| Takinib, a selective TAK1 inhibitor, broadens the therapeutic efficacy of TNF-α inhibition for cancer and autoimmune disease J Totzke, D Gurbani, R Raphemot, PF Hughes, K Bodoor, DA Carlson, ... Cell chemical biology 24 (8), 1029-1039. e7, 2017 | 135 | 2017 |
| Eliciting renal failure in mosquitoes with a small-molecule inhibitor of inward-rectifying potassium channels R Raphemot, MF Rouhier, CR Hopkins, RD Gogliotti, KM Lovell, RM Hine, ... PloS one 8 (5), e64905, 2013 | 78 | 2013 |
| Discovery, characterization, and structure–activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2. 3, Kir3. x, and Kir7. 1 R Raphemot, DF Lonergan, TT Nguyen, T Utley, LM Lewis, R Kadakia, ... Frontiers in pharmacology 2, 75, 2011 | 58 | 2011 |
| Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels R Raphemot, MF Rouhier, DR Swale, E Days, CD Weaver, KM Lovell, ... PloS one 9 (11), e110772, 2014 | 55 | 2014 |
| Localization and role of inward rectifier K+ channels in Malpighian tubules of the yellow fever mosquito Aedes aegypti PM Piermarini, SM Dunemann, MF Rouhier, TL Calkins, R Raphemot, ... Insect biochemistry and molecular biology 67, 59-73, 2015 | 43 | 2015 |
| Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti MF Rouhier, R Raphemot, JS Denton, PM Piermarini PloS one 9 (6), e100700, 2014 | 42 | 2014 |
| Direct activation of β-cell KATP channels with a novel xanthine derivative R Raphemot, DR Swale, PK Dadi, DA Jacobson, P Cooper, AP Wojtovich, ... Molecular pharmacology 85 (6), 858-865, 2014 | 41 | 2014 |
| Current therapies and future possibilities for drug development against liver-stage malaria R Raphemot, D Posfai, ER Derbyshire The Journal of clinical investigation 126 (6), 2013-2020, 2016 | 40 | 2016 |
| Discovery of druggable host factors critical to Plasmodium liver-stage infection R Raphemot, M Toro-Moreno, KY Lu, D Posfai, ER Derbyshire Cell chemical biology 26 (9), 1253-1262. e5, 2019 | 34 | 2019 |
| Molecular and functional characterization of Anopheles gambiae inward rectifier potassium (Kir1) channels: a novel role in egg production R Raphemot, TY Estévez-Lao, MF Rouhier, PM Piermarini, JS Denton, ... Insect biochemistry and molecular biology 51, 10-19, 2014 | 34 | 2014 |
| Discovery of dual-stage malaria inhibitors with new targets R Raphemot, MJ Lafuente-Monasterio, FJ Gamo-Benito, J Clardy, ... Antimicrobial agents and chemotherapy 60 (3), 1430-1437, 2016 | 33 | 2016 |
| Development and validation of fluorescence-based and automated patch clamp–based functional assays for the inward rectifier potassium channel kir4. 1 R Raphemot, RJ Kadakia, ML Olsen, S Banerjee, E Days, SS Smith, ... ASSAY and Drug Development Technologies 11 (9-10), 532-543, 2013 | 33 | 2013 |
| ML418: The first selective, sub-micromolar pore blocker of Kir7. 1 potassium channels DR Swale, H Kurata, SV Kharade, J Sheehan, R Raphemot, KR Voigtritter, ... ACS chemical neuroscience 7 (7), 1013-1023, 2016 | 28 | 2016 |
| High-throughput screening for small-molecule modulators of inward rectifier potassium channels R Raphemot, CD Weaver, JS Denton Journal of visualized experiments: JoVE, 2013 | 26 | 2013 |
| Excretion of NaCl and KCl loads in mosquitoes. 2. Effects of the small molecule Kir channel modulator VU573 and its inactive analog VU342 MF Rouhier, RM Hine, ST Park, R Raphemot, J Denton, PM Piermarini, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2014 | 20 | 2014 |
| Plasmodium PK9 inhibitors promote growth of liver-stage parasites R Raphemot, AL Eubanks, M Toro-Moreno, RA Geiger, PF Hughes, KY Lu, ... Cell chemical biology 26 (3), 411-419. e7, 2019 | 16 | 2019 |
| Toxoplasma and Plasmodium associate with host Arfs during infection EA Schroeder, M Toro-Moreno, R Raphemot, K Sylvester, IC Colón, ... Msphere 9 (3), e00770-23, 2024 | | 2024 |
| EDHS‐206, an Exquisitely Selective Inhibitor of TAK1, Targets Pro Survival TNFα‐Dependent Signaling, Inducing Apoptosis in Rheumatoid Arthritis and Breast Cancer Models J Totzke, D Gurbani, R Raphemot, PF Hughes, K Bodoor, DA Carlson, ... Targets Pro Survival TNFα‐Dependent Signaling, Inducing Apoptosis in …, 2018 | | 2018 |
| A chemical biology approach reveals ubiquitin signaling in Plasmodium R Raphemot, A Eubanks, J Totzke, D Gurbani, D Carlson, K Westover, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
| Characterizing the atypical protein kinase 9 in Plasmodium A Eubanks, R Raphemot, E Derbyshire ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
