Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents M Roberti, D Pizzirani, D Simoni, R Rondanin, R Baruchello, C Bonora, ... Journal of medicinal chemistry 46 (16), 3546-3554, 2003 | 302 | 2003 |
Pterostilbene and 3′-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells M Tolomeo, S Grimaudo, A Di Cristina, M Roberti, D Pizzirani, M Meli, ... The international journal of biochemistry & cell biology 37 (8), 1709-1726, 2005 | 203 | 2005 |
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines D Simoni, G Grisolia, G Giannini, M Roberti, R Rondanin, L Piccagli, ... Journal of medicinal chemistry 48 (3), 723-736, 2005 | 196 | 2005 |
Multitarget drug design strategy: quinone–tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects E Nepovimova, E Uliassi, J Korabecny, LE Pena-Altamira, S Samez, ... Journal of medicinal chemistry 57 (20), 8576-8589, 2014 | 189 | 2014 |
Galloflavin (CAS 568‐80‐9): a novel inhibitor of lactate dehydrogenase M Manerba, M Vettraino, L Fiume, G Di Stefano, A Sartini, E Giacomini, ... ChemMedChem 7 (2), 311-317, 2012 | 182 | 2012 |
Non-ATP competitive protein kinase inhibitors L Garuti, M Roberti, G Bottegoni Current medicinal chemistry 17 (25), 2804-2821, 2010 | 166 | 2010 |
Irreversible protein kinase inhibitors L Garuti, M Roberti, G Bottegoni Current medicinal chemistry 18 (20), 2981-2994, 2011 | 142 | 2011 |
Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways F Farabegoli, M Vettraino, M Manerba, L Fiume, M Roberti, G Di Stefano European Journal of Pharmaceutical Sciences 47 (4), 729-738, 2012 | 141 | 2012 |
Tetramethylguanidine (TMG)-catalyzed addition of dialkyl phosphites to α, β-unsaturated carbonyl compounds, alkenenitriles, aldehydes, ketones and imines D Simoni, FP Invidiata, M Manferdini, I Lampronti, R Rondanin, M Roberti, ... Tetrahedron letters 39 (41), 7615-7618, 1998 | 140 | 1998 |
Strong bicyclic guanidine base-promoted Wittig and Horner− Wadsworth− Emmons reactions D Simoni, M Rossi, R Rondanin, A Mazzali, R Baruchello, C Malagutti, ... Organic letters 2 (24), 3765-3768, 2000 | 136 | 2000 |
Berberine and its metabolites: relationship between physicochemical properties and plasma levels after administration to human subjects S Spinozzi, C Colliva, C Camborata, M Roberti, C Ianni, F Neri, ... Journal of Natural Products 77 (4), 766-772, 2014 | 133 | 2014 |
Synthesis and antiproliferative activity of some benzimidazole-4, 7-dione derivatives L Garuti, M Roberti, M Malagoli, T Rossi, M Castelli Bioorganic & medicinal chemistry letters 10 (19), 2193-2195, 2000 | 126 | 2000 |
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells D Simoni, M Roberti, FP Invidiata, R Rondanin, R Baruchello, C Malagutti, ... Journal of medicinal chemistry 44 (14), 2308-2318, 2001 | 116 | 2001 |
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease J Jeřábek, E Uliassi, L Guidotti, J Korábečný, O Soukup, V Sepsova, ... European Journal of Medicinal Chemistry 127, 250-262, 2017 | 114 | 2017 |
Nitrogen-containing heterocyclic quinones: a class of potential selective antitumor agents. L Garuti, M Roberti, D Pizzirani Mini Reviews in Medicinal Chemistry 7 (5), 481-489, 2007 | 107 | 2007 |
Synthesis and antiviral activity of some N-benzenesulphonylbenzimidazoles L Garuti, M Roberti, C Cermelli Bioorganic & medicinal chemistry letters 9 (17), 2525-2530, 1999 | 107 | 1999 |
Identification of biphenyl-based hybrid molecules able to decrease the intracellular level of Bcl-2 protein in Bcl-2 overexpressing leukemia cells D Pizzirani, M Roberti, S Grimaudo, A Di Cristina, RM Pipitone, ... Journal of medicinal chemistry 52 (21), 6936-6940, 2009 | 105 | 2009 |
Identification of a Terphenyl Derivative that Blocks the Cell Cycle in the G0−G1 Phase and Induces Differentiation in Leukemia Cells M Roberti, D Pizzirani, M Recanatini, D Simoni, S Grimaudo, D Cristina, ... Journal of medicinal chemistry 49 (10), 3012-3018, 2006 | 103 | 2006 |
Antioxidant activity of hydroxystilbene derivatives in homogeneous solution R Amorati, M Lucarini, V Mugnaini, GF Pedulli, M Roberti, D Pizzirani The Journal of organic chemistry 69 (21), 7101-7107, 2004 | 103 | 2004 |
Stilbene-based anticancer agents: resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism D Simoni, M Roberti, FP Invidiata, E Aiello, S Aiello, P Marchetti, ... Bioorganic & Medicinal Chemistry Letters 16 (12), 3245-3248, 2006 | 99 | 2006 |