Acylhydrazone derivatives: a patent review RC Maia, R Tesch, CAM Fraga Expert opinion on therapeutic patents 24 (11), 1161-1170, 2014 | 65 | 2014 |
Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline‐induced pulmonary hypertension in rats AKN Alencar, SL Pereira, TL Montagnoli, RC Maia, AE Kümmerle, ... British journal of pharmacology 169 (5), 953-962, 2013 | 52 | 2013 |
The use of conformational restriction in medicinal chemistry P de Sena M Pinheiro, DA Rodrigues, R do Couto Maia, S Thota, ... Current topics in medicinal chemistry 19 (19), 1712-1733, 2019 | 32 | 2019 |
Synthesis and analgesic profile of conformationally constrained N-acylhydrazone analogues: Discovery of novel N-arylideneamino quinazolin-4 (3H)-one compounds derived from … RC Maia, LL Silva, EF Mazzeu, MM Fumian, CM de Rezende, ... Bioorganic & medicinal chemistry 17 (18), 6517-6525, 2009 | 32 | 2009 |
Phenylpiperazine derivatives: a patent review (2006–present) RC Maia, R Tesch, CAM Fraga Expert opinion on therapeutic patents 22 (10), 1169-1178, 2012 | 30 | 2012 |
Sodium–glucose cotransporter 2 (SGLT-2) inhibitors: a new antidiabetic drug class PN da Silva, RA da Conceição, R do Couto Maia, ML de Castro Barbosa MedChemComm 9 (8), 1273-1281, 2018 | 20 | 2018 |
Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (M PRO) through in silico screening supported by molecular docking and a fragment-based pharmacophore … LS Franco, RC Maia, EJ Barreiro RSC medicinal chemistry 12 (1), 110-119, 2021 | 18 | 2021 |
Discovery of Dual Chemotherapy Drug Candidates Designed by Molecular Hybridization R do Couto Maia, C Alberto Manssour Fraga Current Enzyme Inhibition 6 (4), 171-182, 2010 | 18 | 2010 |
LASSBio‐881: an N‐acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by … JLM Tributino, MLH Santos, CM Mesquita, CKF Lima, LL Silva, RC Maia, ... British journal of pharmacology 159 (8), 1716-1723, 2010 | 17 | 2010 |
N-acylhydrazone improves exercise intolerance in rats submitted to myocardial infarction by the recovery of calcium homeostasis in skeletal muscle JS da Silva, SL Pereira, R do Couto Maia, SS Landgraf, C Caruso-Neves, ... Life sciences 94 (1), 30-36, 2014 | 13 | 2014 |
LASSBio-1425, an analog of thalidomide, decreases triglyceride and increases HDL cholesterol levels by inhibition of TNF-α production MM Fumian, NAV da Motta, R Maia, CAM Fraga, EJ Barreiro, FCF de Brito International Journal of Cardiology 202, 497-499, 2016 | 11 | 2016 |
Recent trends in neuropathic pain patents RC Maia Expert Opinion on Therapeutic Patents 27 (5), 539-546, 2017 | 8 | 2017 |
Novel furfurylidene N-acylhydrazones derived from natural safrole: discovery of LASSBio-1215, a new potent antiplatelet prototype APC Rodrigues, LMM Costa, BLR Santos, RC Maia, ALP Miranda, ... Journal of Enzyme Inhibition and Medicinal Chemistry 27 (1), 101-109, 2012 | 7 | 2012 |
Synthesis and Biological Evaluation of Pyrazolo [3, 4-b] pyridin-4-ones as a New Class of Topoisomerase II Inhibitors M Aghazadeh Tabrizi, P Giovanni Baraldi, S Baraldi, F Prencipe, D Preti, ... Medicinal Chemistry 11 (4), 342-353, 2015 | 6 | 2015 |
Novel phosphatidylinositol 4-kinases III beta (PI4KIIIβ) inhibitors discovered by virtual screening using free energy models NM Colodette, LS Franco, RC Maia, HH Fokoue, CMR Sant’Anna, ... Journal of Computer-Aided Molecular Design 34, 1091-1103, 2020 | 5 | 2020 |
2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties DR de Oliveira, RC Maia, PR de Carvalho França, PD Fernandes, ... Pharmaceuticals 15 (12), 1519, 2022 | 2 | 2022 |
Synthesis and in silico and in vitro evaluation of trimethoxy-benzamides designed as anti-prion derivatives RA Conceição, LM Ascari, NC Ferreira, CF Goes, CO Matos, AS Pinheiro, ... Medicinal Chemistry Research 28, 2128-2141, 2019 | 1 | 2019 |
Compostos fenil-pirazóis ftalimídicos bioativos, processo para preparação dos compostos, seu uso e composições farmacêuticas EJL Barreiros, CAM Fraga, ALP Miranda, CKF Lima, MM Fumian, ... Brasil, 2016 | | 2016 |
Discovery of dual chemotherapy drug candidates designed by molecular hybridization R Maia, CAM Fraga Curr Enzyme Inhib 6, 171-182, 2010 | | 2010 |