Genome-scale CRISPR-mediated control of gene repression and activation LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ... Cell 159 (3), 647-661, 2014 | 2857 | 2014 |
A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ... Cell 167 (7), 1867-1882. e21, 2016 | 1026 | 2016 |
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ... Elife 5, e19760, 2016 | 772 | 2016 |
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells SJ Liu, MA Horlbeck, SW Cho, HS Birk, M Malatesta, D He, FJ Attenello, ... Science 355 (6320), eaah7111, 2017 | 744 | 2017 |
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 68 (1), 210-223. e6, 2017 | 231 | 2017 |
Next-generation libraries for robust RNA interference-based genome-wide screens M Kampmann, MA Horlbeck, Y Chen, JC Tsai, MC Bassik, LA Gilbert, ... Proceedings of the National Academy of Sciences 112 (26), E3384-E3391, 2015 | 108 | 2015 |