Cellular stress responses in radiotherapy W Kim, S Lee, D Seo, D Kim, K Kim, EG Kim, JH Kang, KM Seong, ... Cells 8 (9), 1105, 2019 | 291 | 2019 |
The role of tumor microenvironment in therapeutic resistance B Son, S Lee, HS Youn, EG Kim, W Kim, BH Youn Oncotarget 8 (3), 3933, 2017 | 288 | 2017 |
Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small … JH Kang, EG Kim, W Kim, KM Seong, HS Youn, JW Kim, J Kim, BH Youn Journal of Biological Chemistry 288 (38), 27343-27357, 2013 | 203 | 2013 |
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ... The Journal of Clinical Investigation 130 (2), 981-997, 2020 | 196 | 2020 |
PAK1 tyrosine phosphorylation is required to induce epithelial–mesenchymal transition and radioresistance in lung cancer cells EG Kim, HS Youn, TW Kwon, B Son, JH Kang, HJ Yang, KM Seong, ... Cancer research 74 (19), 5520-5531, 2014 | 91 | 2014 |
TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial–mesenchymal transition W Kim, EG Kim, S Lee, D Kim, J Chun, KH Park, HS Youn, BH Youn Experimental & molecular medicine 48 (11), e273-e273, 2016 | 73 | 2016 |
TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183-and miR-33a-mediated cell cycle regulation J Kang, W Kim, S Lee, D Kwon, J Chun, B Son, E Kim, JM Lee, H Youn, ... Oncogene 36 (11), 1585-1596, 2017 | 71 | 2017 |
PIM1 kinase inhibitors induce radiosensitization in non-small cell lung cancer cells W Kim, HS Youn, TW Kwon, JH Kang, EG Kim, B Son, HJ Yang, Y Jung, ... Pharmacological research 70 (1), 90-101, 2013 | 57 | 2013 |
RNF138-mediated ubiquitination of rpS3 is required for resistance of glioblastoma cells to radiation-induced apoptosis W Kim, HS Youn, S Lee, EG Kim, D Kim, JS Lee, JM Lee, BH Youn Experimental & molecular medicine 50 (1), e434-e434, 2018 | 53 | 2018 |
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain S Shukla, W Ying, F Gray, Y Yao, ML Simes, Q Zhao, H Miao, HJ Cho, ... Nature Chemical Biology, 1-10, 2021 | 50 | 2021 |
TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts EG Kim, W Kim, S Lee, J Chun, JH Kang, G Park, IJ Han, HJ Yang, ... Scientific reports 7 (1), 1-14, 2017 | 45 | 2017 |
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity DS Rogawski, J Deng, H Li, H Miao, D Borkin, T Purohit, J Song, J Chase, ... Nature Communications 12 (1), 1-14, 2021 | 37 | 2021 |
GAS41 recognizes diacetylated histone H3 through a bivalent binding mode HJ Cho, H Li, BM Linhares, EG Kim, J Ndoj, H Miao, J Grembecka, ... ACS chemical biology 13 (9), 2739-2746, 2018 | 37 | 2018 |
Surfactant protein B suppresses lung cancer progression by inhibiting secretory phospholipase A2 activity and arachidonic acid production S Lee, D Kim, JH Kang, E Kim, W Kim, HS Youn, BH Youn Cellular Physiology and Biochemistry 42 (4), 1684-1700, 2017 | 33 | 2017 |
Radiation-induced overexpression of transthyretin inhibits retinol-mediated hippocampal neurogenesis JH Kang, W Kim, HJ Seo, EG Kim, B Son, S Lee, G Park, S Jo, C Moon, ... Scientific reports 8 (1), 1-14, 2018 | 32 | 2018 |
Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML with activating FLT3 mutations H Miao, EG Kim, D Chen, T Purohit, K Kempinska, J Ropa, S Klossowski, ... Blood, 2020 | 29 | 2020 |
Inhibition of hedgehog signalling attenuates UVB‐induced skin photoageing W Kim, EG Kim, HJ Yang, TW Kwon, SY Han, S Lee, HS Youn, Y Jung, ... Experimental dermatology 24 (8), 611-617, 2015 | 24 | 2015 |
Development of potent dimeric inhibitors of GAS41 YEATS domain D Listunov, BM Linhares, EG Kim, A Winkler, ML Simes, S Weaver, ... Cell Chemical Biology, 2021 | 21 | 2021 |
Ash1l inhibitors and methods of treatment therewith J Grembecka, S Klossowski, J Deng, T Cierpicki, H Li, H Miao, T Purohit, ... US Patent App. 16/186,018, 2019 | 5 | 2019 |
Ash1l degraders and methods of treatment therewith J Grembecka, S Klossowski, J Deng, T Cierpicki, H Li, H Miao, T Purohit, ... US Patent App. 16/186,012, 2019 | 5 | 2019 |