Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. TW Sedlak, ZN Oltvai, E Yang, K Wang, LH Boise, CB Thompson, ... Proceedings of the National Academy of Sciences 92 (17), 7834-7838, 1995 | 1119 | 1995 |
The diverse functions of GAPDH: views from different subcellular compartments C Tristan, N Shahani, TW Sedlak, A Sawa Cellular Signalling 23 (2), 317-323, 2011 | 719 | 2011 |
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles TW Sedlak, M Saleh, DS Higginson, BD Paul, KR Juluri, SH Snyder Proceedings of the National Academy of Sciences 106 (13), 5171-5176, 2009 | 589 | 2009 |
Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle TW Sedlak, SH Snyder Pediatrics 113 (6), 1776-1782, 2004 | 569 | 2004 |
Hematopoietic Malignancies Demonstrate Loss-of-Function Mutations ofBAX JPP Meijerink, EJBM Mensink, K Wang, TW Sedlak, AW Slöetjes, ... Blood, The Journal of the American Society of Hematology 91 (8), 2991-2997, 1998 | 390 | 1998 |
Oxidative stress and schizophrenia: recent breakthroughs from an old story FE Emiliani, TW Sedlak, A Sawa Current Opinion in Psychiatry 27 (3), 185-190, 2014 | 205 | 2014 |
Implications for reactive oxygen species in schizophrenia pathogenesis M Koga, AV Serritella, A Sawa, TW Sedlak Schizophrenia Research 176 (1), 52-71, 2016 | 167 | 2016 |
Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation D Giovinazzo, B Bursac, JI Sbodio, S Nalluru, T Vignane, AM Snowman, ... Proceedings of the National Academy of Sciences 118 (4), e2017225118, 2021 | 155 | 2021 |
Assessing brain metabolism with 7-T proton magnetic resonance spectroscopy in patients with first-episode psychosis AM Wang, S Pradhan, JM Coughlin, A Trivedi, SL DuBois, JL Crawford, ... JAMA Psychiatry 76 (3), 314-323, 2019 | 150 | 2019 |
The glutathione cycle shapes synaptic glutamate activity TW Sedlak, BD Paul, GM Parker, LD Hester, AM Snowman, Y Taniguchi, ... Proceedings of the National Academy of Sciences 116 (7), 2701-2706, 2019 | 133 | 2019 |
Constituents of bile, bilirubin and TUDCA, protect against oxidative stress‐induced retinal degeneration BC Oveson, T Iwase, SF Hackett, SY Lee, S Usui, TW Sedlak, SH Snyder, ... Journal of Neurochemistry 116 (1), 144-153, 2011 | 111 | 2011 |
Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness AW Johnson, H Jaaro-Peled, N Shahani, TW Sedlak, S Zoubovsky, ... Proceedings of the National Academy of Sciences 110 (30), 12462-12467, 2013 | 109 | 2013 |
Heme oxygenase-2 is activated by calcium-calmodulin D Boehning, L Sedaghat, TW Sedlak, SH Snyder Journal of Biological Chemistry 279 (30), 30927-30930, 2004 | 101 | 2004 |
Reduction of plasma glutathione in psychosis associated with schizophrenia and bipolar disorder in translational psychiatry LG Nucifora, T Tanaka, LN Hayes, M Kim, BJ Lee, T Matsuda, ... Translational Psychiatry 7 (8), e1215-e1215, 2017 | 93 | 2017 |
Glutathione is a physiologic reservoir of neuronal glutamate M Koga, AV Serritella, MM Messmer, A Hayashi-Takagi, LD Hester, ... Biochemical and Biophysical Research Communications 409 (4), 596-602, 2011 | 88 | 2011 |
Bilirubin links heme metabolism to neuroprotection by scavenging superoxide C Vasavda, R Kothari, AP Malla, R Tokhunts, A Lin, M Ji, C Ricco, R Xu, ... Cell Chemical Biology 26 (10), 1450-1460. e7, 2019 | 85 | 2019 |
Sulforaphane augments glutathione and influences brain metabolites in human subjects: a clinical pilot study TW Sedlak, LG Nucifora, M Koga, LS Shaffer, C Higgs, T Tanaka, ... Molecular Neuropsychiatry 3 (4), 214-222, 2018 | 72 | 2018 |
Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity H Perlman, M Sata, A Le Roux, TW Sedlak, D Branellec, K Walsh EMBO Journal 17 (13), 3576-3586, 1998 | 63 | 1998 |
DISC1 regulates trafficking and processing of APP and Aβ generation N Shahani, S Seshadri, H Jaaro-Peled, K Ishizuka, Y Hirota-Tsuyada, ... Molecular Psychiatry 20 (7), 874-879, 2015 | 61 | 2015 |
Messenger molecules and cell death: therapeutic implications TW Sedlak, SH Snyder JAMA 295 (1), 81-89, 2006 | 58 | 2006 |