| Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection TJ Hannan, M Totsika, KJ Mansfield, KH Moore, MA Schembri, ... FEMS microbiology reviews 36 (3), 616-648, 2012 | 480 | 2012 |
| Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection TJ Hannan, IU Mysorekar, CS Hung, ML Isaacson-Schmid, SJ Hultgren PLoS pathogens 6 (8), e1001042, 2010 | 328 | 2010 |
| Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted β strand displacement mechanism H Remaut, RJ Rose, TJ Hannan, SJ Hultgren, SE Radford, AE Ashcroft, ... Molecular cell 22 (6), 831-842, 2006 | 204 | 2006 |
| Drug and vaccine development for the treatment and prevention of urinary tract infections VP O’Brien, TJ Hannan, HV Nielsen, SJ Hultgren Microbiology spectrum 4 (1), 2016 | 195 | 2016 |
| Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection K Nagamatsu, TJ Hannan, RL Guest, M Kostakioti, M Hadjifrangiskou, ... Proceedings of the National Academy of Sciences 112 (8), E871-E880, 2015 | 182 | 2015 |
| A FimH Inhibitor Prevents Acute Bladder Infection and Treats Chronic Cystitis Caused by Multidrug-Resistant Uropathogenic Escherichia coli ST131 M Totsika, M Kostakioti, TJ Hannan, M Upton, SA Beatson, JW Janetka, ... The Journal of infectious diseases 208 (6), 921-928, 2013 | 154 | 2013 |
| Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections HL Schreiber, MS Conover, WC Chou, ME Hibbing, AL Manson, ... Science translational medicine 9 (382), eaaf1283, 2017 | 152 | 2017 |
| Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections PS Guiton, TJ Hannan, B Ford, MG Caparon, SJ Hultgren Infection and immunity 81 (1), 329-339, 2013 | 115 | 2013 |
| Inhibition of cyclooxygenase-2 prevents chronic and recurrent cystitis TJ Hannan, PL Roberts, TE Riehl, S van der Post, JM Binkley, ... EBioMedicine 1 (1), 46-57, 2014 | 113 | 2014 |
| Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections L Mydock-McGrane, Z Cusumano, Z Han, J Binkley, M Kostakioti, ... Journal of medicinal chemistry 59 (20), 9390-9408, 2016 | 112 | 2016 |
| Rational design strategies for FimH antagonists: new drugs on the horizon for urinary tract infection and Crohn’s disease LK Mydock-McGrane, TJ Hannan, JW Janetka Expert opinion on drug discovery 12 (7), 711-731, 2017 | 96 | 2017 |
| A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease VP O'brien, TJ Hannan, L Yu, J Livny, EDO Roberson, DJ Schwartz, ... Nature microbiology 2 (1), 1-10, 2016 | 96 | 2016 |
| LeuX tRNA‐dependent and ‐independent mechanisms of Escherichia coli pathogenesis in acute cystitis TJ Hannan, IU Mysorekar, SL Chen, JN Walker, JM Jones, JS Pinkner, ... Molecular microbiology 67 (1), 116-128, 2008 | 84 | 2008 |
| Role of hypoxia inducible factor-1α (HIF-1α) in innate defense against uropathogenic Escherichia coli infection AE Lin, FC Beasley, J Olson, N Keller, RA Shalwitz, TJ Hannan, ... PLoS pathogens 11 (4), e1004818, 2015 | 83 | 2015 |
| Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection VP O’Brien, TJ Hannan, AJ Schaeffer, SJ Hultgren Current opinion in infectious diseases 28 (1), 97, 2015 | 71 | 2015 |
| Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection DJ Schwartz, MS Conover, TJ Hannan, SJ Hultgren PLoS pathogens 11 (1), e1004599, 2015 | 67 | 2015 |
| Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity LW Goneau, TJ Hannan, RA MacPhee, DJ Schwartz, JM Macklaim, ... MBio 6 (2), e00356-15, 2015 | 62 | 2015 |
| A Murine Model for Escherichia coli Urinary Tract Infection TJ Hannan, DA Hunstad Bacterial Persistence, 159-175, 2016 | 59 | 2016 |
| Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions V Kalas, JS Pinkner, TJ Hannan, ME Hibbing, KW Dodson, AS Holehouse, ... Science advances 3 (2), e1601944, 2017 | 52 | 2017 |
| Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection M Kostakioti, M Hadjifrangiskou, CK Cusumano, TJ Hannan, JW Janetka, ... Infection and immunity 80 (8), 2826-2834, 2012 | 50 | 2012 |
