Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands DB Tikhonov, BS Zhorov Biophysical journal 88 (1), 184-197, 2005 | 151 | 2005 |
Potassium, sodium, calcium and glutamate‐gated channels: pore architecture and ligand action BS Zhorov, DB Tikhonov Journal of neurochemistry 88 (4), 782-799, 2004 | 145 | 2004 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants DB Tikhonov, BS Zhorov The Journal of general physiology 149 (4), 465-481, 2017 | 133 | 2017 |
Determinants of trapping block of N‐methyl‐d‐aspartate receptor channels KV Bolshakov, VE Gmiro, DB Tikhonov, LG Magazanik Journal of neurochemistry 87 (1), 56-65, 2003 | 124 | 2003 |
Structural model for dihydropyridine binding to L-type calcium channels DB Tikhonov, BS Zhorov Journal of Biological Chemistry 284 (28), 19006-19017, 2009 | 114 | 2009 |
Architecture and pore block of eukaryotic voltage-gated sodium channels in view of NavAb bacterial sodium channel structure DB Tikhonov, BS Zhorov Molecular pharmacology 82 (1), 97-104, 2012 | 113 | 2012 |
Influence of external magnesium ions on the NMDA receptor channel block by different types of organic cations MV Nikolaev, LG Magazanik, DB Tikhonov Neuropharmacology 62 (5-6), 2078-2085, 2012 | 91 | 2012 |
Design of antagonists for NMDA and AMPA receptors KV Bolshakov, KH Kim, NN Potapjeva, VE Gmiro, DB Tikhonov, ... Neuropharmacology 49 (2), 144-155, 2005 | 85 | 2005 |
How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis SY Wang, J Mitchell, DB Tikhonov, BS Zhorov, GK Wang Molecular pharmacology 69 (3), 788-795, 2006 | 83 | 2006 |
Access and binding of local anesthetics in the closed sodium channel I Bruhova, DB Tikhonov, BS Zhorov Molecular pharmacology 74 (4), 1033-1045, 2008 | 80 | 2008 |
Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics OI Barygin, EI Nagaeva, DB Tikhonov, DA Belinskaya, NP Vanchakova, ... Brain research 1660, 58-66, 2017 | 78 | 2017 |
Sodium channel activators: model of binding inside the pore and a possible mechanism of action DB Tikhonov, BS Zhorov FEBS letters 579 (20), 4207-4212, 2005 | 78 | 2005 |
Sodium channels: ionic model of slow inactivation and state-dependent drug binding DB Tikhonov, BS Zhorov Biophysical journal 93 (5), 1557-1570, 2007 | 70 | 2007 |
Characterization of acid-sensitive ion channels in freshly isolated rat brain neurons KV Bolshakov, KV Essin, SL Buldakova, NA Dorofeeva, SN Skatchkov, ... Neuroscience 110 (4), 723-730, 2002 | 67 | 2002 |
Modeling of the pore domain of the GLUR1 channel: homology with K+ channel and binding of channel blockers DB Tikhonov, JR Mellor, PNR Usherwood, LG Magazanik Biophysical journal 82 (4), 1884-1893, 2002 | 67 | 2002 |
Structural model for phenylalkylamine binding to L-type calcium channels RCK Cheng, DB Tikhonov, BS Zhorov Journal of Biological Chemistry 284 (41), 28332-28342, 2009 | 65 | 2009 |
Voltage‐dependent block of native AMPA receptor channels by dicationic compounds DB Tikhonov, MV Samoilova, SL Buldakova, VE Gmiro, LG Magazanik British journal of pharmacology 129 (2), 265-274, 2000 | 65 | 2000 |
Different arrangement of hydrophobic and nucleophilic components of channel binding sites in N-methyl-D-aspartate and AMPA receptors of rat brain is revealed by channel blockade KV Bolshakov, DB Tikhonov, VE Gmiro, LG Magazanik Neuroscience letters 291 (2), 101-104, 2000 | 64 | 2000 |
Origin and molecular evolution of ionotropic glutamate receptors DB Tikhonov, LG Magazanik Neuroscience and behavioral physiology 39 (8), 763-773, 2009 | 59 | 2009 |
Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues K Strømgaard, TJ Brier, K Andersen, IR Mellor, A Saghyan, D Tikhonov, ... Journal of medicinal chemistry 43 (23), 4526-4533, 2000 | 58 | 2000 |