| DNA repair targeted therapy: The past or future of cancer treatment? NS Gavande, PS VanderVere-Carozza, HD Hinshaw, SI Jalal, CR Sears, ... Pharmacology & therapeutics 160, 65-83, 2016 | 409 | 2016 |
| Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology SC Shuck, EA Short, JJ Turchi Cell research 18 (1), 64-72, 2008 | 364 | 2008 |
| Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53 LD Mayo, JJ Turchi, SJ Berberich Cancer research 57 (22), 5013-5016, 1997 | 339 | 1997 |
| Chemotherapy induced DNA damage response: convergence of drugs and pathways D Woods, JJ Turchi Cancer biology & therapy 14 (5), 379-389, 2013 | 322 | 2013 |
| Cisplatin-induced apoptosis proceeds by caspase-3-dependent and-independent pathways in cisplatin-resistant and-sensitive human ovarian cancer cell lines KM Henkels, JJ Turchi Cancer research 59 (13), 3077-3083, 1999 | 319 | 1999 |
| Enzymatic completion of mammalian lagging-strand DNA replication. JJ TuRCHI, L Huang, RS Murante, Y Kim, RA Bambara Proceedings of the National Academy of Sciences 91 (21), 9803-9807, 1994 | 257 | 1994 |
| Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency K Cong, M Peng, AN Kousholt, WTC Lee, S Lee, S Nayak, J Krais, ... Molecular cell 81 (15), 3128-3144. e7, 2021 | 241 | 2021 |
| Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2 K Lillard-Wetherell, A Machwe, GT Langland, KA Combs, GK Behbehani, ... Human molecular genetics 13 (17), 1919-1932, 2004 | 203 | 2004 |
| Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of nonhomologous end joining HJ Boeckman, KS Trego, JJ Turchi Molecular cancer research 3 (5), 277-285, 2005 | 190 | 2005 |
| Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks L Zheng, M Zhou, Q Chai, J Parrish, D Xue, SM Patrick, JJ Turchi, ... EMBO reports 6 (1), 83-89, 2005 | 186 | 2005 |
| Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum− DNA adducts A Vaisman, SE Lim, SM Patrick, WC Copeland, DC Hinkle, JJ Turchi, ... Biochemistry 38 (34), 11026-11039, 1999 | 178 | 1999 |
| The calf 5 ‘-to 3 ‘-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage. RS Murante, L Huang, JJ Turchi, RA Bambara Journal of Biological Chemistry 269 (2), 1191-1196, 1994 | 166 | 1994 |
| RPA phosphorylation in mitosis alters DNA binding and protein− protein interactions GG Oakley, SM Patrick, J Yao, MP Carty, JJ Turchi, K Dixon Biochemistry 42 (11), 3255-3264, 2003 | 153 | 2003 |
| DNA repair: from genome maintenance to biomarker and therapeutic target S Jalal, JN Earley, JJ Turchi Clinical cancer research 17 (22), 6973-6984, 2011 | 141 | 2011 |
| Induction of apoptosis in cisplatin-sensitive and-resistant human ovarian cancer cell lines KM Henkels, JJ Turchi Cancer research 57 (20), 4488-4492, 1997 | 141 | 1997 |
| Modulating DNA repair pathways to improve precision genome engineering KS Pawelczak, NS Gavande, PS VanderVere-Carozza, JJ Turchi ACS chemical biology 13 (2), 389-396, 2018 | 140 | 2018 |
| Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A C Ramilo, L Gu, S Guo, X Zhang, SM Patrick, JJ Turchi, GM Li Molecular and cellular biology, 2002 | 133 | 2002 |
| The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer F Fang, J Munck, J Tang, P Taverna, Y Wang, DFB Miller, J Pilrose, ... Clinical cancer research 20 (24), 6504-6516, 2014 | 128 | 2014 |
| Replication protein A (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA SM Patrick, JJ Turchi Journal of Biological Chemistry 274 (21), 14972-14978, 1999 | 127 | 1999 |
| Behavior of T7 RNA polymerase and mammalian RNA polymerase II at site-specific cisplatin adducts in the template DNA S Tornaletti, SM Patrick, JJ Turchi, PC Hanawalt Journal of Biological Chemistry 278 (37), 35791-35797, 2003 | 124 | 2003 |
Navnath GavandeAssistant Professor Wayne State University College of Pharmacy, Detroit, Michigan, USA在 wayne.edu 的电子邮件经过验证
