| Glycopeptide and lipoglycopeptide antibiotics D Kahne, C Leimkuhler, W Lu, C Walsh Chemical reviews 105 (2), 425-448, 2005 | 848 | 2005 |
| The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment CL Grimes, LDZ Ariyananda, JE Melnyk, EK O’Shea Journal of the American Chemical Society 134 (33), 13535-13537, 2012 | 229 | 2012 |
| Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications H Liang, KE DeMeester, CW Hou, MA Parent, JL Caplan, CL Grimes Nature communications 8 (1), 15015, 2017 | 141 | 2017 |
| A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases M Oberthür, C Leimkuhler, RG Kruger, W Lu, CT Walsh, D Kahne Journal of the American Chemical Society 127 (30), 10747-10752, 2005 | 101 | 2005 |
| AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A W Lu, C Leimkuhler, GJ Gatto, RG Kruger, M Oberthu, D Kahne, CT Walsh Chemistry & biology 12 (5), 527-534, 2005 | 88 | 2005 |
| Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin W Lu, M Oberthür, C Leimkuhler, J Tao, D Kahne, CT Walsh Proceedings of the National Academy of Sciences 101 (13), 4390-4395, 2004 | 77 | 2004 |
| Synthesis of Functionalized N-Acetyl Muramic Acids To Probe Bacterial Cell Wall Recycling and Biosynthesis KE DeMeester, H Liang, MR Jensen, ZS Jones, EA D’Ambrosio, SL Scinto, ... Journal of the American Chemical Society 140 (30), 9458-9465, 2018 | 75 | 2018 |
| AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A W Lu, C Leimkuhler, M Oberthür, D Kahne, CT Walsh Biochemistry 43 (15), 4548-4558, 2004 | 66 | 2004 |
| Kinetic Characterization of the Glycosyltransferase Module of Staphylococcus aureus PBP2 D Barrett, C Leimkuhler, L Chen, D Walker, D Kahne, S Walker Journal of bacteriology 187 (6), 2215-2217, 2005 | 65 | 2005 |
| In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides Y Yuan, HS Chung, C Leimkuhler, CT Walsh, D Kahne, S Walker Journal of the American Chemical Society 127 (41), 14128-14129, 2005 | 64 | 2005 |
| A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW X Yang, R McQuillen, Z Lyu, P Phillips-Mason, A De La Cruz, ... Nature microbiology 6 (5), 584-593, 2021 | 63 | 2021 |
| Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori JA Taylor, BP Bratton, SR Sichel, KM Blair, HM Jacobs, KE DeMeester, ... elife 9, e52482, 2020 | 60 | 2020 |
| Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics C Leimkuhler, L Chen, D Barrett, G Panzone, B Sun, B Falcone, ... Journal of the American Chemical Society 127 (10), 3250-3251, 2005 | 59 | 2005 |
| Degradation and reconstruction of moenomycin A and derivatives: dissecting the function of the isoprenoid chain M Adachi, Y Zhang, C Leimkuhler, B Sun, JV LaTour, DE Kahne Journal of the American Chemical Society 128 (43), 14012-14013, 2006 | 58 | 2006 |
| Molecular recognition of muramyl dipeptide occurs in the leucine-rich repeat domain of Nod2 ML Lauro, EA D’Ambrosio, BJ Bahnson, CL Grimes ACS infectious diseases 3 (4), 264-270, 2017 | 57 | 2017 |
| Peptidoglycan modifications tune the stability and function of the innate immune receptor Nod2 JE Melnyk, V Mohanan, AK Schaefer, CW Hou, CL Grimes Journal of the American Chemical Society 137 (22), 6987-6990, 2015 | 55 | 2015 |
| A practical method for the stereoselective generation of β-2-deoxy glycosyl phosphates M Oberthür, C Leimkuhler, D Kahne Organic Letters 6 (17), 2873-2876, 2004 | 48 | 2004 |
| The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease V Mohanan, CL Grimes Journal of Biological Chemistry 289 (27), 18987-18998, 2014 | 47 | 2014 |
| The effect of NOD2 on the microbiota in Crohn's disease ML Lauro, JM Burch, CL Grimes Current opinion in biotechnology 40, 97-102, 2016 | 44 | 2016 |
| Bacterial peptidoglycan fragments differentially regulate innate immune signaling KL Bersch, KE DeMeester, R Zagani, S Chen, KA Wodzanowski, S Liu, ... ACS central science 7 (4), 688-696, 2021 | 41 | 2021 |
