Deep Learning-driven research for drug discovery: Tackling Malaria BJ Neves, RC Braga, VM Alves, MNN Lima, GC Cassiano, EN Muratov, ... PLoS computational biology 16 (2), e1007025, 2020 | 56 | 2020 |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax LM Storti-Melo, DR Da Costa, WC Souza-Neiras, GC Cassiano, ... Acta tropica 121 (2), 152-155, 2012 | 32 | 2012 |
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies AC Pippione, S Sainas, P Goyal, I Fritzson, GC Cassiano, A Giraudo, ... European journal of medicinal chemistry 163, 266-280, 2019 | 31 | 2019 |
Plasmodium vivax circumsporozoite variants and Duffy blood group genotypes in the Brazilian Amazon region LM Storti-Melo, WC de Souza-Neiras, GC Cassiano, ACP Joazeiro, ... Transactions of the Royal Society of Tropical Medicine and Hygiene 103 (7 …, 2009 | 31 | 2009 |
Human interleukin 2 (IL-2) promotion of immune regulation and clinical outcomes: a review MP Capobianco, GC Cassiano, AA da Cruz Furini, LM Storti de Melo, ... J Cytokine Biol 1 (109), 14-7, 2016 | 27 | 2016 |
Impact of population admixture on the distribution of immune response co-stimulatory genes polymorphisms in a Brazilian population GC Cassiano, EJM Santos, MHT Maia, A da Cruz Furini, LM Storti-Melo, ... Human Immunology 76 (11), 836-842, 2015 | 25 | 2015 |
Plasmodium vivax circumsporozoite genotypes: a limited variation or new subspecies with major biological consequences? WC Souza-Neiras, LM Storti-Melo, GC Cassiano, VSCA Couto, ... Malaria journal 9, 1-8, 2010 | 25 | 2010 |
QSAR-driven design and discovery of novel compounds with antiplasmodial and transmission blocking activities MNN Lima, CC Melo-Filho, GC Cassiano, BJ Neves, VM Alves, RC Braga, ... Frontiers in Pharmacology 9, 146, 2018 | 24 | 2018 |
Integrative multi-kinase approach for the identification of potent antiplasmodial hits MNN Lima, GC Cassiano, KCP Tomaz, AC Silva, BKP Sousa, LT Ferreira, ... Frontiers in chemistry 7, 773, 2019 | 23 | 2019 |
Polymorphisms in Plasmodium vivax Circumsporozoite Protein (CSP) Influence Parasite Burden and Cytokine Balance in a Pre-Amazon Endemic Area from Brazil BP Ribeiro, GC Cassiano, RM de Souza, DN Cysne, MAG Grisotto, ... PLoS neglected tropical diseases 10 (3), e0004479, 2016 | 22 | 2016 |
Evaluation of the naturally acquired antibody immune response to the Pv200L N-terminal fragment of Plasmodium vivax merozoite surface protein-1 in four areas of the Amazon … LM Storti-Melo, WC Souza-Neiras, GC Cassiano, LC Taveira, AJ Cordeiro, ... The American journal of tropical medicine and hygiene 84 (Suppl 2), 58, 2011 | 21 | 2011 |
Development of PCR–RFLP assay for the discrimination of Plasmodium species and variants of P. vivax (VK210, VK247 and P. vivax-like) in Anopheles mosquitoes GC Cassiano, LM Storti-Melo, MM Póvoa, AKR Galardo, ARB Rossit, ... Acta tropica 118 (2), 118-122, 2011 | 18 | 2011 |
Small for gestational age very preterm infants present a higher risk of developing bronchopulmonary dysplasia G Rocha, FF De Lima, AP Machado, H Guimarães, E Proença, ... Journal of neonatal-perinatal medicine 12 (4), 419-427, 2019 | 17 | 2019 |
Polymorphisms in B Cell Co-Stimulatory Genes Are Associated with IgG Antibody Responses against Blood–Stage Proteins of Plasmodium vivax GC Cassiano, AAC Furini, MP Capobianco, LM Storti-Melo, MG Cunha, ... PLoS One 11 (2), e0149581, 2016 | 16 | 2016 |
Plasmodium vivax Cell Traversal Protein for Ookinetes and Sporozoites (PvCelTOS) gene sequence and potential epitopes are highly conserved among isolates … L Bitencourt Chaves, DS Perce-da-Silva, RN Rodrigues-da-Silva, ... PLoS neglected tropical diseases 11 (2), e0005344, 2017 | 15 | 2017 |
Frequency of ABO blood group system polymorphisms in Plasmodium falciparum malaria patients and blood donors from the Brazilian Amazon region. DB Carvalho, LC de Mattos, WC Souza-Neiras, CR Bonini-Domingos, ... Genetics and molecular research: GMR, 1443-1449, 2010 | 14 | 2010 |
Computational chemogenomics drug repositioning strategy enables the discovery of epirubicin as a new repurposed hit for Plasmodium falciparum and P. vivax LT Ferreira, J Rodrigues, GC Cassiano, TA Tavella, KCP Tomaz, ... Antimicrobial agents and chemotherapy 64 (9), 10.1128/aac. 02041-19, 2020 | 13 | 2020 |
Immunogenetic markers associated with a naturally acquired humoral immune response against an N-terminal antigen of Plasmodium vivax merozoite surface … GC Cassiano, AAC Furini, MP Capobianco, LM Storti-Melo, ME Almeida, ... Malaria Journal 15, 1-11, 2016 | 13 | 2016 |
Frequency of TNFA, INFG, and IL10 Gene Polymorphisms and Their Association with Malaria Vivax and Genomic Ancestry AAC Furini, GC Cassiano, M Petrolini Capobianco, SEB Dos Santos, ... Mediators of Inflammation 2016 (1), 5168363, 2016 | 13 | 2016 |
Humoral immune responses against the malaria vaccine candidate antigen Plasmodium vivax AMA-1 and IL-4 gene polymorphisms in individuals living in an endemic area of the … FMMB Tomaz, AA da Cruz Furini, MP Capobianco, MM Povoa, ... Cytokine 74 (2), 273-278, 2015 | 13 | 2015 |