A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3 IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ... Nature genetics 40 (5), 623-630, 2008 | 657 | 2008 |
Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process KE Caudle, TE Klein, JM Hoffman, DJ Müller, M Whirl-Carrillo, L Gong, ... Current drug metabolism 15 (2), 209, 2014 | 440 | 2014 |
Cytochrome P450 gene polymorphism and cancer JAG Agúndez Current drug metabolism 5 (3), 211-224, 2004 | 379 | 2004 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C19 and Voriconazole Therapy B Moriyama, AO Obeng, J Barbarino, SR Penzak, SA Henning, SA Scott, ... Clinical Pharmacology & Therapeutics 102 (1), 45-51, 2017 | 351 | 2017 |
Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti‐Inflammatory Drugs KN Theken, CR Lee, L Gong, KE Caudle, CM Formea, A Gaedigk, ... Clinical Pharmacology & Therapeutics 108 (2), 191-200, 2020 | 266 | 2020 |
Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population JAG Agúndez, MC Ledesma, JM Ladero, J Benítez Clinical Pharmacology & Therapeutics 57 (3), 265-269, 1995 | 256 | 1995 |
Glutathione S‐transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug‐induced liver injury MI Lucena, RJ Andrade, C Martínez, E Ulzurrun, E García‐Martín, ... Hepatology 48 (2), 588-596, 2008 | 242 | 2008 |
Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism M Oscarson, RA McLellan, H Gullstén, JAG Agúndez, J Benı́tez, A Rautio, ... FEBS letters 460 (2), 321-327, 1999 | 242 | 1999 |
Characteristics of subjects experiencing hypersensitivity to non‐steroidal anti‐inflammatory drugs: patterns of response I Doña, N Blanca‐López, JA Cornejo‐Garcia, MJ Torres, JJ Laguna, ... Clinical & Experimental Allergy 41 (1), 86-95, 2011 | 239 | 2011 |
Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms E García‐Martín, C Martínez, B Tabarés, J Frías, JAG Agúndez Clinical Pharmacology & Therapeutics 76 (2), 119-127, 2004 | 229 | 2004 |
PharmVar GeneFocus: CYP2D6 C Nofziger, AJ Turner, K Sangkuhl, M Whirl‐Carrillo, JAG Agúndez, ... Clinical Pharmacology & Therapeutics 107 (1), 154-170, 2020 | 204 | 2020 |
Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review Z Vinarov, M Abdallah, JAG Agundez, K Allegaert, AW Basit, ... European Journal of Pharmaceutical Sciences 162, 105812, 2021 | 201 | 2021 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron GC Bell, KE Caudle, M Whirl-Carrillo, RJ Gordon, K Hikino, CA Prows, ... Clinical pharmacology and therapeutics 102 (2), 213, 2017 | 198 | 2017 |
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting LV Kalman, JAG Agúndez, ML Appell, JL Black, GC Bell, S Boukouvala, ... Clinical Pharmacology & Therapeutics 99 (2), 172-185, 2016 | 191 | 2016 |
Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use C Martínez, G Blanco, JM Ladero, E García‐Martín, C Taxonera, ... British journal of pharmacology 141 (2), 205-208, 2004 | 190 | 2004 |
Interethnic and Intraethnic Variability of CYP2C8 and CYP2C9 Polymorphisms in Healthy Individuals E García-Martín, C Martínez, JM Ladero, JAG Agúndez Molecular diagnosis & therapy 10, 29-40, 2006 | 187 | 2006 |
Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2‐receptor antagonists C Martínez, C Albet, JAG Agúndez, E Herrero, JA Carrillo, M Márquez, ... Clinical pharmacology & therapeutics 65 (4), 369-376, 1999 | 186 | 1999 |
Changing the Si distribution in SAPO-11 by synthesis with surfactants improves the hydroisomerization/dewaxing properties T Blasco, A Chica, A Corma, WJ Murphy, J Agúndez-Rodríguez, ... Journal of Catalysis 242 (1), 153-161, 2006 | 182 | 2006 |
CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity E García‐Martín, C Martínez, RM Pizarro, FJ García‐Gamito, H Gullsten, ... Clinical pharmacology & therapeutics 71 (3), 196-204, 2002 | 172 | 2002 |
The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)‐ibuprofen enantiomer in healthy subjects C Martínez, E García‐Martín, G Blanco, FJG Gamito, JM Ladero, ... British journal of clinical pharmacology 59 (1), 62-68, 2005 | 169 | 2005 |