Efficient differentiation of human pluripotent stem cells to endothelial progenitors via small-molecule activation of WNT signaling X Lian, X Bao, A Al-Ahmad, J Liu, Y Wu, W Dong, KK Dunn, EV Shusta, ... Stem cell reports 3 (5), 804-816, 2014 | 353 | 2014 |
Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis W Dong, MA Keibler, G Stephanopoulos Metabolic engineering 43, 113-124, 2017 | 70 | 2017 |
Ferroptosis regulation by the NGLY1/NFE2L1 pathway GC Forcina, L Pope, M Murray, W Dong, M Abu-Remaileh, CR Bertozzi, ... Proceedings of the National Academy of Sciences 119 (11), e2118646119, 2022 | 64 | 2022 |
Oxidative pentose phosphate pathway and glucose anaplerosis support maintenance of mitochondrial NADPH pool under mitochondrial oxidative stress SJ Moon, W Dong, GN Stephanopoulos, HD Sikes Bioengineering & translational medicine 5 (3), e10184, 2020 | 61 | 2020 |
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes NN Laqtom, W Dong, UN Medoh, AL Cangelosi, V Dharamdasani, ... Nature 609 (7929), 1005-1011, 2022 | 58 | 2022 |
Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth CH Man, FE Mercier, N Liu, W Dong, G Stephanopoulos, L Jiang, Y Jung, ... Blood, The Journal of the American Society of Hematology 139 (4), 502-522, 2022 | 32 | 2022 |
Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein DA Armenta, NN Laqtom, G Alchemy, W Dong, D Morrow, CD Poltorack, ... Cell chemical biology 29 (11), 1588-1600. e7, 2022 | 31 | 2022 |
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia MS Haney, R Pálovics, CN Munson, C Long, PK Johansson, O Yip, ... Nature 628 (8006), 154-161, 2024 | 30 | 2024 |
Isotope tracing in health and disease W Dong, ES Rawat, G Stephanopoulos, M Abu-Remaileh Current opinion in biotechnology 76, 102739, 2022 | 20 | 2022 |
The Batten disease gene product CLN5 is the lysosomal bis (monoacylglycero) phosphate synthase UN Medoh, A Hims, JY Chen, A Ghoochani, K Nyame, W Dong, ... Science 381 (6663), 1182-1189, 2023 | 18 | 2023 |
Golgi-IP, a tool for multimodal analysis of Golgi molecular content R Fasimoye‡, W Dong‡, RS Nirujogi‡, ES Rawat, M Iguchi, K Nyame, ... Proceedings of the National Academy of Sciences 120 (20), e2219953120, 2023 | 18 | 2023 |
An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation SG Scharenberg‡, W Dong‡, A Ghoochani, K Nyame, ... Science Advances 9 (16), eadf8966, 2023 | 18 | 2023 |
Glyceraldehyde 3‐phosphate dehydrogenase modulates nonoxidative pentose phosphate pathway to provide anabolic precursors in hypoxic tumor cells WS Ahn, W Dong, Z Zhang, JR Cantor, DM Sabatini, O Iliopoulos, ... AIChE Journal 64 (12), 4289-4296, 2018 | 15 | 2018 |
Dissecting Mammalian Cell Metabolism through 13C- and 2H-Isotope Tracing: Interpretations at the Molecular and Systems Levels W Dong, SJ Moon, JK Kelleher, G Stephanopoulos Industrial & Engineering Chemistry Research 59 (6), 2593-2610, 2019 | 14 | 2019 |
Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes MS Isidor, W Dong, RI Servin-Uribe, J Villarroel, A Altıntaş, ... International Journal of Obesity 46 (3), 535-543, 2022 | 10 | 2022 |
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells J Hsu, N Fatuzzo, N Weng, W Michno, W Dong, M Kienle, Y Dai, A Pasca, ... Journal of Biological Chemistry 299 (2), 2023 | 9 | 2023 |
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia MS Haney, R Palovics, CN Munson, C Long, P Johansson, O Yip, ... bioRxiv, 2023 | 8 | 2023 |
Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells W Dong, MA Keibler, SJ Moon, P Cho, N Liu, CJ Berrios, JK Kelleher, ... bioRxiv, 2022.04. 08.486845, 2022 | 8 | 2022 |
Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein. Cell Chem. Biol. 29, 1588–1600. e7 DA Armenta, NN Laqtom, G Alchemy, W Dong, D Morrow, CD Poltorack, ... | 5 | 2022 |
Differential substrate use in EGF‐and oncogenic KRAS‐stimulated human mammary epithelial cells MA Keibler, W Dong, KD Korthauer, AM Hosios, SJ Moon, LB Sullivan, ... The FEBS journal 288 (19), 5629-5649, 2021 | 5 | 2021 |