| Construction of homogeneous antibody–drug conjugates using site-selective protein chemistry P Akkapeddi, SA Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes Chemical Science 7 (5), 2954-2963, 2016 | 178 | 2016 |
| Chemoselective installation of amine bonds on proteins through aza-Michael ligation AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, ... Journal of the American Chemical Society 139 (50), 18365-18375, 2017 | 103 | 2017 |
| CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML ME Vinyard, C Su, AP Siegenfeld, AL Waterbury, AM Freedy, PM Gosavi, ... Nature chemical biology 15 (5), 529-539, 2019 | 97 | 2019 |
| Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile ZV Boskovic, MM Kemp, AM Freedy, VS Viswanathan, MS Pop, JH Fuller, ... ACS Chemical Biology 11 (7), 1844-1851, 2016 | 28 | 2016 |
| Discovering new biology with drug-resistance alleles AM Freedy, BB Liau Nature chemical biology 17 (12), 1219-1229, 2021 | 18 | 2021 |
| Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma HS Kwok, AM Freedy, AP Siegenfeld, JW Morriss, AL Waterbury, ... Nature chemical biology 19 (9), 1105-1115, 2023 | 7 | 2023 |
| Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma HS Kwok, AM Freedy, AP Siegenfeld, JW Morriss, AL Waterbury, ... bioRxiv, 2022.04. 04.486977, 2022 | 3 | 2022 |
| An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing AL Waterbury, HS Kwok, C Lee, DN Narducci, AM Freedy, C Su, S Raval, ... Molecular Cell, 2024 | 1 | 2024 |
| Differentiation of Acute Myeloid Leukemia Cells upon Pharmacological Inhibition of LSD1 Requires Its N-Terminal Intrinsically Disordered Region HS Kwok, A Waterbury, C Lee, D Narducci, A Freedy, C Su, A Reiter, ... Blood 142, 1416, 2023 | | 2023 |
| Drug addiction mutations unveil a repressive methylation ceiling in EZH2-mutant lymphoma HS Kwok, A Freedy, A Siegenfeld, J Morriss, A Waterbury, S Kissler, ... | | 2022 |
| Uncovering the biology of chromatin regulators with drug resistance alleles AM Freedy Harvard University, 2022 | | 2022 |
Gonçalo BernardesYusuf Hamied Department Chemistry, University of Cambridge在 cam.ac.uk 的电子邮件经过验证
