Genomic integrity and the ageing brain H Chow, K Herrup Nature Reviews Neuroscience 16 (11), 672-684, 2015 | 192 | 2015 |
Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury M Zhou, A Xu, PKH Tam, KSL Lam, L Chan, RLC Hoo, J Liu, KHM Chow, ... Hepatology 48 (4), 1087-1096, 2008 | 122 | 2008 |
Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence HM Chow, M Shi, A Cheng, Y Gao, G Chen, X Song, RWL So, J Zhang, ... Nature neuroscience 22 (11), 1806-1819, 2019 | 110 | 2019 |
A gold (III) porphyrin complex with antitumor properties targets the Wnt/β-catenin pathway KHM Chow, RWY Sun, JBB Lam, CKL Li, A Xu, DL Ma, R Abagyan, ... Cancer research 70 (1), 329-337, 2010 | 106 | 2010 |
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities JBB Lam, KHM Chow, A Xu, KSL Lam, J Liu, NS Wong, RT Moon, ... PloS one 4 (3), e4968, 2009 | 100 | 2009 |
CDK5 activator protein p25 preferentially binds and activates GSK3β HM Chow, D Guo, JC Zhou, GY Zhang, HF Li, K Herrup, J Zhang Proceedings of the National Academy of Sciences 111 (45), E4887-E4895, 2014 | 72 | 2014 |
ATM is activated by ATP depletion and modulates mitochondrial function through NRF1 HM Chow, A Cheng, X Song, MR Swerdel, RP Hart, K Herrup Journal of Cell Biology 218 (3), 909-928, 2019 | 68 | 2019 |
Adiponectin stimulates Wnt inhibitory factor-1 expression through epigenetic regulations involving the transcription factor specificity protein 1 J Liu, JBB Lam, KHM Chow, A Xu, KSL Lam, RT Moon, Y Wang Carcinogenesis 29 (11), 2195-2202, 2008 | 65 | 2008 |
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance L Leng, Z Yuan, R Pan, X Su, H Wang, J Xue, K Zhuang, J Gao, Z Chen, ... Nature Metabolism 4 (10), 1287-1305, 2022 | 51 | 2022 |
ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations A Cheng, T Zhao, KH Tse, HM Chow, Y Cui, L Jiang, S Du, MMT Loy, ... Proceedings of the National Academy of Sciences 115 (2), E292-E301, 2018 | 45 | 2018 |
ATM loss disrupts the autophagy-lysosomal pathway A Cheng, KH Tse, HM Chow, Y Gan, X Song, F Ma, YXY Qian, W She, ... Autophagy 17 (8), 1998-2010, 2021 | 40 | 2021 |
The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment J Chen, Y Chen, G Vail, H Chow, Y Zhang, L Louie, J Li, RP Hart, ... Molecular neurodegeneration 11, 1-14, 2016 | 38 | 2016 |
Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease Y Zhang, Z Zhang, L Li, K Xu, Z Ma, HM Chow, K Herrup, J Li The FASEB Journal 34 (12), 16364-16382, 2020 | 35 | 2020 |
Empowering 8 billion minds: Enabling better mental health for all via the ethical adoption of technologies PM Doraiswamy, E London, P Varnum, B Harvey, S Saxena, S Tottman, ... NAM perspectives 2019, 2019 | 34 | 2019 |
Cyclin-dependent kinase 5–dependent BAG3 degradation modulates synaptic protein turnover J Zhou, HM Chow, Y Liu, D Wu, M Shi, J Li, L Wen, Y Gao, G Chen, ... Biological psychiatry 87 (8), 756-769, 2020 | 27 | 2020 |
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration S Peng, P Guo, X Lin, Y An, KH Sze, MHY Lau, ZS Chen, Q Wang, W Li, ... Proceedings of the National Academy of Sciences 118 (19), e2022940118, 2021 | 20 | 2021 |
P2‐121: Senescent Neurons in the Alzheimer's Brain Kill Nearby Healthy Neurons by Blocking their WNT Lifeline: The Continuing Saga of the Zombie Apocalypse HM Chow, KH Tse, K Herrup Alzheimer's & Dementia 12, P658-P658, 2016 | 19 | 2016 |
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons JKL Sun, D Wu, GCN Wong, TM Lau, M Yang, RP Hart, KM Kwan, ... Aging cell 22 (2), e13772, 2023 | 13 | 2023 |
Adrenomedullin and its receptor components in adipose tissues: Differences between white and brown fats and the effects of adrenergic stimulation AGG Go, KHM Chow, ISS Hwang, F Tang peptides 28 (4), 920-927, 2007 | 12 | 2007 |
DNA damage response-associated cell cycle re-entry and neuronal senescence in brain aging and Alzheimer’s disease GCN Wong, KHM Chow Journal of Alzheimer's Disease, 1-23, 2022 | 10 | 2022 |