Reduced lipid bilayer thickness regulates the aggregation and cytotoxicity of amyloid-β KJ Korshavn, C Satriano, Y Lin, R Zhang, M Dulchavsky, A Bhunia, ... Journal of Biological Chemistry 292 (11), 4638-4650, 2017 | 167 | 2017 |
Proteostasis of Islet Amyloid Polypeptide: a Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes D Milardi, E Gazit, SE Radford, Y Xu, RU Gallardo, A Caflisch, ... Chemical Reviews 121 (3), 1845-1893, 2021 | 153 | 2021 |
Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Aβ and hIAPP MFM Sciacca, C Tempra, F Scollo, D Milardi, C La Rosa Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1625-1638, 2018 | 131 | 2018 |
Lipid-chaperone hypothesis: A common molecular mechanism of membrane disruption by intrinsically disordered proteins MF Sciacca, F Lolicato, C Tempra, F Scollo, BR Sahoo, MD Watson, ... ACS chemical neuroscience 11 (24), 4336-4350, 2020 | 125 | 2020 |
Cations as Switches of Amyloid-Mediated Membrane Disruption Mechanisms: Calcium and IAPP MFM Sciacca, D Milardi, GML Messina, G Marletta, JR Brender, ... Biophysical Journal 104 (1), 173-184, 2013 | 120 | 2013 |
α-helical structures drive early stages of self-assembly of amyloidogenic amyloid polypeptide aggregate formation in membranes M Pannuzzo, A Raudino, D Milardi, C La Rosa, M Karttunen Scientific reports 3 (1), 2781, 2013 | 107 | 2013 |
Probing the sources of the apparent irreproducibility of amyloid formation: drastic changes in kinetics and a switch in mechanism due to micellelike oligomer formation at … JR Brender, J Krishnamoorthy, MFM Sciacca, S Vivekanandan, L D’Urso, ... The journal of physical chemistry B 119 (7), 2886-2896, 2015 | 100 | 2015 |
Thermodynamics of the thermal unfolding of azurin C La Rosa, D Milardi, D Grasso, R Guzzi, L Sportelli The Journal of Physical Chemistry 99 (40), 14864-14870, 1995 | 100 | 1995 |
The role of cholesterol in driving IAPP-membrane interactions MFM Sciacca, F Lolicato, G Di Mauro, D Milardi, L D’Urso, C Satriano, ... Biophysical journal 111 (1), 140-151, 2016 | 93 | 2016 |
Inhibition of Aβ amyloid growth and toxicity by silybins: The crucial role of stereochemistry MFM Sciacca, V Romanucci, A Zarrelli, I Monaco, F Lolicato, N Spinella, ... ACS chemical neuroscience 8 (8), 1767-1778, 2017 | 85 | 2017 |
Phospholipids critical micellar concentrations trigger different mechanisms of intrinsically disordered proteins interaction with model membranes F Scollo, C Tempra, F Lolicato, MFM Sciacca, A Raudino, D Milardi, ... The journal of physical chemistry letters 9 (17), 5125-5129, 2018 | 80 | 2018 |
Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide JR Brender, J Krishnamoorthy, GML Messina, A Deb, S Vivekanandan, ... Chemical Communications 49 (32), 3339-3341, 2013 | 75 | 2013 |
Extended theoretical analysis of irreversible protein thermal unfolding D Milardi, C La Rosa, D Grasso Biophysical chemistry 52 (3), 183-189, 1994 | 69 | 1994 |
A spectroscopic and calorimetric investigation on the thermal stability of the Cys3Ala/Cys26Ala azurin mutant R Guzzi, L Sportelli, C La Rosa, D Milardi, D Grasso, MP Verbeet, ... Biophysical journal 77 (2), 1052-1063, 1999 | 62 | 1999 |
The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH D Milardi, MFM Sciacca, M Pappalardo, DM Grasso, C La Rosa European Biophysics Journal 40, 1-12, 2011 | 57 | 2011 |
Analytical model and multiscale simulations of Aβ peptide aggregation in lipid membranes: towards a unifying description of conformational transitions, oligomerization and … M Pannuzzo, D Milardi, A Raudino, M Karttunen, C La Rosa Physical Chemistry Chemical Physics 15 (23), 8940-8951, 2013 | 55 | 2013 |
Lipid-assisted protein transport: A diffusion-reaction model supported by kinetic experiments and molecular dynamics simulations C La Rosa, S Scalisi, F Lolicato, M Pannuzzo, A Raudino The Journal of chemical physics 144 (18), 2016 | 52 | 2016 |
Resveratrol interferes with the aggregation of membrane-bound human-IAPP: A molecular dynamics study F Lolicato, A Raudino, D Milardi, C La Rosa European journal of medicinal chemistry 92, 876-881, 2015 | 50 | 2015 |
Thermodynamics and kinetics of the thermal unfolding of plastocyanin D Milardi, C La Rosa, D Grasso, R Guzzi, L Sportelli, C Fini European biophysics journal 27, 273-282, 1998 | 47 | 1998 |
Thermal expansion and compressibility coefficients of phospholipid vesicles: experimental determination and theoretical modeling A Raudino, F Zuccarello, C La Rosa, G Buemi Journal of Physical Chemistry 94 (10), 4217-4223, 1990 | 46 | 1990 |