The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts YP Shi, ZK Pang, R Venkateshappa, M Gunawan, J Kemp, E Truong, ... American Journal of Physiology-Heart and Circulatory Physiology 319 (2 …, 2020 | 21 | 2020 |
Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243 JM Kemp, DG Whittaker, R Venkateshappa, ZK Pang, R Johal, V Sergeev, ... Journal of General Physiology, 2021 | 14 | 2021 |
Utility of zebrafish models of acquired and inherited long QT syndrome KE Simpson, R Venkateshappa, ZK Pang, S Faizi, GF Tibbits, ... Frontiers in Physiology 11, 624129, 2021 | 9 | 2021 |
Ion channel model reduction using manifold boundaries DG Whittaker, J Wang, JG Shuttleworth, R Venkateshappa, JM Kemp, ... Journal of the Royal Society Interface 19 (193), 20220193, 2022 | 5 | 2022 |
Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/− long QT syndrome variant R Venkateshappa, DV Hunter, P Muralidharan, RS Nagalingam, G Huen, ... Cardiovascular Research 119 (15), 2522-2535, 2023 | 3 | 2023 |
CRISPR-Cas9-mediated Precise Knock-in Edits in Zebrafish Hearts KE Simpson, S Faizi, R Venkateshappa, M Yip, R Johal, D Poburko, ... JoVE (Journal of Visualized Experiments), e64209, 2022 | 1 | 2022 |
Development of an Absolute Quantification Method for hERG Using PRM with Single Isotopologue in-Sample Calibration G Chang, FA Aroge, R Venkateshappa, TW Claydon, B Sun ACS omega, 2024 | | 2024 |
Generation and characterization of induced pluripotent stem cells from breast cancer patients carrying ATM mutations M Zhang, R Venkateshappa, A Li, MB Fowler, ML Telli, JC Wu Stem cell research 73, 103246, 2023 | | 2023 |
Small molecule targeting of cardiac hERG channels to protect against arrhythmias' R Venkateshappa Simon Fraser University, 2023 | | 2023 |
Cannabidiol protects against lipopolysaccharides-induced inflammation in cardiac sodium channels M Fouda, YF Mohamed, R Venkateshappa, TW Claydon, R Fernandez, ... Biophysical Journal 121 (3), 92a-93a, 2022 | | 2022 |