Hypoxia regulates the degradation of non-nuclear organelles during lens differentiation through activation of HIF1a L Brennan, J Disatham, M Kantorow Experimental eye research 198, 108129, 2020 | 30 | 2020 |
Mechanisms of organelle elimination for lens development and differentiation L Brennan, J Disatham, M Kantorow Experimental eye research 209, 108682, 2021 | 29 | 2021 |
Lens differentiation is characterized by stage-specific changes in chromatin accessibility correlating with differentiation state-specific gene expression J Disatham, D Chauss, R Gheyas, L Brennan, D Blanco, L Daley, ... Developmental biology 453 (1), 86-104, 2019 | 17 | 2019 |
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation J Disatham, L Brennan, X Jiao, Z Ma, JF Hejtmancik, M Kantorow Epigenetics & Chromatin 15 (1), 8, 2022 | 14 | 2022 |
A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis J Disatham, L Brennan, D Chauss, J Kantorow, B Afzali, M Kantorow BMC genomics 22, 1-20, 2021 | 8 | 2021 |
Multiomics analysis reveals novel genetic determinants for lens differentiation, structure, and transparency J Disatham, L Brennan, A Cvekl, M Kantorow Biomolecules 13 (4), 693, 2023 | 3 | 2023 |
Patterns of crystallin gene expression in differentiation state specific regions of the embryonic chicken lens Z Ma, D Chauss, J Disatham, X Jiao, LA Brennan, AS Menko, M Kantorow, ... Investigative ophthalmology & visual science 63 (4), 8-8, 2022 | 3 | 2022 |
Hypoxia-regulated epigenetic programing governs lens fiber cell differentiation LA Brennan, J Disatham, M Kantorow Investigative Ophthalmology & Visual Science 65 (7), 1476-1476, 2024 | | 2024 |
Multiomic analysis implicates FOXO4 in genetic regulation of chick lens fiber cell differentiation L Brennan, J Disatham, AS Menko, M Kantorow Developmental Biology 504, 25-37, 2023 | | 2023 |
Epigenetic programming regulates lens fiber cell gene expression to achieve lens fiber cell form and function and is dependent on the hypoxic environment of differentiating … LA Brennan, J Disatham, M Kantorow Investigative Ophthalmology & Visual Science 64 (8), 4395-4395, 2023 | | 2023 |
Multiomic analysis of HIF1a binding, regulation and gene expression combined with characterization of novel lens conditional HIF1a KO mice reveals essential requirements for … J Disatham, LA Brennan, ML Robinson, M Kantorow Investigative Ophthalmology & Visual Science 64 (8), 522-522, 2023 | | 2023 |
Gene Silencing by DNA Methylation Predicts Chromatin Regions and Transcription Factors Required for Lens Differentiation J Disatham, LA Brennan, X Jiao, Z Ma, JF Hejtmancik, M Kantorow Investigative Ophthalmology & Visual Science 63 (7), 838-838, 2022 | | 2022 |
Hypoxia and Chromatin Remodeling: Essential Regulators of Ocular Lens Cell Differentiation J Disatham Florida Atlantic University, 2022 | | 2022 |
Multiomic identification of genome-wide DNA binding sites and target genes identifies HIF1α as a hypoxia-dependent master regulator of lens gene expression J Disatham, LA Brennan, D Chauss, J Kantorow, B Afzali, M Kantorow Investigative Ophthalmology & Visual Science 62 (8), 2081-2081, 2021 | | 2021 |
Hypoxia regulates lens fiber cell differentiation to form the mature transparent eye lens LA Brennan, J Disatham, M Kantorow Investigative Ophthalmology & Visual Science 61 (7), 2300-2300, 2020 | | 2020 |
Genome-wide chromatin mapping and transcriptome analysis reveals chromatin regulation as a novel mechanism for controlling gene expression during lens differentiation J Disatham, D Chauss, R Gheyas, LA Brennan, D Blanco, L Daley, ... Investigative Ophthalmology & Visual Science 60 (9), 4286-4286, 2019 | | 2019 |
Let us know how access to this document benefits you. Z Ma, D Chauss, J Disatham, X Jiao, LA Brennan | | 2016 |