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Vancheswaran Gopalakrishnan
Vancheswaran Gopalakrishnan
在 astrazeneca.com 的电子邮件经过验证
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引用次数
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Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
V Gopalakrishnan, CN Spencer, L Nezi, A Reuben, MC Andrews, ...
Science 359 (6371), 97-103, 2018
40362018
B cells and tertiary lymphoid structures promote immunotherapy response
BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ...
Nature 577 (7791), 549-555, 2020
18142020
Defining T cell states associated with response to checkpoint immunotherapy in melanoma
M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ...
Cell 175 (4), 998-1013. e20, 2018
14812018
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
D Nejman, I Livyatan, G Fuks, N Gavert, Y Zwang, LT Geller, ...
Science 368 (6494), 973-980, 2020
14652020
Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
LT Geller, M Barzily-Rokni, T Danino, OH Jonas, N Shental, D Nejman, ...
Science 357 (6356), 1156-1160, 2017
13892017
The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy
V Gopalakrishnan, BA Helmink, CN Spencer, A Reuben, JA Wargo
Cancer cell 33 (4), 570-580, 2018
11822018
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade
PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ...
Cancer discovery 6 (8), 827-837, 2016
9582016
The microbiome, cancer, and cancer therapy
BA Helmink, MAW Khan, A Hermann, V Gopalakrishnan, JA Wargo
Nature medicine 25 (3), 377-388, 2019
9422019
Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance
W Roh, PL Chen, A Reuben, CN Spencer, PA Prieto, JP Miller, ...
Science translational medicine 9 (379), eaah3560, 2017
7732017
Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma
RN Amaria, SM Reddy, HA Tawbi, MA Davies, MI Ross, IC Glitza, ...
Nature medicine 24 (11), 1649-1654, 2018
7352018
Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis
Y Wang, DH Wiesnoski, BA Helmink, V Gopalakrishnan, K Choi, ...
Nature medicine 24 (12), 1804-1808, 2018
6052018
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response
CN Spencer, JL McQuade, V Gopalakrishnan, JA McCulloch, M Vetizou, ...
Science 374 (6575), 1632-1640, 2021
4792021
The gut microbiota influences anticancer immunosurveillance and general health
B Routy, V Gopalakrishnan, R Daillère, L Zitvogel, JA Wargo, G Kroemer
Nature Reviews Clinical Oncology 15 (6), 382-396, 2018
4442018
Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised …
RN Amaria, PA Prieto, MT Tetzlaff, A Reuben, MC Andrews, MI Ross, ...
The Lancet Oncology 19 (2), 181-193, 2018
2812018
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
MC Andrews, CPM Duong, V Gopalakrishnan, V Iebba, WS Chen, ...
Nature medicine 27 (8), 1432-1441, 2021
2752021
Defining T cell states associated with response to checkpoint immunotherapy in melanoma
M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ...
Cell 176 (1), 404, 2019
2182019
Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade
N Jacquelot, T Yamazaki, MP Roberti, CPM Duong, MC Andrews, ...
Cell research 29 (10), 846-861, 2019
2032019
TCR repertoire intratumor heterogeneity in localized lung adenocarcinomas: an association with predicted neoantigen heterogeneity and postsurgical recurrence
A Reuben, R Gittelman, J Gao, J Zhang, EC Yusko, CJ Wu, R Emerson, ...
Cancer discovery 7 (10), 1088-1097, 2017
1832017
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma
A Reuben, CN Spencer, PA Prieto, V Gopalakrishnan, SM Reddy, ...
NPJ genomic medicine 2 (1), 10, 2017
1322017
Poor response to neoadjuvant chemotherapy correlates with mast cell infiltration in inflammatory breast cancer
SM Reddy, A Reuben, S Barua, H Jiang, S Zhang, L Wang, ...
Cancer immunology research 7 (6), 1025-1035, 2019
892019
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