关注
Jonas Demeulemeester
Jonas Demeulemeester
Group Leader @ VIB – KU Leuven Center for Cancer Biology
在 kuleuven.be 的电子邮件经过验证
标题
引用次数
引用次数
年份
Pan-cancer analysis of whole genomes
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Nature 578 (7793), 82, 2020
1771*2020
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, SG Rosado, D Rosebrock, ...
Nature, 122–128, 2020
9032020
Neoantigen-directed immune escape in lung cancer evolution
R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ...
Nature 567 (7749), 479-485, 2019
7512019
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...
Cell 184 (8), 2239-2254. e39, 2021
357*2021
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ...
Nature genetics 52 (3), 306-319, 2020
3492020
Pervasive chromosomal instability and karyotype order in tumour evolution
TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ...
Nature 587 (7832), 126-132, 2020
2912020
Small-molecule inhibitors of the LEDGF/p75 binding site of integrase block HIV replication and modulate integrase multimerization
F Christ, S Shaw, J Demeulemeester, BA Desimmie, A Marchand, S Butler, ...
Antimicrobial agents and chemotherapy 56 (8), 4365-4374, 2012
2132012
The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites
J De Rijck, C de Kogel, J Demeulemeester, S Vets, S El Ashkar, N Malani, ...
Cell reports 5 (4), 886-894, 2013
1922013
LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
BA Desimmie, R Schrijvers, J Demeulemeester, D Borrenberghs, ...
Retrovirology 10, 1-16, 2013
1692013
LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs
R Schrijvers, J De Rijck, J Demeulemeester, N Adachi, S Vets, K Ronen, ...
PLoS pathogens 8 (3), e1002558, 2012
1482012
Recurrent rearrangements of FOS and FOSB define osteoblastoma
MW Fittall, W Mifsud, N Pillay, H Ye, AC Strobl, A Verfaillie, ...
Nature communications 9 (1), 2150, 2018
1222018
LEDGIN-mediated inhibition of integrase–LEDGF/p75 interaction reduces reactivation of residual latent HIV
LS Vranckx, J Demeulemeester, S Saleh, A Boll, G Vansant, R Schrijvers, ...
EBioMedicine 8, 248-264, 2016
1132016
Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
O Marin-Bejar, A Rogiers, M Dewaele, J Femel, P Karras, J Pozniak, ...
Cancer Cell 39 (8), 1135-1149. e8, 2021
982021
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
J Cheng, J Demeulemeester, DC Wedge, HKM Vollan, JJ Pitt, ...
Nature Communications 8 (1), 1221, 2017
932017
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
J Demeulemeester, P Kumar, EK Møller, S Nord, DC Wedge, A Peterson, ...
Genome biology 17, 1-15, 2016
882016
Retroviral integration: site matters: mechanisms and consequences of retroviral integration site selection
J Demeulemeester, J De Rijck, R Gijsbers, Z Debyser
Bioessays 37 (11), 1202-1214, 2015
872015
LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006–2014)
J Demeulemeester, P Chaltin, A Marchand, M De Maeyer, Z Debyser, ...
Expert opinion on therapeutic patents 24 (6), 609-632, 2014
852014
4-Substituted 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as a Novel Class of HIV-1 Integrase Inhibitors
M Billamboz, V Suchaud, F Bailly, C Lion, J Demeulemeester, C Calmels, ...
ACS Medicinal Chemistry Letters 4 (7), 606-611, 2013
682013
Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif
P Tesina, K Čermáková, M Hořejší, K Procházková, M Fábry, S Sharma, ...
Nature communications 6 (1), 7968, 2015
612015
Genomic–transcriptomic evolution in lung cancer and metastasis
C Martínez-Ruiz, JRM Black, C Puttick, MS Hill, J Demeulemeester, ...
Nature 616 (7957), 543-552, 2023
582023
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