A novel assay for RNA polymerase I transcription elongation sheds light on the evolutionary divergence of eukaryotic RNA polymerases CE Scull, ZM Ingram, AL Lucius, DA Schneider Biochemistry 58 (16), 2116-2124, 2019 | 30 | 2019 |
Defining the divergent enzymatic properties of RNA polymerases I and II RQ Jacobs, ZM Ingram, AL Lucius, DA Schneider Journal of Biological Chemistry 296, 2021 | 27 | 2021 |
Multi-start Evolutionary Nonlinear OpTimizeR (MENOTR): A hybrid parameter optimization toolbox ZM Ingram, NW Scull, DS Schneider, AL Lucius Biophysical chemistry 279, 106682, 2021 | 22 | 2021 |
RNA polymerase I is uniquely vulnerable to the small-molecule inhibitor BMH-21 RQ Jacobs, KB Fuller, SL Cooper, ZI Carter, M Laiho, AL Lucius, ... Cancers 14 (22), 5544, 2022 | 15 | 2022 |
Transient-state kinetic analysis of the RNA polymerase II nucleotide incorporation mechanism ZI Carter, RQ Jacobs, DA Schneider, AL Lucius Biochemistry 62 (1), 95-108, 2022 | 13 | 2022 |
Transient-state kinetic analysis of multi-nucleotide addition catalyzed by RNA polymerase I ZM Ingram, DA Schneider, AL Lucius Biophysical Journal 120 (20), 4378-4390, 2021 | 11 | 2021 |
Uncovering the mechanisms of transcription elongation by eukaryotic RNA polymerases I, II, and III RQ Jacobs, ZI Carter, AL Lucius, DA Schneider Iscience 25 (11), 2022 | 9 | 2022 |
The cofactor-dependent folding mechanism of Drosophila cryptochrome revealed by single-molecule pulling experiments S Foroutannejad, LL Good, C Lin, ZI Carter, MG Tadesse, AL Lucius, ... Nature Communications 14 (1), 1057, 2023 | 3 | 2023 |
Uncovering the unique biophysical properties of RNA polymerases I, II, and III RQ Jacobs, ZM Ingram, AL Lucius, DA Schneider Biophysical Journal 121 (3), 33a-34a, 2022 | 1 | 2022 |
Platform for measuring polymerase nucleotide misincorporation kinetics reveals mechanistic differences between wild-type and engineered RNAPs ZI Carter, WB O'Brien, AF Gardner Biophysical Journal 123 (3), 222a, 2024 | | 2024 |
High-throughput Kinetics using Capillary Electrophoresis and Robotics (HiKER) platform used to Study T7, T3, and Sp6 RNA Polymerase Misincorporation AF Gardner, ZI Carter, SR Lund, W O'Brien bioRxiv, 2024.03. 20.585964, 2024 | | 2024 |
Global Kinetic Mechanism Describing Single Nucleotide Incorporation for RNA Polymerase I Reveals Fast UMP Incorporation KB Fuller, RQ Jacobs, ZG Cuny, DA Schneider, A Lucius, ZI Carter Available at SSRN 4747029, 2024 | | 2024 |
Unique Biochemical Properties of Eukaryotic RNA polymerases I, II, and III RQ Jacobs, ZM Ingram, AL Lucius, DA Schneider The FASEB Journal 36, 2022 | | 2022 |
The cofactor-dependent folding energy landscape of a light-sensing protein revealed by single-molecule pulling experiments R Maillard, S Foroutannejad, L Good, C Lin, Z Ingram, M Tadesse, ... | | 2022 |
Single-molecule dissection of coupling mechanisms between cofactor binding and folding of a complex protein S Foroutannejad, L Good, C Manahan, Z Ingram, C Lin, M Tadesse, ... Biophysical Journal 121 (3), 186a, 2022 | | 2022 |
Kinetic Mechanism Investigations of Nucleotide Addition Catalyzed by RNA Polymerase I and II ZM Ingram The University of Alabama at Birmingham, 2021 | | 2021 |
Deciphering Kinetics of RNA Polymerase I Multi-Nucleotide Transcription Z Ingram, DA Schneider, AL Lucius Biophysical Journal 118 (3), 543a, 2020 | | 2020 |
Mutation of the RNA polymerase I trigger loop reveals functional divergence of the eukaryotic RNA polymerases. CE Scull, ZM Ingram, AL Lucius, DA Schneider MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |