| Comparison of PAM50 Risk of Recurrence Score With Oncotype DX and IHC4 for Predicting Risk of Distant Recurrence After Endocrine Therapy M Dowsett, I Sestak, E Lopez-Knowles, K Sidhu, AK Dunbier, JW Cowens, ... Journal of Clinical Oncology 31 (22), 2783-2790, 2013 | 740 | 2013 |
| Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer G Schiavon, S Hrebien, I Garcia-Murillas, RJ Cutts, A Pearson, ... Science translational medicine 7 (313), 313ra182-313ra182, 2015 | 579 | 2015 |
| Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene … DC Sgroi, I Sestak, J Cuzick, Y Zhang, CA Schnabel, B Schroeder, ... The lancet oncology 14 (11), 1067-1076, 2013 | 437 | 2013 |
| PI3K pathway activation in breast cancer is associated with the basal‐like phenotype and cancer‐specific mortality E López‐Knowles, SA O'Toole, CM McNeil, EKA Millar, MR Qiu, P Crea, ... International journal of cancer 126 (5), 1121-1131, 2010 | 401 | 2010 |
| Prospective Study of FGFR3 Mutations As a Prognostic Factor in Nonmuscle Invasive Urothelial Bladder Carcinomas S Hernández, E López-Knowles, J Lloreta, M Kogevinas, A Amorós, ... Journal of Clinical Oncology 24 (22), 3664-3671, 2006 | 398 | 2006 |
| Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers CG Fedele, LM Ooms, M Ho, J Vieusseux, SA O'Toole, EK Millar, ... Proceedings of the National Academy of Sciences 107 (51), 22231-22236, 2010 | 327 | 2010 |
| Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy C Balbás-Martínez, A Sagrera, E Carrillo-de-Santa-Pau, J Earl, ... Nature genetics 45 (12), 1464-1469, 2013 | 323 | 2013 |
| PIK3CA Mutations Are an Early Genetic Alteration Associated with FGFR3 Mutations in Superficial Papillary Bladder Tumors E López-Knowles, S Hernández, N Malats, M Kogevinas, J Lloreta, ... Cancer research 66 (15), 7401-7404, 2006 | 286 | 2006 |
| Prediction of late distant recurrence after 5 years of endocrine treatment: a combined analysis of patients from the Austrian breast and colorectal cancer study group 8 and … I Sestak, J Cuzick, M Dowsett, E Lopez-Knowles, M Filipits, P Dubsky, ... Journal of clinical oncology 33 (8), 916-922, 2015 | 267 | 2015 |
| Factors predicting late recurrence for estrogen receptor–positive breast cancer I Sestak, M Dowsett, L Zabaglo, E Lopez-Knowles, S Ferree, JW Cowens, ... Journal of the National Cancer Institute 105 (19), 1504-1511, 2013 | 250 | 2013 |
| Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern C Hafner, E López-Knowles, NM Luis, A Toll, E Baselga, ... Proceedings of the National Academy of Sciences 104 (33), 13450-13454, 2007 | 247 | 2007 |
| Cytoplasmic localization of β-catenin is a marker of poor outcome in breast cancer patients E López-Knowles, SJ Zardawi, CM McNeil, EKA Millar, P Crea, ... Cancer epidemiology, biomarkers & prevention 19 (1), 301-309, 2010 | 217 | 2010 |
| FGFR3 and Tp53 Mutations in T1G3 Transitional Bladder Carcinomas: Independent Distribution and Lack of Association with Prognosis S Hernández, E López-Knowles, J Lloreta, M Kogevinas, R Jaramillo, ... Clinical Cancer Research 11 (15), 5444-5450, 2005 | 156 | 2005 |
| Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ... Nature genetics 48 (4), 374-386, 2016 | 155 | 2016 |
| Identifying clinically relevant prognostic subgroups of postmenopausal women with node-positive hormone receptor-positive early-stage breast cancer treated with endocrine … M Gnant, I Sestak, M Filipits, M Dowsett, M Balic, E Lopez-Knowles, ... Annals of Oncology 26 (8), 1685-1691, 2015 | 138 | 2015 |
| Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data D Zardavas, L Te Marvelde, RL Milne, D Fumagalli, G Fountzilas, ... Journal of Clinical Oncology 36 (10), 981-990, 2018 | 114 | 2018 |
| Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment SC Drury, S Detre, A Leary, J Salter, J Reis-Filho, V Barbashina, ... Endocrine Related Cancer 18 (5), 565, 2011 | 107 | 2011 |
| Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance A Pearson, P Proszek, J Pascual, C Fribbens, MK Shamsher, B Kingston, ... Clinical Cancer Research 26 (3), 608-622, 2020 | 104 | 2020 |
| High Notch1 protein expression is an early event in breast cancer development and is associated with the HER‐2 molecular subtype SJ Zardawi, I Zardawi, CM McNeil, EKA Millar, D McLeod, AL Morey, ... Histopathology 56 (3), 286-296, 2010 | 86 | 2010 |
| β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression B Schade, R Lesurf, V Sanguin-Gendreau, T Bui, G Deblois, SA O'Toole, ... Cancer research 73 (14), 4474-4487, 2013 | 85 | 2013 |
