Novel designer receptors to probe GPCR signaling and physiology J Wess, K Nakajima, S Jain Trends in pharmacological sciences 34 (7), 385-392, 2013 | 190 | 2013 |
Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds K Masuda, A Koizumi, K Nakajima, T Tanaka, K Abe, T Misaka, M Ishiguro PloS one 7 (4), e35380, 2012 | 182 | 2012 |
Design and functional characterization of a novel, arrestin-biased designer G protein-coupled receptor K Nakajima, J Wess Molecular pharmacology 82 (4), 575-582, 2012 | 143 | 2012 |
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake K Nakajima, Z Cui, C Li, J Meister, Y Cui, O Fu, AS Smith, S Jain, ... Nature communications 7 (1), 10268, 2016 | 114 | 2016 |
Human sweet taste receptor mediates acid-induced sweetness of miraculin A Koizumi, A Tsuchiya, K Nakajima, K Ito, T Terada, A Shimizu-Ibuka, ... Proceedings of the National Academy of Sciences 108 (40), 16819-16824, 2011 | 94 | 2011 |
Taste-modifying sweet protein, neoculin, is received at human T1R3 amino terminal domain A Koizumi, K Nakajima, T Asakura, Y Morita, K Ito, A Shmizu-Ibuka, ... Biochemical and biophysical research communications 358 (2), 585-589, 2007 | 88 | 2007 |
Neoculin as a new taste-modifying protein occurring in the fruit of Curculigo latifolia Y Shirasuka, K Nakajima, T Asakura, H Yamashita, A Yamamoto, S Hata, ... Bioscience, biotechnology, and biochemistry 68 (6), 1403-1407, 2004 | 85 | 2004 |
Microbial production of sensory-active miraculin K Ito, T Asakura, Y Morita, K Nakajima, A Koizumi, A Shimizu-Ibuka, ... Biochemical and biophysical research communications 360 (2), 407-411, 2007 | 84 | 2007 |
Extracellular Production of Neoculin, a Sweet-Tasting Heterodimeric Protein with Taste-Modifying Activity, by Aspergillus oryzae K Nakajima, T Asakura, J Maruyama, Y Morita, H Oike, A Shimizu-Ibuka, ... Applied and Environmental Microbiology 72 (5), 3716-3723, 2006 | 80 | 2006 |
Hypothalamic neuronal circuits regulating hunger-induced taste modification O Fu, Y Iwai, M Narukawa, AW Ishikawa, KK Ishii, K Murata, Y Yoshimura, ... Nature communications 10 (1), 4560, 2019 | 63 | 2019 |
Crystal structure of neoculin: insights into its sweetness and taste-modifying activity A Shimizu-Ibuka, Y Morita, T Terada, T Asakura, K Nakajima, S Iwata, ... Journal of molecular biology 359 (1), 148-158, 2006 | 61 | 2006 |
SatB2-expressing neurons in the parabrachial nucleus encode sweet taste O Fu, Y Iwai, K Kondoh, T Misaka, Y Minokoshi, K Nakajima Cell reports 27 (6), 1650-1656. e4, 2019 | 52 | 2019 |
Acid‐induced sweetness of neoculin is ascribed to its pH‐dependent agonistic‐antagonistic interaction with human sweet taste receptor K Nakajima, Y Morita, A Koizumi, T Asakura, T Terada, K Ito, ... The FASEB Journal 22 (7), 2323-2330, 2008 | 38 | 2008 |
Neoculin, a taste-modifying protein, is recognized by human sweet taste receptor K Nakajima, T Asakura, H Oike, Y Morita, A Shimizu-Ibuka, T Misaka, ... Neuroreport 17 (12), 1241-1244, 2006 | 38 | 2006 |
Minireview: Novel Aspects of M3 Muscarinic Receptor Signaling in Pancreatic β-Cells K Nakajima, S Jain, I Ruiz de Azua, SM McMillin, M Rossi, J Wess Molecular endocrinology 27 (8), 1208-1216, 2013 | 28 | 2013 |
Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo IR De Azua, K Nakajima, M Rossi, Y Cui, W Jou, O Gavrilova, J Wess The FASEB Journal 26 (10), 4275, 2012 | 23 | 2012 |
Identification and modulation of the key amino acid residue responsible for the pH sensitivity of neoculin, a taste-modifying protein K Nakajima, K Yokoyama, T Koizumi, A Koizumi, T Asakura, T Terada, ... PloS one 6 (4), e19448, 2011 | 22 | 2011 |
Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin K Ito, T Sugawara, A Koizumi, K Nakajima, A Shimizu-Ibuka, M Shiroishi, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1800 (9), 986-992, 2010 | 20 | 2010 |
Recent advances in neural circuits for taste perception in hunger O Fu, Y Minokoshi, K Nakajima Frontiers in neural circuits 15, 609824, 2021 | 18 | 2021 |
A novel nipple–areola complex involvement predictive index for indicating nipple-sparing mastectomy in breast cancer patients H Seki, T Sakurai, S Mizuno, T Tokuda, T Kaburagi, M Seki, T Karahashi, ... Breast Cancer 26, 808-816, 2019 | 15 | 2019 |