Programming cascade reactions interfacing biocatalysis with transition-metal catalysis in Deep Eutectic Solvents as biorenewable reaction media L Cicco, N Ríos-Lombardía, MJ Rodríguez-Álvarez, F Morís, FM Perna, ... Green Chemistry 20 (15), 3468-3475, 2018 | 106 | 2018 |
A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis LE Núñez, SE Nybo, J González-Sabín, M Pérez, N Menéndez, AF Braña, ... Journal of medicinal chemistry 55 (12), 5813-5825, 2012 | 92 | 2012 |
CAL-B-catalyzed resolution of some pharmacologically interesting β–substituted isopropylamines J González-Sabı́n, V Gotor, F Rebolledo Tetrahedron: Asymmetry 13 (12), 1315-1320, 2002 | 91 | 2002 |
Construction of chemoenzymatic cascade reactions for bridging chemocatalysis and Biocatalysis: Principles, strategies and prospective Y Liu, P Liu, S Gao, Z Wang, P Luan, J González-Sabín, Y Jiang Chemical Engineering Journal 420, 127659, 2021 | 90 | 2021 |
Asymmetric reduction of prochiral ketones by using self‐sufficient heterogeneous biocatalysts based on NADPH‐dependent ketoreductases AI Benítez‐Mateos, E San Sebastian, N Ríos‐Lombardía, F Morís, ... Chemistry–A European Journal 23 (66), 16843-16852, 2017 | 78 | 2017 |
Identification of mithramycin analogues with improved targeting of the EWS-FLI1 transcription factor CL Osgood, N Maloney, CG Kidd, S Kitchen-Goosen, L Segars, ... Clinical Cancer Research 22 (16), 4105-4118, 2016 | 76 | 2016 |
Regioselective enzymatic acylation of complex natural products: expanding molecular diversity J González-Sabín, R Morán-Ramallal, F Rebolledo Chemical Society Reviews 40 (11), 5321-5335, 2011 | 76 | 2011 |
From a sequential to a concurrent reaction in aqueous medium: ruthenium‐catalyzed allylic alcohol isomerization and asymmetric bioreduction N Ríos‐Lombardía, C Vidal, E Liardo, F Morís, J García‐Álvarez, ... Angewandte Chemie 128 (30), 8833-8837, 2016 | 66 | 2016 |
Elucidating the biosynthetic pathway for the polyketide-nonribosomal peptide collismycin A: mechanism for formation of the 2, 2′-bipyridyl ring I Garcia, NM Vior, AF Braña, J González-Sabin, J Rohr, F Moris, ... Chemistry & biology 19 (3), 399-413, 2012 | 58 | 2012 |
Chemoenzymatic Preparation of Optically Active trans‐Cyclohexane‐1,2‐diamine Derivatives: An Efficient Synthesis of the Analgesic U‐(−)‐50,488 J González‐Sabín, V Gotor, F Rebolledo Chemistry–A European Journal 10 (22), 5788-5794, 2004 | 55 | 2004 |
Chemoenzymatic one-pot synthesis in an aqueous medium: combination of metal-catalysed allylic alcohol isomerisation–asymmetric bioamination N Ríos-Lombardía, C Vidal, M Cocina, F Morís, J García-Álvarez, ... Chemical Communications 51 (54), 10937-10940, 2015 | 54 | 2015 |
One-pot combination of metal-and bio-catalysis in water for the synthesis of chiral molecules N Ríos-Lombardía, J García-Álvarez, J González-Sabín Catalysts 8 (2), 75, 2018 | 53 | 2018 |
Non‐conventional media as strategy to overcome the solvent dilemma in chemoenzymatic tandem catalysis R Kourist, J González‐Sabín ChemCatChem 12 (7), 1903-1912, 2020 | 51 | 2020 |
Enantioselective one-pot synthesis of biaryl-substituted amines by combining palladium and enzyme catalysis in deep eutectic solvents J Paris, A Telzerow, N Ríos-Lombardía, K Steiner, H Schwab, F Morís, ... ACS Sustainable Chemistry & Engineering 7 (5), 5486-5493, 2019 | 51 | 2019 |
Hybrid organo-and biocatalytic process for the asymmetric transformation of alcohols into amines in aqueous medium E Liardo, N Ríos-Lombardía, F Morís, F Rebolledo, J González-Sabín Acs Catalysis 7 (7), 4768-4774, 2017 | 51 | 2017 |
Kinetic resolution of (±)-trans-and (±)-cis-2-phenylcyclopentanamine by CALB-catalyzed aminolysis of esters: the key role of the leaving group J González-Sabı́n, V Gotor, F Rebolledo Tetrahedron: Asymmetry 15 (3), 481-488, 2004 | 51 | 2004 |
trans-Cyclopentane-1, 2-diamine: the second youth of the forgotten diamine J González-Sabín, F Rebolledo, V Gotor Chemical Society Reviews 38 (7), 1916-1925, 2009 | 50 | 2009 |
Using deep eutectic solvents to overcome limited substrate solubility in the enzymatic decarboxylation of bio-based phenolic acids AK Schweiger, N Ríos-Lombardía, CK Winkler, S Schmidt, F Morís, ... ACS Sustainable Chemistry & Engineering 7 (19), 16364-16370, 2019 | 49 | 2019 |
Combination of metal-catalyzed cycloisomerizations and biocatalysis in aqueous media: Asymmetric construction of chiral alcohols, lactones, and γ-hydroxy-carbonyl compounds MJ Rodriguez-Alvarez, N Rios-Lombardia, S Schumacher, ... ACS Catalysis 7 (11), 7753-7759, 2017 | 47 | 2017 |
Cycloalkane-1, 2-diamine derivatives as chiral solvating agents. Study of the structural variables controlling the NMR enantiodiscrimination of chiral carboxylic acids C Peña, J González-Sabín, I Alfonso, F Rebolledo, V Gotor Tetrahedron 64 (33), 7709-7717, 2008 | 46 | 2008 |