Crosstalk and interplay between the ubiquitin-proteasome system and autophagy CH Ji, YT Kwon Molecules and cells 40 (7), 441-449, 2017 | 298 | 2017 |
The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system CH Ji, HY Kim, MJ Lee, AJ Heo, DY Park, S Lim, S Shin, S Ganipisetti, ... Nature communications 13 (1), 904, 2022 | 147 | 2022 |
Role of cigarette smoke–induced aggresome formation in chronic obstructive pulmonary disease–emphysema pathogenesis I Tran, C Ji, I Ni, T Min, D Tang, N Vij American journal of respiratory cell and molecular biology 53 (2), 159-173, 2015 | 118 | 2015 |
The N-degron pathway mediates ER-phagy CH Ji, HY Kim, AJ Heo, SH Lee, MJ Lee, SB Kim, G Srinivasrao, SR Mun, ... Molecular cell 75 (5), 1058-1072. e9, 2019 | 110 | 2019 |
ZZ-dependent regulation of p62/SQSTM1 in autophagy Y Zhang, SR Mun, JF Linares, JW Ahn, CG Towers, CH Ji, BE Fitzwalter, ... Nature communications 9 (1), 4373, 2018 | 85 | 2018 |
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis YD Yoo, SR Mun, CH Ji, KW Sung, KY Kang, AJ Heo, SH Lee, JY An, ... Proceedings of the National Academy of Sciences 115 (12), E2716-E2724, 2018 | 73 | 2018 |
Second-hand cigarette smoke impairs bacterial phagocytosis in macrophages by modulating CFTR dependent lipid-rafts I Ni, C Ji, N Vij PloS one 10 (3), e0121200, 2015 | 58 | 2015 |
Glioma‐derived cancer stem cells are hypersensitive to proteasomal inhibition YD Yoo, DH Lee, H Cha‐Molstad, H Kim, SR Mun, C Ji, SH Park, ... EMBO reports 18 (1), 150-168, 2017 | 37 | 2017 |
The N-terminal cysteine is a dual sensor of oxygen and oxidative stress AJ Heo, SB Kim, CH Ji, D Han, SJ Lee, SH Lee, MJ Lee, JS Lee, ... Proceedings of the National Academy of Sciences 118 (50), e2107993118, 2021 | 34 | 2021 |
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy AJ Heo, CH Ji, YT Kwon Trends in Cell Biology 33 (3), 247-259, 2023 | 22 | 2023 |
p62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis SH Lee, WJ Cho, AJ Najy, AD Saliganan, T Pham, J Rakowski, ... Cell Death & Disease 12 (11), 997, 2021 | 19 | 2021 |
Regulation of reticulophagy by the N-degron pathway CH Ji, HY Kim, AJ Heo, MJ Lee, DY Park, DH Kim, BY Kim, YT Kwon Autophagy 16 (2), 373-375, 2020 | 17 | 2020 |
The function of FK506-binding protein 13 in protein quality control protects plasma cells from endoplasmic reticulum stress-associated apoptosis M Jeong, E Jang, SS Choi, C Ji, K Lee, J Youn Frontiers in Immunology 8, 222, 2017 | 16 | 2017 |
Targeted protein degradation via the autophagy-lysosome system: AUTOTAC (AUTOphagy-TArgeting Chimera) CH Ji, MJ Lee, HY Kim, AJ Heo, DY Park, YK Kim, BY Kim, YT Kwon Autophagy 18 (9), 2259-2262, 2022 | 14 | 2022 |
The N-degron pathway: From basic science to therapeutic applications AJ Heo, SB Kim, YT Kwon, CH Ji Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1866 (2), 194934, 2023 | 7 | 2023 |
Mitophagy and endoplasmic reticulum‐phagy accelerated by a p62 ZZ ligand alleviates paracetamol‐induced hepatotoxicity HY Kim, HS Yoon, AJ Heo, EJ Jung, CH Ji, SR Mun, MJ Lee, YT Kwon, ... British Journal of Pharmacology 180 (9), 1247-1266, 2023 | 5 | 2023 |
Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function X Lan, W Huang, SB Kim, D Fu, T Abeywansha, J Lou, U Balamurugan, ... Nature Communications 15 (1), 6350, 2024 | 1 | 2024 |
Mitophagy and ER-phagy accelerated by a p62 ZZ ligand alleviates acetaminophen-induced hepatotoxicity. HY Kim, HS Yoon, AJ Heo, EJ Jung, CH Ji, SR Mun, MJ Lee, YT Kwon, ... British Journal of Pharmacology, 2022 | 1 | 2022 |
P62 ligand compound and er-phagy-promoting use thereof YT Kwon, CH Ji, HY Kim, AJ Heo, S Ganipisetti US Patent App. 17/596,795, 2022 | 1 | 2022 |
Novel autotac chimeric compound, and composition for preventing, ameliorating or treating diseases through targeted protein degradation comprising the same YT Kwon, CH Ji, S Ganipisetti, HY Kim, SR Mun, CH Jung, EJ Jung, ... US Patent App. 17/262,157, 2021 | 1 | 2021 |