Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility HD Williams, Y Sahbaz, L Ford, TH Nguyen, PJ Scammells, CJH Porter Chemical communications 50 (14), 1688-1690, 2014 | 151 | 2014 |
Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations Y Sahbaz, HD Williams, TH Nguyen, J Saunders, L Ford, SA Charman, ... Molecular pharmaceutics 12 (6), 1980-1991, 2015 | 142 | 2015 |
Further studies on the biodegradation of ionic liquids L Ford, JR Harjani, F Atefi, MT Garcia, RD Singer, PJ Scammells Green chemistry 12 (10), 1783-1789, 2010 | 65 | 2010 |
Ionic liquid forms of weakly acidic drugs in oral lipid formulations: preparation, characterization, in vitro digestion, and in vivo absorption studies Y Sahbaz, TH Nguyen, L Ford, CL McEvoy, HD Williams, PJ Scammells, ... Molecular Pharmaceutics 14 (11), 3669-3683, 2017 | 59 | 2017 |
Cyclosporin structure and permeability: from A to Z and beyond KM Corbett, L Ford, DB Warren, CW Pouton, DK Chalmers Journal of Medicinal Chemistry 64 (18), 13131-13151, 2021 | 55 | 2021 |
Transformation of biopharmaceutical classification system class I and III drugs into ionic liquids and lipophilic salts for enhanced developability using lipid formulations HD Williams, L Ford, S Lim, S Han, J Baumann, H Sullivan, D Vodak, ... Journal of pharmaceutical sciences 107 (1), 203-216, 2018 | 50 | 2018 |
Role of catechol in the radical reduction of B-alkylcatecholboranes in presence of methanol G Povie, G Villa, L Ford, D Pozzi, CH Schiesser, P Renaud Chemical communications 46 (5), 803-805, 2010 | 50 | 2010 |
Radicals and transition-metal catalysis: an alliance par excellence to increase reactivity and selectivity in organic chemistry L Ford, U Jahn Angewandte Chemie-International Edition 48 (35), 6386-6389, 2009 | 49 | 2009 |
Unlocking the full potential of lipid-based formulations using lipophilic salt/ionic liquid forms HD Williams, L Ford, A Igonin, Z Shan, P Botti, MM Morgen, G Hu, ... Advanced drug delivery reviews 142, 75-90, 2019 | 45 | 2019 |
Enhancing the oral absorption of kinase inhibitors using lipophilic salts and lipid-based formulations HD Williams, L Ford, S Han, KJ Tangso, S Lim, DM Shackleford, ... Molecular Pharmaceutics 15 (12), 5678-5696, 2018 | 40 | 2018 |
The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling EA Vecchio, CH Chuo, JA Baltos, L Ford, PJ Scammells, BH Wang, ... Biochemical pharmacology 117, 46-56, 2016 | 39 | 2016 |
Grignard reactions in pyridinium and phosphonium ionic liquids L Ford, F Atefi, RD Singer, PJ Scammells European Journal of Organic Chemistry 2011 (5), 942-950, 2011 | 34 | 2011 |
Ionic liquid forms of the antimalarial lumefantrine in combination with LFCS type IIIB lipid-based formulations preferentially increase lipid solubility, in vitro … E Tay, TH Nguyen, L Ford, HD Williams, H Benameur, PJ Scammells, ... Pharmaceutics 12 (1), 17, 2019 | 30 | 2019 |
Catechols as sources of hydrogen atoms in radical deiodination and related reactions G Povie, L Ford, D Pozzi, V Soulard, G Villa, P Renaud Angewandte Chemie International Edition 55 (37), 11221-11225, 2016 | 30 | 2016 |
A Structure–Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists L Aurelio, JA Baltos, L Ford, ATN Nguyen, M Jorg, SM Devine, C Valant, ... Journal of medicinal chemistry 61 (5), 2087-2103, 2018 | 28 | 2018 |
Discovery and in vivo evaluation of alcohol-containing benzothiazoles as potent dual-targeting bacterial DNA supercoiling inhibitors JT Palmer, LC Axford, S Barker, JM Bennett, M Blair, I Collins, DT Davies, ... Bioorganic & Medicinal Chemistry Letters 24 (17), 4215-4222, 2014 | 21 | 2014 |
Highly Functionalized and Potent Antiviral Cyclopentane Derivatives Formed by a Tandem Process Consisting of Organometallic, Transition‐Metal‐Catalyzed, and Radical Reaction Steps PR Jagtap, L Ford, E Deister, R Pohl, I Císařová, J Hodek, J Weber, ... Chemistry–A European Journal 20 (33), 10298-10304, 2014 | 20 | 2014 |
API ionic liquids: probing the effect of counterion structure on physical form and lipid solubility L Ford, E Tay, TH Nguyen, HD Williams, H Benameur, PJ Scammells, ... RSC advances 10 (22), 12788-12799, 2020 | 17 | 2020 |
Radikale und Übergangsmetallkatalyse–eine Allianz par excellence zur Steigerung von Reaktivität und Selektivität in der organischen Chemie L Ford, U Jahn Angewandte Chemie 121 (35), 6504-6507, 2009 | 15 | 2009 |
Nitrogen-containing ionic liquids: biodegradation studies and utility in base-mediated reactions L Ford, KEO Ylijoki, MT Garcia, RD Singer, PJ Scammells Australian Journal of Chemistry 68 (6), 849-857, 2014 | 11 | 2014 |