Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress TA Seimon, MJ Nadolski, X Liao, J Magallon, M Nguyen, NT Feric, ... Cell metabolism 12 (5), 467-482, 2010 | 545 | 2010 |
Mechanisms and consequences of macrophage apoptosis in atherosclerosis T Seimon, I Tabas Journal of lipid research 50, S382-S387, 2009 | 500 | 2009 |
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways JM Timmins, L Ozcan, TA Seimon, G Li, C Malagelada, J Backs, T Backs, ... The Journal of clinical investigation 119 (10), 2925-2941, 2009 | 472 | 2009 |
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-α and interleukin-6: model of NF-κB-and map kinase-dependent inflammation in advanced … Y Li, RF Schwabe, T DeVries-Seimon, PM Yao, MC Gerbod-Giannone, ... Journal of Biological Chemistry 280 (23), 21763-21772, 2005 | 444 | 2005 |
Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor T DeVries-Seimon, Y Li, PM Yao, E Stone, Y Wang, RJ Davis, R Flavell, ... The Journal of cell biology 171 (1), 61-73, 2005 | 414 | 2005 |
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe−/− and Ldlr−/− mice lacking CHOP E Thorp, G Li, TA Seimon, G Kuriakose, D Ron, I Tabas Cell metabolism 9 (5), 474-481, 2009 | 397 | 2009 |
Upward range extension of Andean anurans and chytridiomycosis to extreme elevations in response to tropical deglaciation TA Seimon, A Seimon, P Daszak, SRP Halloy, LM Schloegel, CA Aguilar, ... Global Change Biology 13 (1), 288-299, 2007 | 329 | 2007 |
Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions S Han, CP Liang, T DeVries-Seimon, M Ranalletta, CL Welch, ... Cell metabolism 3 (4), 257-266, 2006 | 319 | 2006 |
Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice JJ Manning-Tobin, KJ Moore, TA Seimon, SA Bell, M Sharuk, ... Arteriosclerosis, thrombosis, and vascular biology 29 (1), 19-26, 2009 | 300 | 2009 |
Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages TA Seimon, A Obstfeld, KJ Moore, DT Golenbock, I Tabas Proceedings of the National Academy of Sciences 103 (52), 19794-19799, 2006 | 229 | 2006 |
Zoonotic viruses associated with illegally imported wildlife products KM Smith, SJ Anthony, WM Switzer, JH Epstein, T Seimon, H Jia, ... PloS one 7 (1), e29505, 2012 | 221 | 2012 |
ABCA1 and ABCG1 protect against oxidative stress–induced macrophage apoptosis during efferocytosis L Yvan-Charvet, TA Pagler, TA Seimon, E Thorp, CL Welch, JL Witztum, ... Circulation research 106 (12), 1861-1869, 2010 | 217 | 2010 |
Gut microbiomes of wild great apes fluctuate seasonally in response to diet AL Hicks, KJ Lee, M Couto-Rodriguez, J Patel, R Sinha, C Guo, SH Olson, ... Nature communications 9 (1), 1786, 2018 | 214 | 2018 |
Macrophage deficiency of p38α MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice TA Seimon, Y Wang, S Han, T Senokuchi, DM Schrijvers, G Kuriakose, ... The Journal of clinical investigation 119 (4), 886-898, 2009 | 180 | 2009 |
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K Y Sun, M Ishibashi, T Seimon, M Lee, SM Sharma, KA Fitzgerald, ... Circulation research 104 (4), 455-465, 2009 | 166 | 2009 |
Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic … WS Lim, JM Timmins, TA Seimon, A Sadler, FD Kolodgie, R Virmani, ... Circulation 117 (7), 940-951, 2008 | 159 | 2008 |
IRE1β inhibits chylomicron production by selectively degrading MTP mRNA J Iqbal, K Dai, T Seimon, R Jungreis, M Oyadomari, G Kuriakose, D Ron, ... Cell metabolism 7 (5), 445-455, 2008 | 148 | 2008 |
Induction of ER stress in macrophages of tuberculosis granulomas TA Seimon, MJ Kim, A Blumenthal, J Koo, S Ehrt, H Wainwright, ... PloS one 5 (9), e12772, 2010 | 145 | 2010 |
Canine Distemper Virus: an Emerging Disease in Wild Endangered Amur Tigers (Panthera tigris altaica) TA Seimon, DG Miquelle, TY Chang, AL Newton, I Korotkova, G Ivanchuk, ... MBio 4 (4), 10.1128/mbio. 00410-13, 2013 | 140 | 2013 |
Macrophage apoptosis in advanced atherosclerosis I Tabas, T Seimon, J Timmins, G Li, W Lim Annals of the New York Academy of Sciences 1173, E40-E45, 2009 | 135 | 2009 |