Structural basis for sequestration and autoinhibition of cGAS by chromatin S Michalski, CC de Oliveira Mann, CA Stafford, G Witte, J Bartho, ... Nature 587 (7835), 678-682, 2020 | 186 | 2020 |
TLR8 is a sensor of RNase T2 degradation products W Greulich, M Wagner, MM Gaidt, C Stafford, Y Cheng, A Linder, T Carell, ... Cell 179 (6), 1264-1275. e13, 2019 | 141 | 2019 |
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins SC Xie, C Dogovski, E Hanssen, F Chiu, T Yang, MP Crespo, C Stafford, ... Journal of Cell Science 129 (2), 406-416, 2016 | 128 | 2016 |
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Nature communications 6 (1), 6442, 2015 | 125 | 2015 |
Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology FM Hansen, MC Tanzer, F Brüning, I Bludau, C Stafford, BA Schulman, ... Nature Communications 12 (1), 254, 2021 | 91 | 2021 |
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy JP Bernardini, JM Brouwer, IKL Tan, JJ Sandow, S Huang, CA Stafford, ... The EMBO journal 38 (2), e99916, 2019 | 88 | 2019 |
Quantitative and dynamic catalogs of proteins released during apoptotic and necroptotic cell death MC Tanzer, A Frauenstein, CA Stafford, K Phulphagar, M Mann, ... Cell reports 30 (4), 1260-1270. e5, 2020 | 63 | 2020 |
Oligomerization‐driven MLKL ubiquitylation antagonizes necroptosis Z Liu, LF Dagley, K Shield‐Artin, SN Young, A Bankovacki, X Wang, ... The EMBO journal 40 (23), e103718, 2021 | 50 | 2021 |
IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network NA Schmacke, F O’Duill, MM Gaidt, I Szymanska, JM Kamper, ... Immunity 55 (12), 2271-2284. e7, 2022 | 49 | 2022 |
Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling MC Tanzer, I Bludau, CA Stafford, V Hornung, M Mann Nature communications 12 (1), 6053, 2021 | 39 | 2021 |
IAPs regulate distinct innate immune pathways to co-ordinate the response to bacterial peptidoglycans CA Stafford, KE Lawlor, VJ Heim, A Bankovacki, JP Bernardini, J Silke, ... Cell Reports 22 (6), 1496-1508, 2018 | 35 | 2018 |
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation CA Stafford, AM Gassauer, CC de Oliveira Mann, MC Tanzer, E Fessler, ... Nature 609 (7927), 590-596, 2022 | 27 | 2022 |
Priming enables a NEK7-independent route of NLRP3 activation NA Schmacke, MM Gaidt, I Szymanska, F O’Duill, CA Stafford, D Chauhan, ... bioRxiv, 799320, 2019 | 20 | 2019 |
A regulatory region on RIPK 2 is required for XIAP binding and NOD signaling activity VJ Heim, LF Dagley, CA Stafford, FM Hansen, E Clayer, A Bankovacki, ... EMBO reports 21 (11), e50400, 2020 | 9 | 2020 |
Nanoscale organization of the endogenous ASC speck IM Glück, GP Mathias, S Strauss, V Rat, I Gialdini, TS Ebert, C Stafford, ... Iscience 26 (12), 2023 | 4 | 2023 |
Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages LL Andersen, Y Huang, C Urban, L Oubraham, E Winheim, C Stafford, ... The EMBO Journal 42 (23), e113279, 2023 | 1 | 2023 |
A regulatory interface on RIPK2 is required for XIAP binding and NOD signaling activity VJ Heim, LF Dagley, CA Stafford, FM Hansen, E Clayer, A Bankovacki, ... bioRxiv, 2020.03. 12.988725, 2020 | 1 | 2020 |
A NODding acquaintance with ER stress CA Stafford, U Nachbur Cell Death Discovery 2 (1), 1-2, 2016 | 1 | 2016 |
A regulatory region onRIPK2 is required forXIAPbinding andNODsignaling activity VJ Heim, LF Dagley, CA Stafford, FM Hansen, E Clayer, A Bankovacki, ... EMBO REPORTS, 2020 | | 2020 |
Institute Research Publication Repository U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Communications 6, 6442, 2015 | | 2015 |