| Endocrine disrupting chemicals targeting estrogen receptor signaling: identification and mechanisms of action EK Shanle, W Xu Chemical research in toxicology 24 (1), 6-19, 2011 | 593 | 2011 |
| SIRT1 is essential for normal cognitive function and synaptic plasticity S Michán, Y Li, MMH Chou, E Parrella, H Ge, JM Long, JS Allard, K Lewis, ... Journal of Neuroscience 30 (29), 9695-9707, 2010 | 575 | 2010 |
| A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase DJ Hazuda, NJ Anthony, RP Gomez, SM Jolly, JS Wai, L Zhuang, ... Proceedings of the National Academy of Sciences 101 (31), 11233-11238, 2004 | 418 | 2004 |
| CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis L Wang, Z Zhao, MB Meyer, S Saha, M Yu, A Guo, KB Wisinski, W Huang, ... Cancer cell 25 (1), 21-36, 2014 | 306 | 2014 |
| TDRD3 is an effector molecule for arginine-methylated histone marks Y Yang, Y Lu, A Espejo, J Wu, W Xu, S Liang, MT Bedford Molecular cell 40 (6), 1016-1023, 2010 | 247 | 2010 |
| PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis F Liu, F Ma, Y Wang, L Hao, H Zeng, C Jia, Y Wang, P Liu, IM Ong, B Li, ... Nature cell biology 19 (11), 1358-1370, 2017 | 229 | 2017 |
| Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ... Nature cell biology 22 (9), 1064-1075, 2020 | 226 | 2020 |
| Selectively targeting estrogen receptors for cancer treatment EK Shanle, W Xu Advanced drug delivery reviews 62 (13), 1265-1276, 2010 | 156 | 2010 |
| Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers E Powell, W Xu Proceedings of the National Academy of Sciences 105 (48), 19012-19017, 2008 | 135 | 2008 |
| Phosphorylation-mediated inactivation of coactivator-associated arginine methyltransferase 1 K Higashimoto, P Kuhn, D Desai, X Cheng, W Xu Proceedings of the National Academy of Sciences 104 (30), 12318-12323, 2007 | 130 | 2007 |
| Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition E Shishkova, H Zeng, F Liu, NW Kwiecien, AS Hebert, JJ Coon, W Xu Nature communications 8 (1), 15571, 2017 | 122 | 2017 |
| CARM1 is an important determinant of ERα-dependent breast cancer cell differentiation and proliferation in breast cancer cells M Al-Dhaheri, J Wu, GP Skliris, J Li, K Higashimato, Y Wang, KP White, ... Cancer research 71 (6), 2118-2128, 2011 | 105 | 2011 |
| Automethylation of CARM1 allows coupling of transcription and mRNA splicing P Kuhn, R Chumanov, Y Wang, Y Ge, RR Burgess, W Xu Nucleic acids research 39 (7), 2717-2726, 2011 | 97 | 2011 |
| Aminoflavone-loaded EGFR-targeted unimolecular micelle nanoparticles exhibit anti-cancer effects in triple negative breast cancer AM Brinkman, G Chen, Y Wang, CJ Hedman, NM Sherer, TC Havighurst, ... Biomaterials 101, 20-31, 2016 | 94 | 2016 |
| Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription J Wu, W Xu Proceedings of the National Academy of Sciences 109 (15), 5675-5680, 2012 | 94 | 2012 |
| Quantum-dot-based theranostic micelles conjugated with an anti-EGFR nanobody for triple-negative breast cancer therapy Y Wang, Y Wang, G Chen, Y Li, W Xu, S Gong ACS applied materials & interfaces 9 (36), 30297-30305, 2017 | 88 | 2017 |
| Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ E Powell, E Shanle, A Brinkman, J Li, S Keles, KB Wisinski, W Huang, ... PloS one 7 (2), e30993, 2012 | 88 | 2012 |
| Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells EK Shanle, Z Zhao, J Hawse, K Wisinski, S Keles, M Yuan, W Xu Molecular endocrinology 27 (10), 1762-1775, 2013 | 82 | 2013 |
| Nuclear Receptor Cofactors in PPARγ‐Mediated Adipogenesis and Adipocyte Energy Metabolism E Powell, P Kuhn, W Xu PPAR research 2007 (1), 053843, 2007 | 82 | 2007 |
| MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs L Wang, H Zeng, Q Wang, Z Zhao, TG Boyer, X Bian, W Xu Science advances 1 (9), e1500463, 2015 | 78 | 2015 |
