ARID1A deficiency impairs the DNA damage checkpoint and sensitizes cells to PARP inhibitors J Shen, Y Peng, L Wei, W Zhang, L Yang, L Lan, P Kapoor, Z Ju, Q Mo, ... Cancer discovery 5 (7), 752-767, 2015 | 444 | 2015 |
Spatial and temporal cellular responses to single-strand breaks in human cells S Okano, L Lan, KW Caldecott, T Mori, A Yasui Molecular and cellular biology, 2003 | 426 | 2003 |
In situ analysis of repair processes for oxidative DNA damage in mammalian cells L Lan, S Nakajima, Y Oohata, M Takao, S Okano, M Masutani, SH Wilson, ... Proceedings of the National Academy of Sciences 101 (38), 13738-13743, 2004 | 350 | 2004 |
Alternative lengthening of telomeres through two distinct break-induced replication pathways JM Zhang, T Yadav, J Ouyang, L Lan, L Zou Cell reports 26 (4), 955-968. e3, 2019 | 237 | 2019 |
MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A: T mutations in antibody genes TM Wilson, A Vaisman, SA Martomo, P Sullivan, L Lan, F Hanaoka, ... The Journal of experimental medicine 201 (4), 637-645, 2005 | 232 | 2005 |
Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining W Jiang, JL Crowe, X Liu, S Nakajima, Y Wang, C Li, BJ Lee, RL Dubois, ... Molecular cell 58 (1), 172-185, 2015 | 221 | 2015 |
The ACF1 complex is required for DNA double-strand break repair in human cells L Lan, A Ui, S Nakajima, K Hatakeyama, M Hoshi, R Watanabe, ... Molecular cell 40 (6), 976-987, 2010 | 220 | 2010 |
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway M Xing, M Yang, W Huo, F Feng, L Wei, W Jiang, S Ning, Z Yan, W Li, ... Nature communications 6 (1), 6233, 2015 | 182 | 2015 |
A novel human AP endonuclease with conserved zinc‐finger‐like motifs involved in DNA strand break responses S Kanno, H Kuzuoka, S Sasao, Z Hong, L Lan, S Nakajima, A Yasui The EMBO journal 26 (8), 2094-2103, 2007 | 175 | 2007 |
Vertebrate POLQ and POLβ cooperate in base excision repair of oxidative DNA damage M Yoshimura, M Kohzaki, J Nakamura, K Asagoshi, E Sonoda, E Hou, ... Molecular cell 24 (1), 115-125, 2006 | 174 | 2006 |
DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination L Wei, S Nakajima, S Böhm, KA Bernstein, Z Shen, M Tsang, AS Levine, ... Proceedings of the National Academy of Sciences 112 (27), E3495-E3504, 2015 | 164 | 2015 |
Accumulation of Werner protein at DNA double-strand breaks in human cells L Lan, S Nakajima, K Komatsu, A Nussenzweig, A Shimamoto, J Oshima, ... Journal of cell science 118 (18), 4153-4162, 2005 | 151 | 2005 |
ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB Y Teng, T Yadav, M Duan, J Tan, Y Xiang, B Gao, J Xu, Z Liang, Y Liu, ... Nature communications 9 (1), 4115, 2018 | 145 | 2018 |
Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids E Petermann, L Lan, L Zou Nature reviews Molecular cell biology 23 (8), 521-540, 2022 | 139 | 2022 |
Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis D Hu, M Gur, Z Zhou, A Gamper, MC Hung, N Fujita, L Lan, I Bahar, ... Nature communications 6 (1), 8419, 2015 | 137 | 2015 |
DNA polymerase λ protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair EK Braithwaite, PS Kedar, L Lan, YY Polosina, K Asagoshi, ... Journal of Biological Chemistry 280 (36), 31641-31647, 2005 | 129 | 2005 |
m5C modification of mRNA serves a DNA damage code to promote homologous recombination H Chen, H Yang, X Zhu, T Yadav, J Ouyang, SS Truesdell, J Tan, Y Wang, ... Nature communications 11 (1), 2834, 2020 | 119 | 2020 |
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β Q Fang, B Inanc, S Schamus, X Wang, L Wei, AR Brown, D Svilar, ... Nature communications 5 (1), 5513, 2014 | 117 | 2014 |
RNA transcripts stimulate homologous recombination by forming DR-loops J Ouyang, T Yadav, JM Zhang, H Yang, E Rheinbay, H Guo, DA Haber, ... Nature 594 (7862), 283-288, 2021 | 111 | 2021 |
Temporal relationship between hyperuricemia and insulin resistance and its impact on future risk of hypertension T Han, L Lan, R Qu, Q Xu, R Jiang, L Na, C Sun Hypertension 70 (4), 703-711, 2017 | 109 | 2017 |