Stabilization of i-motif structures by 2′-β-fluorination of DNA HA Assi, RW Harkness, N Martin-Pintado, CJ Wilds, R Campos-Olivas, ... Nucleic Acids Research 44 (11), 4998-5009, 2016 | 67 | 2016 |
G-quadruplex dynamics. RW Harkness, AK Mittermaier Biochimica et Biophysica acta. Proteins and Proteomics 1865 (11 Pt B), 1544-1554, 2017 | 60 | 2017 |
G-register exchange dynamics in guanine quadruplexes RW Harkness, AK Mittermaier Nucleic Acids Research 44 (8), 3481-3494, 2016 | 42 | 2016 |
Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR Y Toyama, RW Harkness, TYT Lee, JT Maynes, LE Kay Proceedings of the National Academy of Sciences 118 (11), e2025022118, 2021 | 34 | 2021 |
Mapping the energy landscapes of supramolecular assembly by thermal hysteresis RW Harkness, N Avakyan, HF Sleiman, AK Mittermaier Nature communications 9 (1), 3152, 2018 | 31 | 2018 |
Conformational dynamics of strand register shifts in DNA G-quadruplexes JT Grün, C Hennecker, DP Klötzner, RW Harkness, I Bessi, A Heckel, ... Journal of the American Chemical Society 142 (1), 264-273, 2019 | 26 | 2019 |
Rapid characterization of folding and binding interactions with thermolabile ligands by DSC RW Harkness, S Slavkovic, PE Johnson, AK Mittermaier Chemical Communications 52 (92), 13471-13474, 2016 | 18 | 2016 |
Correlating histone acetylation with nucleosome core particle dynamics and function TH Kim, ML Nosella, N Bolik-Coulon, RW Harkness, SK Huang, LE Kay Proceedings of the National Academy of Sciences 120 (15), e2301063120, 2023 | 15 | 2023 |
Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP RW Harkness, Y Toyama, ZA Ripstein, H Zhao, AIM Sever, Q Luan, ... Proceedings of the National Academy of Sciences 118 (32), e2109732118, 2021 | 15 | 2021 |
Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein Y Toyama, RW Harkness, LE Kay Proceedings of the National Academy of Sciences 118 (35), e2111257118, 2021 | 13 | 2021 |
Parallel reaction pathways accelerate folding of a guanine quadruplex RW Harkness, C Hennecker, JT Grün, A Blümler, A Heckel, H Schwalbe, ... Nucleic acids research 49 (3), 1247-1262, 2021 | 13 | 2021 |
Less is more: A simple methyl-TROSY based pulse scheme offers improved sensitivity in applications to high molecular weight complexes N Bolik-Coulon, AIM Sever, RW Harkness, JM Aramini, Y Toyama, ... Journal of Magnetic Resonance 346, 107326, 2023 | 12 | 2023 |
Poly (ADP-ribosyl) ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates ML Nosella, TH Kim, SK Huang, RW Harkness, M Goncalves, A Pan, ... Molecular Cell 84 (3), 429-446. e17, 2024 | 9 | 2024 |
Structural basis of protein substrate processing by human mitochondrial high-temperature requirement A2 protease Y Toyama, RW Harkness, LE Kay Proceedings of the National Academy of Sciences 119 (17), e2203172119, 2022 | 9 | 2022 |
Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations A Parupudi, SK Chaturvedi, R Adão, RW Harkness, S Dragulin-Otto, ... Scientific Reports 11 (1), 5741, 2021 | 7 | 2021 |
Analyzing multi-step ligand binding reactions for oligomeric proteins by NMR: Theoretical and computational considerations RW Harkness, Y Toyama, LE Kay Journal of Magnetic Resonance 318, 106802, 2020 | 6 | 2020 |
Experimental and computational determination of Brønsted coefficients for equilibrium transfer of the O,O‐dimethyl phosphorothioyl group between oxyanion … DR Edwards, CI Maxwell, RW Harkness, AA Neverov, NJ Mosey, ... Journal of Physical Organic Chemistry 25 (3), 258-266, 2012 | 5 | 2012 |
Flexible client-dependent cages in the assembly landscape of the periplasmic protease-chaperone DegP RW Harkness, ZA Ripstein, JM Di Trani, LE Kay Journal of the American Chemical Society 145 (24), 13015-13026, 2023 | 4 | 2023 |
Measuring Biomolecular DSC Profiles with Thermolabile Ligands to Rapidly Characterize Folding and Binding Interactions RW Harkness, PE Johnson, AK Mittermaier JoVE (Journal of Visualized Experiments), e55959, 2017 | 2 | 2017 |
Activation of caspase-9 on the apoptosome as studied by methyl-TROSY NMR AIM Sever, TR Alderson, E Rennella, JM Aramini, ZH Liu, RW Harkness, ... Proceedings of the National Academy of Sciences 120 (51), e2310944120, 2023 | 1 | 2023 |