Early phase drug discovery: cheminformatics and computational techniques in identifying lead series BC Duffy, L Zhu, H Decornez, DB Kitchen Bioorganic & medicinal chemistry 20 (18), 5324-5342, 2012 | 108 | 2012 |
Analysis of Cannabinoid-Containing Fluids in Illicit Vaping Cartridges Recovered from Pulmonary Injury Patients: Identification of Vitamin E Acetate as a Major Diluent B Duffy, L Li, S Lu, L Durocher, M Dittmar, E Delaney-Baldwin, ... Toxics 8 (1), 8, 2020 | 99 | 2020 |
Cyclic amines as bromodomain inhibitors DJ Fairfax, BC Duffy, GS Martin, JF Quinn, S Liu, GS Wagner, PR Young US Patent 9,073,878, 2015 | 47 | 2015 |
Heterocyclic compounds as bromodomain inhibitors S Liu, BC Duffy, JF Quinn, MX Jiang, R Wang, GS Martin, H Zhao, ... US Patent 9,271,978, 2016 | 43 | 2016 |
Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine OA Kharenko, RG Patel, SD Brown, C Calosing, A White, ... Journal of medicinal chemistry 61 (18), 8202-8211, 2018 | 42 | 2018 |
Total synthesis of (±)-cameroonan-7α-ol and biomimetic rearrangements to related nopsane sesquiterpenes CE Davis, BC Duffy, RM Coates The Journal of organic chemistry 68 (18), 6935-6943, 2003 | 42 | 2003 |
Bicyclic bromodomain inhibitors JF Quinn, BC Duffy, S Liu, R Wang, MX Jiang, GS Martin, GS Wagner, ... US Patent 9,663,520, 2017 | 38 | 2017 |
Total synthesis of Resolvin E1 M Allard, K Barnes, X Chen, YY Cheung, B Duffy, C Heap, J Inthavongsay, ... Tetrahedron letters 52 (21), 2623-2626, 2011 | 35 | 2011 |
Substituted pyridines as bromodomain inhibitors MX JIANG, BF Molino, S Liu, R Wang, BC Duffy, JF Quinn, GS Wagner US Patent App. 10/179,125, 2019 | 34* | 2019 |
Biaryl derivatives as bromodomain inhibitors DJ Fairfax, GS Martin, JF Quinn, BC Duffy, GS Wagner, PR Young US Patent 9,765,039, 2017 | 31 | 2017 |
Discovery of a new chemical series of BRD4 (1) inhibitors using protein-ligand docking and structure-guided design BC Duffy, S Liu, GS Martin, R Wang, MM Hsia, H Zhao, C Guo, M Ellis, ... Bioorganic & medicinal chemistry letters 25 (14), 2818-2823, 2015 | 30 | 2015 |
Substituted bicyclic compounds as bromodomain inhibitors S Liu, JF Quinn, BC Duffy, R Wang, MX Jiang, GS Martin, H Zhao, M Ellis, ... US Patent 9,662,311, 2017 | 29 | 2017 |
Lead Optimization toward Proof-of-Concept Tools for Huntington’s Disease within a 4-(1H-Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors J Wityak, KF McGee, MP Conlon, RH Song, BC Duffy, B Clayton, M Lynch, ... Journal of medicinal chemistry 58 (7), 2967-2987, 2015 | 29 | 2015 |
Cyclic amines as bromodomain inhibitors DJ Fairfax, BC Duffy, GS Martin, JF Quinn, S Liu, GS Wagner, PR Young US Patent 9,278,940, 2016 | 25 | 2016 |
Heterocyclic compounds as bromodomain inhibitors S Liu, BC Duffy, JF Quinn, MX Jiang, R Wang, GS Martin, H Zhao, ... US Patent 9,861,637, 2018 | 24 | 2018 |
Substituted bicyclic compounds as bromodomain inhibitors S Liu, JF Quinn, BC Duffy, R Wang, MX Jiang, GS Martin, H Zhao, M Ellis, ... US Patent 9,636,328, 2017 | 22 | 2017 |
Total Synthesis of (±)-Cameroonanol CE Davis, BC Duffy, RM Coates Organic letters 2 (17), 2717-2719, 2000 | 22 | 2000 |
Discovery of small molecule antibiotics against a unique tRNA‐mediated regulation of transcription in Gram‐positive bacteria KM Frohlich, S Weintraub, JT Bell, GC Todd, VYP Väre, R Schneider, ... ChemMedChem, 2019 | 21 | 2019 |
SUBSTITUTED PYRIDINES AS BROMODOMAiN INHIBITORS MX Jiang, BF Molino, S Liu, R Wang, BC Duffy, JF Quinn, GS Wagner US Patent App. 15/531,204, 2017 | 16 | 2017 |
Potency Analysis of Medical Marijuana Products from New York State L Li, BC Duffy, LA Durocher, MA Dittmar, RA Acosta, ER Delaney, L Li, ... Cannabis and cannabinoid research 4 (3), 195-203, 2019 | 15 | 2019 |