Characterization of the inflammatory response to severe COVID-19 illness OJ McElvaney, NL McEvoy, OF McElvaney, TP Carroll, MP Murphy, ... American journal of respiratory and critical care medicine 202 (6), 812-821, 2020 | 667 | 2020 |
Erlotinib or gefitinib for the treatment of relapsed platinum pretreated non-small cell lung cancer and ovarian cancer: a systematic review M Murphy, B Stordal Drug Resistance Updates 14 (3), 177-190, 2011 | 78 | 2011 |
The in vitro host cell immune response to bovine-adapted Staphylococcus aureus varies according to bacterial lineage MP Murphy, DA Niedziela, FC Leonard, OM Keane Scientific reports 9 (1), 6134, 2019 | 37 | 2019 |
Mcl-1 is vital for neutrophil survival MP Murphy, E Caraher Immunologic research 62, 225-233, 2015 | 34 | 2015 |
Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency ME O'Brien, L Fee, N Browne, TP Carroll, P Meleady, M Henry, ... Thorax 75 (4), 321-330, 2020 | 31 | 2020 |
Residence in biofilms allows Burkholderia cepacia complex (Bcc) bacteria to evade the antimicrobial activities of neutrophil-like dHL60 cells MP Murphy, E Caraher Pathogens and disease 73 (8), ftv069, 2015 | 30 | 2015 |
Effect of elexacaftor/tezacaftor/ivacaftor on airway and systemic inflammation in cystic fibrosis M Casey, C Gabillard-Lefort, OF McElvaney, OJ McElvaney, T Carroll, ... Thorax 78 (8), 835-839, 2023 | 27 | 2023 |
A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19 OJ McElvaney, NL McEvoy, F Boland, OF McElvaney, G Hogan, ... Med 3 (4), 233-248. e6, 2022 | 23 | 2022 |
Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications OF McElvaney, T Asakura, SL Meinig, JL Torres-Castillo, RS Hagan, ... EBioMedicine 77, 2022 | 21 | 2022 |
Clinical presentation and immune characteristics in first-lactation Holstein-Friesian cows following intramammary infection with genotypically distinct Staphylococcus aureus … DA Niedziela, MP Murphy, J Grant, OM Keane, FC Leonard Journal of dairy science 103 (9), 8453-8466, 2020 | 21 | 2020 |
α1 Antitrypsin therapy modulates the neutrophil membrane proteome and secretome MP Murphy, T McEnery, K McQuillan, OF McElvaney, OJ McElvaney, ... European Respiratory Journal 55 (4), 2020 | 21 | 2020 |
Altered degranulation and pH of neutrophil phagosomes impacts antimicrobial efficiency in cystic fibrosis E Hayes, MP Murphy, K Pohl, N Browne, K McQuillan, LE Saw, C Foley, ... Frontiers in Immunology 11, 600033, 2020 | 20 | 2020 |
Targeting airway inflammation in cystic fibrosis OJ McElvaney, P Wade, M Murphy, EP Reeves, NG McElvaney Expert review of respiratory medicine 13 (11), 1041-1055, 2019 | 19 | 2019 |
Augmentation therapy for severe alpha-1 antitrypsin deficiency improves survival and is decoupled from spirometric decline—a multinational registry analysis DD Fraughen, AJ Ghosh, BD Hobbs, GC Funk, T Meischl, CF Clarenbach, ... American Journal of Respiratory and Critical Care Medicine 208 (9), 964-974, 2023 | 10 | 2023 |
Targeting IgG autoantibodies for improved cytotoxicity of bactericidal permeability increasing protein in cystic fibrosis K McQuillan, F Gargoum, MP Murphy, OJ McElvaney, NG McElvaney, ... Frontiers in Pharmacology 11, 1098, 2020 | 10 | 2020 |
Current and emerging therapies for the treatment of cystic fibrosis or mitigation of its symptoms MP Murphy, E Caraher Drugs in R&D 16, 1-17, 2016 | 10 | 2016 |
Anti-cytokines as a strategy in alpha-1 antitrypsin deficiency OF McElvaney, MP Murphy, EP Reeves, NG McElvaney Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation 7 (3 …, 2020 | 9 | 2020 |
Attitudes towards vaccination for coronavirus disease 2019 in patients with severe alpha-1 antitrypsin deficiency OJ McElvaney, B Cleary, DD Fraughen, G Kelly, MP Murphy, ... Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation 9 (2 …, 2022 | 4 | 2022 |
C3d elicits neutrophil degranulation and decreases endothelial cell migration, with implications for patients with alpha-1 antitrypsin deficiency LT Fee, D Gogoi, ME O’Brien, E McHugh, M Casey, C Gough, M Murphy, ... Biomedicines 9 (12), 1925, 2021 | 4 | 2021 |
EHS matrix incubated in media containing penicillin retains sufficient concentrations of antibiotic to inhibit growth of susceptible microorganisms MP Murphy, DA Niedziela, OM Keane Journal of microbiological methods 139, 103-106, 2017 | 4 | 2017 |