Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor JP Coppé, CK Patil, F Rodier, Y Sun, DP Muñoz, J Goldstein, PS Nelson, ... PLoS biology 6 (12), e301, 2008 | 4064 | 2008 |
Four faces of cellular senescence F Rodier, J Campisi The Journal of cell biology 192 (4), 547-556, 2011 | 2343 | 2011 |
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion F Rodier, JP Coppé, CK Patil, WAM Hoeijmakers, DP Muñoz, SR Raza, ... Nature cell biology 11 (8), 973, 2009 | 2288 | 2009 |
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ... Developmental cell 31 (6), 722-733, 2014 | 1806 | 2014 |
A versatile viral system for expression and depletion of proteins in mammalian cells E Campeau, VE Ruhl, F Rodier, CL Smith, BL Rahmberg, JO Fuss, ... PLoS One 4 (8), e6529, 2009 | 986 | 2009 |
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion F Rodier, DP Muñoz, R Teachenor, V Chu, O Le, D Bhaumik, JP Coppé, ... J Cell Sci 124 (1), 68-81, 2011 | 609 | 2011 |
MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8 D Bhaumik, GK Scott, S Schokrpur, CK Patil, AV Orjalo, F Rodier, ... Aging 1 (4), 402, 2009 | 568 | 2009 |
Two faces of p53: aging and tumor suppression F Rodier, J Campisi, D Bhaumik Nucleic Acids Research 35 (22), 7475-7484, 2007 | 530 | 2007 |
Tumor suppressor and aging biomarker p16INK4a induces cellular senescence without the associated inflammatory secretory phenotype JP Coppé, F Rodier, CK Patil, A Freund, PY Desprez, J Campisi Journal of Biological Chemistry 286 (42), 36396-36403, 2011 | 521 | 2011 |
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen JP Coppé, CK Patil, F Rodier, A Krtolica, CM Beauséjour, S Parrinello, ... PLoS One 5 (2), e9188, 2010 | 502 | 2010 |
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes AR Davalos, M Kawahara, GK Malhotra, N Schaum, J Huang, U Ved, ... J Cell Biol 201 (4), 613-629, 2013 | 443 | 2013 |
Designing a broad-spectrum integrative approach for cancer prevention and treatment KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ... Seminars in cancer biology 35, S276-S304, 2015 | 344* | 2015 |
Keeping the senescence secretome under control: molecular reins on the senescence-associated secretory phenotype N Malaquin, A Martinez, F Rodier Experimental gerontology 82, 39-49, 2016 | 244 | 2016 |
Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype RM Laberge, L Zhou, MR Sarantos, F Rodier, A Freund, PLJ de Keizer, ... Aging Cell 11 (4), 569-578, 2012 | 239 | 2012 |
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status ONL Le, F Rodier, F Fontaine, JP Coppe, J Campisi, J DeGregori, ... Aging cell 9 (3), 398-409, 2010 | 189 | 2010 |
Cancer and aging: the importance of telomeres in genome maintenance F Rodier, SH Kim, T Nijjar, P Yaswen, J Campisi The international journal of biochemistry & cell biology 37 (5), 977-990, 2005 | 182 | 2005 |
Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence H Fleury, N Malaquin, V Tu, S Gilbert, A Martinez, MA Olivier, A Sauriol, ... Nature Communications 10 (1), 2556, 2019 | 177 | 2019 |
The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity W Chatoo, M Abdouh, J David, MP Champagne, J Ferreira, F Rodier, ... Journal of Neuroscience 29 (2), 529-542, 2009 | 154 | 2009 |
The Autophagy-Senescence Connection in Chemotherapy: Must Tumor Cells (Self) Eat Before They Sleep? RW Goehe, X Di, K Sharma, ML Bristol, SC Henderson, K Valerie, ... Journal of Pharmacology and Experimental Therapeutics 343 (3), 763-778, 2012 | 145 | 2012 |
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lopez, M Kawahara, ... JCI insight 4 (14), 2019 | 122 | 2019 |