关注
Hsueh-Yuan Chang
Hsueh-Yuan Chang
其他姓名HY Chang
Senior Clinical Pharmacologist at Takeda Development Center Americas INC
在 buffalo.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Intervertebral disc regeneration in an ex vivo culture system using mesenchymal stem cells and platelet-rich plasma
WH Chen, HY Liu, WC Lo, SC Wu, CH Chi, HY Chang, SH Hsiao, CH Wu, ...
Biomaterials 30 (29), 5523-5533, 2009
1762009
Antibody pharmacokinetics in rat brain determined using microdialysis
HY Chang, K Morrow, E Bonacquisti, WY Zhang, DK Shah
MAbs 10 (6), 843-853, 2018
722018
A translational platform PBPK model for antibody disposition in the brain
HY Chang, S Wu, G Meno-Tetang, DK Shah
Journal of pharmacokinetics and pharmacodynamics 46, 319-338, 2019
632019
Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models
EA Chowdhury, G Meno-Tetang, HY Chang, S Wu, HW Huang, T Jamier, ...
Advanced Drug Delivery Reviews 170, 214-237, 2021
532021
Effect of size on solid tumor disposition of protein therapeutics
Z Li, Y Li, HP Chang, HY Chang, L Guo, DK Shah
Drug Metabolism and Disposition 47 (10), 1136-1145, 2019
422019
Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis
HY Chang, S Wu, Y Li, W Zhang, M Burrell, CI Webster, DK Shah
MAbs 13 (1), 1874121, 2021
332021
Effect of the size of protein therapeutics on brain pharmacokinetics following systematic administration
HY Chang, S Wu, Y Li, L Guo, Y Li, DK Shah
The AAPS journal 24 (3), 62, 2022
132022
Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central …
HY Chang, S Wu, EA Chowdhury, DK Shah
Journal of Pharmacokinetics and Pharmacodynamics 49 (3), 337-362, 2022
82022
Pharmacokinetics of monoclonal antibody and antibody fragments in the mouse eye following systemic administration
D Bussing, Z Li, Y Li, HP Chang, HY Chang, L Guo, A Verma, DK Shah
The AAPS Journal 23, 1-11, 2021
42021
Investigation of Antibody Pharmacokinetics in the Brain Following Intra-CNS Administration and Development of PBPK Model to Characterize the Data
S Wu, HY Chang, EA Chowdhury, HW Huang, DK Shah
The AAPS Journal 26 (2), 29, 2024
2024
Approaches towards prediction of CNS PK and PD
ECM Lange, HY Chang, D Shah
Drug Delivery to the Brain: Physiological Concepts, Methodologies and …, 2022
2022
Quantitative Investigation of Pharmacokinetics of Antibody-Based Therapeutics in the Central Nervous System
HY Chang
State University of New York at Buffalo, 2021
2021
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