FRET microscopy VH Hernandez, M Bortolozzi, V Pertegato, M Beltramello, M Giarin, ... Nature Methods 4 (4), 353-358, 2007 | 83 | 2007 |
BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice G Crispino, G Di Pasquale, P Scimemi, L Rodriguez, F Galindo Ramirez, ... PloS one 6 (8), e23279, 2011 | 79 | 2011 |
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice M Schuetz, P Scimemi, P Majumder, RD De Siati, G Crispino, L Rodriguez, ... Human molecular genetics 19 (24), 4759-4773, 2010 | 79 | 2010 |
Ca2+ Signaling in the Inner Ear F Mammano, M Bortolozzi, S Ortolano, F Anselmi Physiology 22 (2), 131-144, 2007 | 74 | 2007 |
The Novel Mouse Mutation Oblivion Inactivates the PMCA2 Pump and Causes Progressive Hearing Loss SL Spiden, M Bortolozzi, F Di Leva, MH De Angelis, H Fuchs, D Lim, ... PLoS genetics 4 (10), e1000238, 2008 | 73 | 2008 |
The novel PMCA2 pump mutation Tommy impairs cytosolic calcium clearance in hair cells and links to deafness in mice M Bortolozzi, M Brini, N Parkinson, G Crispino, P Scimemi, RD De Siati, ... Journal of Biological Chemistry 285 (48), 37693-37703, 2010 | 71 | 2010 |
Heterogeneity of Ca2+ handling among and within Golgi compartments AKC Wong, P Capitanio, V Lissandron, M Bortolozzi, T Pozzan, P Pizzo Journal of molecular cell biology 5 (4), 266-276, 2013 | 60 | 2013 |
Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane A Burdyga, NC Surdo, S Monterisi, G Di Benedetto, F Grisan, E Penna, ... Proceedings of the National Academy of Sciences 115 (28), E6497-E6506, 2018 | 52 | 2018 |
Reduced phosphatidylinositol 4, 5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition L Rodriguez, E Simeonato, P Scimemi, F Anselmi, B Calì, G Crispino, ... Proceedings of the National Academy of Sciences 109 (35), 14013-14018, 2012 | 51 | 2012 |
What’s the function of connexin 32 in the peripheral nervous system? M Bortolozzi Frontiers in molecular neuroscience 11, 227, 2018 | 50 | 2018 |
Molecular dynamics simulations highlight structural and functional alterations in deafness–related M34T mutation of connexin 26 F Zonta, D Buratto, C Cassini, M Bortolozzi, F Mammano Frontiers in physiology 5, 85, 2014 | 45 | 2014 |
Impairment of human dopaminergic neurons at different developmental stages by perfluoro-octanoic acid (PFOA) and differential human brain areas accumulation of perfluoroalkyl … A Di Nisio, M Pannella, S Vogiatzis, S Sut, S Dall'Acqua, M Santa Rocca, ... Environment International 158, 106982, 2022 | 43 | 2022 |
Ca2+ signaling, apoptosis and autophagy in the developing cochlea: milestones to hearing acquisition F Mammano, M Bortolozzi Cell calcium 70, 117-126, 2018 | 43 | 2018 |