The many faces of α-synuclein: from structure and toxicity to therapeutic target HA Lashuel, CR Overk, A Oueslati, E Masliah Nature Reviews Neuroscience 14 (1), 38-48, 2013 | 1750 | 2013 |
Role of post-translational modifications in modulating the structure, function and toxicity of α-synuclein: implications for Parkinson’s disease pathogenesis and therapies A Oueslati, M Fournier, HA Lashuel Progress in brain research 183, 115-145, 2010 | 447 | 2010 |
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization, and influences synuclein-membrane interactions KE Paleologou, A Oueslati, G Shakked, CC Rospigliosi, HY Kim, ... Journal of Neuroscience 30 (9), 3184-3198, 2010 | 402 | 2010 |
Implication of alpha-synuclein phosphorylation at S129 in synucleinopathies: what have we learned in the last decade? A Oueslati Journal of Parkinson's disease 6 (1), 39-51, 2016 | 341 | 2016 |
Phosphorylation of synucleins by members of the Polo-like kinase family MK Mbefo, KE Paleologou, A Boucharaba, A Oueslati, H Schell, ... Journal of Biological Chemistry 285 (4), 2807-2822, 2010 | 289 | 2010 |
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease AL Mahul-Mellier, B Fauvet, A Gysbers, I Dikiy, A Oueslati, S Georgeon, ... Human molecular genetics 23 (11), 2858-2879, 2014 | 243 | 2014 |
Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo A Oueslati, BL Schneider, P Aebischer, HA Lashuel Proceedings of the National Academy of Sciences 110 (41), E3945-E3954, 2013 | 226 | 2013 |
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity O Khalaf, B Fauvet, A Oueslati, I Dikiy, AL Mahul-Mellier, FS Ruggeri, ... Journal of Biological Chemistry 289 (32), 21856-21876, 2014 | 219 | 2014 |
Human-to-mouse prion-like propagation of mutant huntingtin protein I Jeon, F Cicchetti, G Cisbani, S Lee, E Li, J Bae, N Lee, L Li, W Im, M Kim, ... Acta neuropathologica 132, 577-592, 2016 | 187 | 2016 |
Mimicking phosphorylation at serine 87 inhibits the aggregation of human α-synuclein and protects against its toxicity in a rat model of Parkinson's disease A Oueslati, KE Paleologou, BL Schneider, P Aebischer, HA Lashuel Journal of Neuroscience 32 (5), 1536-1544, 2012 | 119 | 2012 |
Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease MB Fares, B Maco, A Oueslati, E Rockenstein, N Ninkina, VL Buchman, ... Proceedings of the National Academy of Sciences 113 (7), E912-E921, 2016 | 118 | 2016 |
Chronic high‐frequency stimulation of the subthalamic nucleus and L‐DOPA treatment in experimental parkinsonism: effects on motor behaviour and striatal glutamate transmission P Gubellini, A Eusebio, A Oueslati, C Melon, L Kerkerian‐Le Goff, P Salin European Journal of Neuroscience 24 (6), 1802-1814, 2006 | 90 | 2006 |
Photobiomodulation suppresses alpha-synuclein-induced toxicity in an AAV-based rat genetic model of Parkinson’s disease A Oueslati, B Lovisa, J Perrin, G Wagnières, H van den Bergh, Y Tardy, ... PloS one 10 (10), e0140880, 2015 | 81 | 2015 |
High-frequency stimulation of the subthalamic nucleus potentiates L-DOPA-induced neurochemical changes in the striatum in a rat model of Parkinson's disease A Oueslati, V Sgambato-Faure, C Melon, P Kachidian, P Gubellini, M Amri, ... Journal of Neuroscience 27 (9), 2377-2386, 2007 | 81 | 2007 |
Protein transmission, seeding and degradation: key steps for α-synuclein prion-like propagation A Oueslati, M Ximerakis, K Vekrellis Experimental neurobiology 23 (4), 324, 2014 | 70 | 2014 |
Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo MK Mbefo, MB Fares, K Paleologou, A Oueslati, G Yin, S Tenreiro, ... Journal of Biological Chemistry 290 (15), 9412-9427, 2015 | 65 | 2015 |
Dysfunction of the cortico‐basal ganglia‐cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism A Oueslati, N Breysse, M Amalric, L Kerkerian‐Le Goff, P Salin European Journal of Neuroscience 22 (11), 2765-2774, 2005 | 48 | 2005 |
Dissecting the molecular pathway involved in PLK2 kinase-mediated α-synuclein-selective autophagic degradation M Dahmene, M Bérard, A Oueslati Journal of Biological Chemistry 292 (9), 3919-3928, 2017 | 36 | 2017 |
Shedding a new light on Huntington’s disease: How blood can both propagate and ameliorate disease pathology M Rieux, M Alpaugh, G Sciacca, M Saint-Pierre, M Masnata, HL Denis, ... Molecular psychiatry 26 (9), 5441-5463, 2021 | 31 | 2021 |
Alpha-Synuclein and the endolysosomal system in parkinson’s disease: guilty by association M Teixeira, R Sheta, W Idi, A Oueslati Biomolecules 11 (9), 1333, 2021 | 29 | 2021 |