Exploiting the GTEx resources to decipher the mechanisms at GWAS loci AN Barbeira, R Bonazzola, ER Gamazon, Y Liang, YS Park, ... Genome biology 22, 1-24, 2021 | 217 | 2021 |
The long-term prognosis of cardiovascular disease and all-cause mortality for metabolically healthy obesity: a systematic review and meta-analysis R Zheng, D Zhou, Y Zhu J Epidemiol Community Health 70 (10), 1024-1031, 2016 | 193 | 2016 |
A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis D Zhou, Y Jiang, X Zhong, NJ Cox, C Liu, ER Gamazon Nature genetics 52 (11), 1239-1246, 2020 | 155 | 2020 |
Waist-to-Height Ratio: a simple, effective and practical screening tool for childhood obesity and metabolic syndrome D Zhou, M Yang, ZP Yuan, DD Zhang, L Liang, CL Wang, S Zhang, ... Preventive Medicine 67, 35-40, 2014 | 90 | 2014 |
Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi‐stage genome‐wide association study Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, ... Journal of cellular and molecular medicine 21 (6), 1106-1116, 2017 | 77 | 2017 |
Inferred divergent gene regulation in archaic hominins reveals potential phenotypic differences LL Colbran, ER Gamazon, D Zhou, P Evans, NJ Cox, JA Capra Nature ecology & evolution 3 (11), 1598-1606, 2019 | 50 | 2019 |
Alcohol consumption and smoking in relation to psoriasis: a Mendelian randomization study J Wei, J Zhu, H Xu, D Zhou, JT Elder, LC Tsoi, MT Patrick, Y Li British Journal of Dermatology 187 (5), 684-691, 2022 | 41 | 2022 |
A transcriptome-wide association study of Alzheimer’s disease using prediction models of relevant tissues identifies novel candidate susceptibility genes Y Sun, J Zhu, D Zhou, S Canchi, C Wu, NJ Cox, RA Rissman, ... Genome medicine 13, 1-11, 2021 | 37 | 2021 |
Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs D Zhou, Z Li, D Yu, L Wan, Y Zhu, M Lai, D Zhang Oncotarget 6 (37), 39995, 2015 | 34 | 2015 |
A transcriptome-wide association study identifies candidate susceptibility genes for pancreatic cancer risk D Liu, D Zhou, Y Sun, J Zhu, D Ghoneim, C Wu, Q Yao, ER Gamazon, ... Cancer research 80 (20), 4346-4354, 2020 | 33 | 2020 |
Cross-talks between gut microbiota and tobacco smoking: a two-sample Mendelian randomization study J Fan, Y Zhou, R Meng, J Tang, J Zhu, MC Aldrich, NJ Cox, Y Zhu, Y Li, ... BMC medicine 21 (1), 163, 2023 | 29 | 2023 |
Widespread dose-dependent effects of RNA expression and splicing on complex diseases and traits AN Barbeira, R Bonazzola, ER Gamazon, Y Liang, YS Park, ... BioRxiv, 814350, 2019 | 25 | 2019 |
Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: lessons from the Global Biobank Meta-analysis Initiative A Bhattacharya, JB Hirbo, D Zhou, W Zhou, J Zheng, M Kanai, B Pasaniuc, ... Cell genomics 2 (10), 2022 | 22 | 2022 |
Genetically increased circulating 25 (OH) D level reduces the risk of type 2 diabetes in subjects with deficiency of vitamin D: A large-scale Mendelian randomization study Y Xu, Y Zhou, J Liu, C Wang, Z Qu, Z Wei, D Zhou Medicine 99 (51), e23672, 2020 | 19 | 2020 |
Integration of genetic, transcriptomic, and clinical data provides insight into 16p11. 2 and 22q11. 2 CNV genes M Vysotskiy, X Zhong, TW Miller-Fleming, D Zhou, ... Genome Medicine 13, 1-26, 2021 | 18 | 2021 |
GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis F Han, L Zhang, C Chen, Y Wang, Y Zhang, L Qian, W Sun, D Zhou, ... Advanced Science 6 (23), 1901114, 2019 | 18 | 2019 |
Frailty and cardiometabolic diseases: a bidirectional Mendelian randomisation study J Zhu, D Zhou, J Wang, Y Yang, D Chen, F He, Y Li Age and ageing 51 (11), afac256, 2022 | 17 | 2022 |
A causal atlas on comorbidities in idiopathic pulmonary fibrosis: a bidirectional Mendelian randomization study J Zhu, D Zhou, J Wang, Y Yang, D Chen, F He, Y Li Chest 164 (2), 429-440, 2023 | 16 | 2023 |
A transcriptome‐wide association study identifies novel candidate susceptibility genes for prostate cancer risk D Liu, J Zhu, D Zhou, EG Nikas, NT Mitanis, Y Sun, C Wu, N Mancuso, ... International journal of cancer 150 (1), 80-90, 2022 | 15 | 2022 |
Contextualizing genetic risk score for disease screening and rare variant discovery D Zhou, D Yu, JM Scharf, CA Mathews, L McGrath, E Cook, SH Lee, ... Nature Communications 12 (1), 4418, 2021 | 15 | 2021 |