| Prolinks: a database of protein functional linkages derived from coevolution PM Bowers, M Pellegrini, MJ Thompson, J Fierro, TO Yeates, D Eisenberg Genome biology 5, 1-13, 2004 | 384 | 2004 |
| De novo protein structure determination using sparse NMR data PM Bowers, CEM Strauss, D Baker Journal of biomolecular NMR 18, 311-318, 2000 | 230 | 2000 |
| Use of logic relationships to decipher protein network organization PM Bowers, SJ Cokus, D Eisenberg, TO Yeates Science 306 (5705), 2246-2249, 2004 | 190 | 2004 |
| Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies PM Bowers, RA Horlick, TY Neben, RM Toobian, GL Tomlinson, JL Dalton, ... Proceedings of the National Academy of Sciences 108 (51), 20455-20460, 2011 | 136 | 2011 |
| Mammalian cell display for the discovery and optimization of antibody therapeutics PM Bowers, RA Horlick, MR Kehry, TY Neben, GL Tomlinson, L Altobell, ... Methods 65 (1), 44-56, 2014 | 87 | 2014 |
| An integrated approach to extreme thermostabilization and affinity maturation of an antibody AD McConnell, V Spasojevich, JL Macomber, IP Krapf, A Chen, ... Protein Engineering, Design & Selection 26 (2), 151-164, 2013 | 79 | 2013 |
| Methods of generating libraries and uses thereof PM Bowers, AB Cubitt, RA Horlick US Patent 8,603,950, 2013 | 69 | 2013 |
| A general approach to antibody thermostabilization AD McConnell, X Zhang, JL Macomber, B Chau, JC Sheffer, ... MAbs 6 (5), 1274-1282, 2014 | 57 | 2014 |
| A folding transition and novel zinc finger accessory domain in the transcription factor ADR1 PM Bowers, LE Schaufler, RE Klevit Nature structural biology 6 (5), 478-485, 1999 | 55 | 1999 |
| Utilizing logical relationships in genomic data to decipher cellular processes PM Bowers, BD O'Connor, SJ Cokus, E Sprinzak, TO Yeates, D Eisenberg The FEBS journal 272 (20), 5110-5118, 2005 | 49 | 2005 |
| Hydrogen bonding and equilibrium isotope enrichment in histidine-containing proteins PM Bowers, RE Klevit Nature Structural Biology 3 (6), 522-531, 1996 | 45 | 1996 |
| Simultaneous surface display and secretion of proteins from mammalian cells facilitate efficient in vitro selection and maturation of antibodies RA Horlick, JL Macomber, PM Bowers, TY Neben, GL Tomlinson, IP Krapf, ... Journal of biological chemistry 288 (27), 19861-19869, 2013 | 44 | 2013 |
| The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function CW Goulding, PM Bowers, B Segelke, T Lekin, CY Kim, TC Terwilliger, ... Journal of molecular biology 365 (2), 275-283, 2007 | 42 | 2007 |
| High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation AD McConnell, M Do, TY Neben, V Spasojevic, J MacLaren, AP Chen, ... PLoS One 7 (11), e49458, 2012 | 35 | 2012 |
| Use of somatic hypermutation to create insertion and deletion mutations in vitro DJ King, P Bowers, RA Horlick US Patent App. 13/655,793, 2013 | 33 | 2013 |
| Methods of generating libraries and uses thereof PM Bowers, AB Cubitt, RA Horlick US Patent 8,685,897, 2014 | 32 | 2014 |
| Computational method to assign microbial genes to pathways M Pellegrini, M Thompson, J Fierro, P Bowers Journal of Cellular Biochemistry 84 (S37), 106-109, 2001 | 32 | 2001 |
| Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies PM Bowers, P Verdino, Z Wang, J da Silva Correia, M Chhoa, ... Journal of Biological Chemistry 289 (48), 33557-33567, 2014 | 29 | 2014 |
| Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation PM Bowers, TY Neben, GL Tomlinson, JL Dalton, L Altobell, X Zhang, ... Journal of Biological Chemistry 288 (11), 7688-7696, 2013 | 25 | 2013 |
| Humanized antibodies directed against complement protein C5 A Mcconnell, PM Bowers, DJ King US Patent 9,133,269, 2015 | 24 | 2015 |
