Type 2 diabetes–associated genetic variants regulate chromatin accessibility in human islets S Khetan, R Kursawe, A Youn, N Lawlor, A Jillette, EJ Marquez, D Ucar, ... Diabetes 67 (11), 2466-2477, 2018 | 70 | 2018 |
Genomics of islet (dys) function and type 2 diabetes N Lawlor, S Khetan, D Ucar, ML Stitzel Trends in Genetics 33 (4), 244-255, 2017 | 69 | 2017 |
A common type 2 diabetes risk variant potentiates activity of an evolutionarily conserved islet stretch enhancer and increases C2CD4A and C2CD4B expression I Kycia, BN Wolford, JR Huyghe, C Fuchsberger, S Vadlamudi, R Kursawe, ... The American Journal of Human Genetics 102 (4), 620-635, 2018 | 46 | 2018 |
A neural network based model effectively predicts enhancers from clinical ATAC-seq samples A Thibodeau, A Uyar, S Khetan, ML Stitzel, D Ucar Scientific reports 8 (1), 16048, 2018 | 27 | 2018 |
Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation S Khetan, S Kales, R Kursawe, A Jillette, JC Ulirsch, SK Reilly, D Ucar, ... Nature communications 12 (1), 5242, 2021 | 16 | 2021 |
CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data A Thibodeau, S Khetan, A Eroglu, R Tewhey, ML Stitzel, D Ucar PLoS Computational Biology 17 (12), e1009670, 2021 | 11 | 2021 |
Chromatin accessibility profiling uncovers genetic- and T2D disease state-associated changes in cis-regulatory element use in human islets S Khetan, R Kursawe, A Youn, N Lawlor, EM Campos, D Ucar, ML Stitzel BioRxiv, 192922, 2017 | 3 | 2017 |
Functional characterization of thousands of type 2 diabetes-associated and chromatin-modulating variants under steady state and endoplasmic reticulum stress S Khetan, S Kales, R Kursawe, A Jillette, SK Reilly, D Ucar, R Tewhey, ... bioRxiv, 2020.02. 12.939348, 2020 | 1 | 2020 |
Overlapping binding sites underlie TF genomic occupancy S Khetan, ML Bulyk bioRxiv, 2024.03. 05.583629, 2024 | | 2024 |
Deciphering Type 2 Diabetes-associated SNP Effects on Islet Chromatin Accessibility and Beta Cell Expression Levels Using Functional Genomics S Khetan | | 2020 |