| ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles Y Shimizu, D Thumkeo, J Keel, T Ishizaki, H Oshima, M Oshima, Y Noda, ... The Journal of cell biology 168 (6), 941-953, 2005 | 348 | 2005 |
| Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death D Thumkeo, J Keel, T Ishizaki, M Hirose, K Nonomura, H Oshima, ... Molecular and cellular biology 23 (14), 5043-5055, 2003 | 306 | 2003 |
| Physiological roles of Rho and Rho effectors in mammals D Thumkeo, S Watanabe, S Narumiya European journal of cell biology 92 (10-11), 303-315, 2013 | 263 | 2013 |
| Rho signaling research: history, current status and future directions S Narumiya, D Thumkeo FEBS letters 592 (11), 1763-1776, 2018 | 177 | 2018 |
| ROCK‐I and ROCK‐II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo D Thumkeo, Y Shimizu, S Sakamoto, S Yamada, S Narumiya Genes to Cells 10 (8), 825-834, 2005 | 169 | 2005 |
| A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors R Shinohara, D Thumkeo, H Kamijo, N Kaneko, K Sawamoto, ... Nature neuroscience 15 (3), 373-380, 2012 | 137 | 2012 |
| T cell–intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell–driven inflammation J Lee, T Aoki, D Thumkeo, R Siriwach, C Yao, S Narumiya Journal of Allergy and Clinical Immunology 143 (2), 631-643, 2019 | 106 | 2019 |
| Constitutive activation of DIA 1 (DIAPH 1) via C‐terminal truncation causes human sensorineural hearing loss T Ueyama, Y Ninoyu, S Nishio, T Miyoshi, H Torii, K Nishimura, ... EMBO molecular medicine 8 (11), 1310-1324, 2016 | 65 | 2016 |
| PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment D Thumkeo, S Punyawatthananukool, S Prasongtanakij, R Matsuura, ... Cell reports 39 (10), 2022 | 56 | 2022 |
| Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia D Thumkeo, R Shinohara, K Watanabe, H Takebayashi, Y Toyoda, ... PLoS One 6 (9), e25465, 2011 | 56 | 2011 |
| Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK‐I and ROCK‐II H Kamijo, Y Matsumura, D Thumkeo, S Koike, M Masu, Y Shimizu, ... Genes to Cells 16 (10), 1012-1021, 2011 | 42 | 2011 |
| DIAPH1 variants in non–east asian patients with sporadic moyamoya disease AJ Kundishora, ST Peters, A Pinard, D Duran, S Panchagnula, T Barak, ... JAMA neurology 78 (8), 993-1003, 2021 | 35 | 2021 |
| LPA induces keratinocyte differentiation and promotes skin barrier function through the LPAR1/LPAR5-RHO-ROCK-SRF axis A Sumitomo, R Siriwach, D Thumkeo, K Ito, R Nakagawa, N Tanaka, ... Journal of Investigative Dermatology 139 (5), 1010-1022, 2019 | 32 | 2019 |
| Moesin controls clathrin-mediated S1PR1 internalization in T cells A Nomachi, M Yoshinaga, J Liu, P Kanchanawong, K Tohyama, ... PLoS One 8 (12), e82590, 2013 | 27 | 2013 |
| DAAM2 variants cause nephrotic syndrome via actin dysregulation R Schneider, K Deutsch, GJ Hoeprich, J Marquez, T Hermle, DA Braun, ... The American Journal of Human Genetics 107 (6), 1113-1128, 2020 | 26 | 2020 |
| mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility S Sakamoto, D Thumkeo, H Ohta, Z Zhang, S Huang, P Kanchanawong, ... PLoS biology 16 (9), e2004874, 2018 | 24 | 2018 |
| mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse D Thumkeo, Y Katsura, Y Nishimura, P Kanchanawong, K Tohyama, ... Science advances 6 (1), eaay2432, 2020 | 15 | 2020 |
| EphA4‐dependent axon retraction and midline localization of E phrin‐B 3 are disrupted in the spinal cord of mice lacking mD ia1 and mD ia3 in combination Y Toyoda, R Shinohara, D Thumkeo, H Kamijo, H Nishimaru, H Hioki, ... Genes to Cells 18 (10), 873-885, 2013 | 14 | 2013 |
| LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation KN Kremer, A Buser, D Thumkeo, S Narumiya, J Jacobelli, R Pelanda, ... Proceedings of the National Academy of Sciences 119 (15), e2118816119, 2022 | 13 | 2022 |
| Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction I Abe, T Terabayashi, K Hanada, H Kondo, Y Teshima, Y Ishii, M Miyoshi, ... Cardiovascular Research 117 (4), 1103-1117, 2021 | 11 | 2021 |
